Wikipedia

Howard W. Jones

Howard Wilbur Jones, Jr. (December 30, 1910 – July 31, 2015) was an American gynecological surgeon and in vitro fertilization (IVF) specialist. Jones and his wife, Georgeanna Seegar Jones, were two of the earliest reproductive medicine specialists in the United States. They established the reproductive medicine center that was responsible for the birth of the first IVF baby in the U.S. He wrote articles on the beginning of human personhood and testified before legislators on the same subject. He was one of the early physicians to perform sex reassignment surgeries.

Howard W. Jones
Jones in a 2010 interview
Born
Howard Wilbur Jones, Jr.

(1910-12-30)December 30, 1910
Baltimore, Maryland, U.S.
DiedJuly 31, 2015(2015-07-31) (aged 104)
Norfolk, Virginia, U.S.
EducationJohns Hopkins School of Medicine
Medical career
ProfessionMedicine
InstitutionsJohns Hopkins School of Medicine
Eastern Virginia Medical School
Sub-specialtiesIn vitro fertilization

Jones was on the faculty at Johns Hopkins School of Medicine from the 1940s until his mandatory retirement from the institution in 1978. He and his wife moved to Virginia and were affiliated with Eastern Virginia Medical School (EVMS). Jones retired in the 1990s, but he continued to write and spent time at EVMS until shortly before his death.

Early life

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Jones was born in Baltimore to Howard Wilbur Jones, Sr. and Edith Ruth Marling Jones on December 30, 1910. Even though he lived in the city, Jones was educated for a few years in a rural public school to avoid the city public school system. When Jones was a child, he went on house calls and hospital visits with his father, who was a physician. Jones's father died when he was 13 years old. Jones's mother moved him to a private school after the death of his father.[1]

He earned an undergraduate degree from Amherst College in 1931 and a medical degree from Johns Hopkins School of Medicine in 1935.[2] Jones completed a residency in surgery and then joined the U.S. Army during World War II, leading an Auxiliary Surgical Group team in Patton's Third Army. After the war, Jones was invited to complete a second residency in gynecology.[1]

Career

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Jones and his wife joined the faculty at Johns Hopkins on a part-time basis in 1948.[2] He was the initial treating physician of Henrietta Lacks when she presented to Johns Hopkins with cancer in 1951.[3] Jones took a biopsy of Lacks's tumor and sent samples to his laboratory colleagues. The cells, later known as HeLa cells, grew at an astonishing rate in the lab and were shipped and sold to researchers for various purposes. Research with the cells helped to facilitate medical breakthroughs, including the vaccines for polio and human papillomavirus, though controversy later arose because the cells were being used without the knowledge of Lacks or her family.[4] Jones's role in the Lacks case was described in the book The Immortal Life of Henrietta Lacks.[3]

In 1960, the Joneses left private practice to join the Johns Hopkins faculty full-time.[2] While there, Howard Jones participated in sex reassignment surgeries. In 1967, when sexual identity specialist John Money recommended sex reassignment for a child named David Reimer, Jones performed the surgery. Reimer, who had suffered a severe penile injury during a circumcision, was 22 months old when Jones removed his testicles, shaped his scrotal tissue to look like labia and repositioned his urethral opening. Money declared the procedure a success.[5] The case became controversial when Milton Diamond published a 1997 follow-up study[6] revealing Reimer experienced gender identity problems and lived as a man in adulthood. Reimer ultimately committed suicide at the age of 38.[7]

In the 1960s, he was able to participate in experiments involving sperm and oocytes with Robert Edwards, the doctor whose work later created the world's first test tube baby.[8] In 1978, Jones faced mandatory retirement from Johns Hopkins.[9] The Joneses moved to Virginia and established the Jones Institute for Reproductive Medicine at the Eastern Virginia Medical School (EVMS). They created an in vitro fertilization (IVF) program at EVMS, which resulted in the 1981 birth of Elizabeth Jordan Carr, the first test tube baby in the country.[10] Before his first successful IVF treatment, the clinic experienced 41 failed attempts at IVF.[9]

After his wife developed Alzheimer's disease in the late 1990s, Jones officially retired from his institute so that he could care for her. However, as of 2013, Jones still spent a few hours per day at EVMS and was writing his twelfth book.[10] In February 2012, Jones successfully appealed to Virginia legislators to stop a bill that would have declared life to begin at conception. Jones said that the bill would have interfered with medical treatment for infertility.[3]

Jones has been recognized with a Distinguished Service Award from the American Congress of Obstetricians and Gynecologists.[11] He was named a Fellow ad eundem of the Royal College of Obstetricians and Gynaecologists in 1986.[12] Jones and his wife received Distinguished Alumnus Awards from Johns Hopkins University in 1997.[13]

Personal life

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In 2011, Jones wrote an article for The Yale Journal for Humanities in Medicine on his keys to a long life. "First, I am the result of a tremendous shuffling of genetic material, which included some 3 billion potential variables. I got lucky. My combination seems to confer longevity," he said. He also wrote that his career and his family life had been enjoyable and rewarding, which had enhanced his longevity.[14]

Jones was married for 64 years before his wife's 2005 death.[15] A son, Howard Jones, III, became the chairman of obstetrics and gynecology at Vanderbilt University Medical Center in 2009.[16] A daughter, Georgeanna Jones Klingensmith, is a pediatric endocrinologist in Denver.[17]

Death

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Jones died of respiratory failure on July 31, 2015, at the age of 104. He had been hospitalized at the Sentara Heart Hospital for the two weeks preceding his death.[18]

Selected publications

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Articles

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  • Jones Howard (2005). "Twenty-Five Years of In Vitro Fertilization: A Look Back and a Look Forward". Obstetrical & Gynecological Survey. 60 (2): 75–6. doi:10.1097/01.ogx.0000153993.45283.e8.
  • Jones Howard W.; Toner James P. (1993). "The Infertile Couple". The New England Journal of Medicine. 329 (23): 1710–1715. doi:10.1056/nejm199312023292307. PMID 8166801.

Books

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References

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  1. ^ a b "Howard Wilber Jones Jr". The Embryo Project Encyclopedia. Arizona Board of Regents. Retrieved July 9, 2014.
  2. ^ a b c "The Howard W. Jones, Jr. Collection". Johns Hopkins Medical Institutions. Archived from the original on September 23, 2012. Retrieved July 8, 2014.
  3. ^ a b c Simpson, Elizabeth. "Dr. Howard W. Jones Jr., scientist behind United States first in-vitro fertilization baby, telling his story". WUSA (TV). Archived from the original on July 14, 2014. Retrieved July 9, 2014.
  4. ^ Mobley, Regina. "Father of in vitro fertilization weighs in on future of reproductive medicine". WVEC. Archived from the original on July 14, 2014. Retrieved July 9, 2014.
  5. ^ Colapinto, John (December 11, 1997). "The case of John/Joan" (PDF). Rolling Stone. Archived from the original (PDF) on July 14, 2014. Retrieved July 9, 2014.
  6. ^ Diamond, Milton; Sigmundson, H. Keith (March 1997). "Sex reassignment at birth. Long-term review and clinical implications". Arch Pediatr Adolesc Med. 151 (3): 298–304. doi:10.1001/archpedi.1997.02170400084015. PMID 9080940. Retrieved 15 May 2013.
  7. ^ "David Reimer, 38, subject of the John/Joan case". The New York Times. The New York Times. May 12, 2004. Retrieved July 9, 2014.
  8. ^ Ombelet, Willem (2011). "A tribute to Robert Edwards and Howard Jones Jr". Facts, Views & Vision in ObGyn. 3 (1): 33–43. PMC 3991406. PMID 24753845.
  9. ^ a b Epstein, Randi (March 22, 2010). "Pioneer reflects on future of reproductive medicine". The New York Times. The New York Times. Retrieved July 8, 2014.
  10. ^ a b Simpson, Elizabeth. "At 102, he's still focused on the future of fertility". PilotOnline.com. Retrieved July 8, 2014.
  11. ^ "ACM Service Awards and Honorary Fellowships". American Congress of Obstetricians and Gynecologists. Retrieved August 1, 2015.
  12. ^ "Fellows ad eundem". Royal College of Obstetricians and Gynaecologists. Retrieved August 1, 2015.
  13. ^ "The Distinguished Alumnus Award". Johns Hopkins University. Retrieved August 1, 2015.
  14. ^ Jones, Howard W. "A centenarian's secrets for longevity". The Yale Journal for Humanities in Medicine. Yale University. Archived from the original on July 14, 2014. Retrieved July 9, 2014.
  15. ^ O'Connor, Anahad (March 28, 2005). "Georgeanna S. Jones, in vitro conception pioneer, dies at 92". The New York Times. The New York Times. Retrieved July 9, 2014.
  16. ^ "Jones named chair of Obstetrics and Gynecology". Vanderbilt University Medical Center. Retrieved July 9, 2014.[permanent dead link‍]
  17. ^ Epstein, Randi Hutter. "A miracle worker". Amherst Magazine. No. Fall 2011. Retrieved August 1, 2015.
  18. ^ "Hampton Roads, Dr Howard Jones whose work led to country's first IVF baby dies in Norfolk 104". Archived from the original on 2015-08-02. Retrieved 2015-07-31.
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