Garry Izrailevich Abelev (Russian: Гарри Израйлевич Абелев; 10 January 1928 – 23 December 2013) was a Russian scientist, Academician of the Russian Academy of Sciences (since 2000),[1] Doctor of Biological Sciences,[1] Honored Scientist of the Russian Federation (1998).[1] Laureate of the 1978 USSR State Prize.

Garry Izrailevich Abelev
Born(1928-01-10)10 January 1928
Died23 December 2013(2013-12-23) (aged 85)
Alma materMoscow State University (1950)
Known forimmunology, oncology
Awards1975 William B. Coley Award
1978 USSR State Prize
Honored Scientist of the Russian Federation (1998)
Scientific career
Fieldsbiochemistry
InstitutionsN.N. Blokhin Russian Cancer Research Center
N.F. Gamaleya Federal Research Center for Epidemiology & Microbiology
Moscow State University

Biography

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Abelev was born in Moscow in 1928.

He studied at the Lomonosov Moscow State University (now MSU) at the Faculty of Biology and Soil Science from 1945 and graduated from the Department of Biochemistry of Plants in 1950.[2]

In 1955 he defended his candidate's dissertation.[3] In 1963 he defended his doctoral dissertation.[4]

He worked at the N.F. Gamaleya Federal Research Center for Epidemiology & Microbiology from 1950 to 1977.[1] He was hired as a preparator in the Biochemistry Department, then moved to the Department of Virology and Immunology of Tumours under the lead of Lev Zilber. Abelev worked his way up to the head of the laboratory, and after Zilber's death he became head of the department.[5]

From 1964 to 2006 he worked as a lecturer at the Department of Virology at Faculty of Biology at the Moscow State University.[1] He has trained 22 Candidates and 4 Doctors of Sciences.[6]

In 1967 he received the title of Professor. He was a member of the Russian Academy of Natural Sciences (since 1990) and the New York Academy of Sciences. He also was an honorary member of the European Association of Cancer Research and a member of the Russian Supervisory Board of the International Science Counsil.[7]

In 1977, after a conflict with the directorate of the N.F. Gamaleya Federal Research Center for Epidemiology & Microbiology, his department was transferred to the N.N. Blokhin Russian Cancer Research Center.[8]

Died in 2013 in Moscow.[9]

Research

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In 1963, in an attempt to find specific tumour antigens, Abelev's department discovered an embryonic protein synthesised by liver cancer cells, α-fetoprotein. On this basis, the Abelev-Tatarinov reaction was developed for immunodiagnosis of liver cancer and teratoblastoma of the ovary. In addition, the detection of α-fetoprotein in hepatoma opened a new perspective on cancer as a reverse reprogramming of an adult cell into an embryonic cell.[10]

References

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  1. ^ a b c d e Russian Academy of Sciences (in Russian)
  2. ^ "Абелев Гарри Израйлевич". Российская академия наук (in Russian). 26 May 2022. Retrieved 23 January 2024.
  3. ^ "К 70-летию Онкоцентра. Публикация о российских корифеях онкоиммунологии, работавших в Онкоцентре, из журнала «Иммунология гемопоэза»" [To the 70th anniversary of the Oncology Center. Publication about Russian luminaries of oncoimmunology who worked at the Oncology Center, from the journal “Immunology of Hematopoiesis.”]. ronc.ru (in Russian). 7 September 2021. Retrieved 23 January 2024.
  4. ^ "Портрет: Г.И.Абелев | Летопись Московского университета". letopis.msu.ru. Archived from the original on 26 June 2022. Retrieved 23 January 2024.
  5. ^ "Умер академик РАН Г.И. Абелев". garriabelev.narod.ru. Retrieved 23 January 2024.
  6. ^ "Абелев Гарри Израйлевич". Российская академия наук (in Russian). 26 May 2022. Retrieved 23 January 2024.
  7. ^ "Абелев Гарри Израйлевич. | ИС АРАН". isaran.ru. Retrieved 23 January 2024.
  8. ^ "23 декабря 2013 года после тяжелой, продолжительной болезни на 86 году жизни ушел из жизни Гарри Израилевич Абелев" [On December 23, 2013, after a serious, long illness, Harry Izrailevich Abelev passed away at the age of 86.]. ronc.ru (in Russian). 24 June 2015. Retrieved 23 January 2024.
  9. ^ "Умер основоположник молекулярной диагностики рака академик Гарри Абелев". www.kommersant.ru (in Russian). 24 December 2013. Retrieved 23 January 2024.
  10. ^ "Андрей Гудков. Живая часть судьбы: Памяти Г. И. Абелева". garriabelev.narod.ru. Retrieved 23 January 2024.