Carotenoid 1,2-hydratase (EC 4.2.1.131, CrtC) is an enzyme with systematic name lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction
| Carotenoid 1,2-hydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.131 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (1) 1-hydroxy-1,2-dihydrolycopene lycopene + H2O
- (2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene 1-hydroxy-1,2-dihydrolycopene + H2O
In Rubrivivax gelatinosus and Thiocapsa roseopersicina both products are formed.
References
edit- ^ Steiger S, Mazet A, Sandmann G (June 2003). "Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus". Archives of Biochemistry and Biophysics. 414 (1): 51–8. doi:10.1016/s0003-9861(03)00099-7. PMID 12745254.
- ^ Hiseni A, Arends IW, Otten LG (August 2011). "Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina". Applied Microbiology and Biotechnology. 91 (4): 1029–36. doi:10.1007/s00253-011-3324-1. PMC 3145076. PMID 21590288.
External links
edit- Carotenoid+1,2-hydratase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
