Are You Sure? may refer to:
- Are You Sure? (film), a 1947 French film
- Are You Sure? (The Allisons song), 1961
- Are You Sure? (Kris Kross Amsterdam song), 2016
- "Are You Sure", song written by Ike Cargill (1943), sung by The Staple Singers on Freedom Highway
- "Are You Sure", song by So (1988)