Papers by Driliyas Sheikh
Indian Journal of Forensic and Community Medicine, 2024
Background: Suicide by hanging is a significant public health concern globally, with delayed deat... more Background: Suicide by hanging is a significant public health concern globally, with delayed deaths presenting unique challenges in understanding the underlying pathophysiology.In this observational study, cases of suicidal hanging resulting in delayed death were isolated, and comprehensive analyses were performed. Data collection included detailed histories of the suicidal attempts, circumstances surrounding the events, medical treatment records, and thorough autopsy examinations, including histopathological analyses.
Aim and Objective: This study aims to investigate cases of delayed death by hanging and analyse the associated pathophysiological mechanisms.
Results: Three cases of delayed death by hanging were identified and analysed in this study. Each case involved individuals who initially survived the suicidal attempts and received medical treatment. Despite efforts, all three individuals succumbed to their injuries after a period of time. Autopsy findings revealed characteristic signs of hanging, along with evidence of post-obstructive pulmonary edema as the cause of death in each case.
Conclusions: This study highlights the occurrence of delayed deaths following suicidal hanging and underscores the importance of understanding the pathophysiological mechanisms involved. The identification of post-obstructive pulmonary edema as a significant contributor to mortality in these cases emphasizes the need for timely and effective medical interventions to mitigate adverse outcomes in individuals who survive hanging attempts.
Surgical and experimental pathology, Jul 10, 2024
Background Situs inversus is a rare congenital anomaly. In this condition, the abdominal and ches... more Background Situs inversus is a rare congenital anomaly. In this condition, the abdominal and chest organs are positioned in reverse, a mirror image of the normal anatomical position. It is divided into two categories. 1. Situs inversus totalis, in which the apex of the heart points toward the right side. 2. Situs inversus partialis or incompletus, in which the apex of the heart points toward the left side. Situs inversus totalis is present in 1 per 10,000 to 50,000 individuals of the general population, whereas situs inversus partialis is a much rarer condition and is present in 1 per 2,000,000 individuals of the general population. The term situs ambiguous is also used for the arrangement of organs and vessels in an unordered manner. Case presentation In this paper, we present an extraordinary case of situs inversus partialis discovered incidentally during the autopsy of a female body with a documented history of suicidal poisoning. This unique finding sheds light on the diagnostic challenges and implications of situs inversus partialis, especially in patients with underlying medical conditions. Conclusions This report underscores the importance of thorough and systematic investigations during autopsy examinations to identify and comprehend rare anatomical anomalies that may otherwise remain unnoticed. Increased awareness of such rare congenital anomalies may contribute to a better understanding of their prevalence and potential clinical implications for healthcare professionals and researchers.
Elsevier: Toxicology reports
Background: Poisoning is a critical health issue caused by exposure to harmful substances, leadin... more Background: Poisoning is a critical health issue caused by exposure to harmful substances, leading to a range of biological effects from mild irritation to severe organ damage and death. Acute poisoning is particularly prevalent in developing countries reliant on agriculture, where agricultural poisons such as organophosphates, carbamates, pyrethroids, and aluminum/zinc phosphide are common. This study aims to analyze the histopathological changes in various organs in autopsy of poisoning cases to understand the extent and nature of organ damage. Methods: Autopsies were performed on cases with an established or suspected history of poison ingestion. Tissue samples from the stomach, intestine, liver, spleen, kidneys, brain, and lungs were examined for histopathological changes. Results: Out of 52 cases analyzed, aluminum phosphide was the predominant poison, accounting for 76.92 % of cases. Histopathological findings in poisoning cases included significant pulmonary edema (55.77 %), intraalveolar hemorrhage (48.08 %), liver ballooning degeneration (48.08 %), acute tubular necrosis (51.92 %) in kidney, and universal brain and spleen congestion (100 %). Stomach findings showed partial loss of rugosity (80.77 %), congestion (51.92 %), necrosis of the mucosa (30.77 %), congestion (71.15 %), denudation of the epithelium (48.08 %), and mucosal inflammation (48.08 %) as predominant findings. Aluminum phosphide caused severe histopathological changes across all examined organs. Conclusion: The study highlights the critical role of histopathological examination in diagnosing and understanding organ damage in poisoning cases. Forensic pathologists can use these histopathological patterns as reference points to differentiate poisoning from other causes of death, aiding in accurate diagnosis and targeted treatment.
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Papers by Driliyas Sheikh
Aim and Objective: This study aims to investigate cases of delayed death by hanging and analyse the associated pathophysiological mechanisms.
Results: Three cases of delayed death by hanging were identified and analysed in this study. Each case involved individuals who initially survived the suicidal attempts and received medical treatment. Despite efforts, all three individuals succumbed to their injuries after a period of time. Autopsy findings revealed characteristic signs of hanging, along with evidence of post-obstructive pulmonary edema as the cause of death in each case.
Conclusions: This study highlights the occurrence of delayed deaths following suicidal hanging and underscores the importance of understanding the pathophysiological mechanisms involved. The identification of post-obstructive pulmonary edema as a significant contributor to mortality in these cases emphasizes the need for timely and effective medical interventions to mitigate adverse outcomes in individuals who survive hanging attempts.
Aim and Objective: This study aims to investigate cases of delayed death by hanging and analyse the associated pathophysiological mechanisms.
Results: Three cases of delayed death by hanging were identified and analysed in this study. Each case involved individuals who initially survived the suicidal attempts and received medical treatment. Despite efforts, all three individuals succumbed to their injuries after a period of time. Autopsy findings revealed characteristic signs of hanging, along with evidence of post-obstructive pulmonary edema as the cause of death in each case.
Conclusions: This study highlights the occurrence of delayed deaths following suicidal hanging and underscores the importance of understanding the pathophysiological mechanisms involved. The identification of post-obstructive pulmonary edema as a significant contributor to mortality in these cases emphasizes the need for timely and effective medical interventions to mitigate adverse outcomes in individuals who survive hanging attempts.