SULT1E1

SULT1E1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1G3M, 1HY3, 4JVL, 4JVM, 4JVN
Dynodwyr
Cyfenwau	SULT1E1, EST, EST-1, ST1E1, STE, sulfotransferase family 1E member 1
Dynodwyr allanol	OMIM: 600043 HomoloGene: 101388 GeneCards: SULT1E1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • estrone sulfotransferase activity • transferase activity • sulfotransferase activity • steroid binding • steroid sulfotransferase activity • flavonol 3-sulfotransferase activity • GO:0001948, GO:0016582 protein binding • lipid binding • aryl sulfotransferase activity Cydrannau o'r gell • cytoplasm • cytosol • nuclear membrane Prosesau biolegol • steroid metabolic process • positive regulation of fat cell differentiation • estrogen metabolic process • sulfation • ethanol catabolic process • estrogen catabolic process • 3'-phosphoadenosine 5'-phosphosulfate metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6783	n/a
Ensembl	ENSG00000109193	n/a
UniProt	P49888	n/a
RefSeq (mRNA)	NM_005420	n/a
RefSeq (protein)	NP_005411	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SULT1E1 yw SULT1E1 a elwir hefyd yn Sulfotransferase family 1E member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SULT1E1.

• EST
• STE
• EST-1
• ST1E1

Llyfryddiaeth

• "The transition of human estrogen sulfotransferase from generalist to specialist using directed enzyme evolution. ". J Mol Biol. 2012. PMID 22197379.
• "Liganded pregnane X receptor represses the human sulfotransferase SULT1E1 promoter through disrupting its chromatin structure. ". Nucleic Acids Res. 2011. PMID 21764778.
• "In Silico Prediction of Human Sulfotransferase 1E1 Activity Guided by Pharmacophores from Molecular Dynamics Simulations. ". J Biol Chem. 2016. PMID 26542807.
• "New diterpenoids with estrogen sulfotransferase inhibitory activity from Leonurus sibiricus L. ". J Nat Med. 2014. PMID 23736977.
• "Estrogen sulfotransferase (SULT1E1) regulates inflammatory response and lipid metabolism of human endothelial cells via PPARγ.". Mol Cell Endocrinol. 2013. PMID 23384540.