PIGR

PIGR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XED, 2OCW, 3CHN, 3CM9, 5D4K
Dynodwyr
Cyfenwau	PIGR, Pigr, polymeric immunoglobulin receptor
Dynodwyr allanol	OMIM: 173880 HomoloGene: 1984 GeneCards: PIGR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • polymeric immunoglobulin receptor activity Cydrannau o'r gell • integral component of membrane • extracellular region • receptor complex • integral component of plasma membrane • extracellular exosome • bilen • extracellular space • Cellbilen • azurophil granule membrane Prosesau biolegol • Fc receptor signaling pathway • immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor • retina homeostasis • detection of chemical stimulus involved in sensory perception of bitter taste • epidermal growth factor receptor signaling pathway • receptor clustering • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5284	n/a
Ensembl	ENSG00000162896	n/a
UniProt	P01833	n/a
RefSeq (mRNA)	NM_002644	n/a
RefSeq (protein)	NP_002635	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PIGR yw PIGR a elwir hefyd yn Polymeric immunoglobulin receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q32.1.

Llyfryddiaeth

• "Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis. ". PLoS One. 2014. PMID 25397670.
• "Polymeric immunoglobulin receptor expression is correlated with poor prognosis in patients with osteosarcoma. ". Mol Med Rep. 2014. PMID 24699841.
• "Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma. ". Pancreatology. 2017. PMID 28173980.
• "The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins. ". Elife. 2016. PMID 26943617.
• "COLORECTAL Polymeric Immunoglobulin Receptor Expression is Correlated with Hepatic Metastasis and Poor Prognosis in Colon Carcinoma Patients with Hepatic Metastasis.". Hepatogastroenterology. 2014. PMID 26176052.