PAPSS2

PAPSS2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2AX4
Dynodwyr
Cyfenwau	PAPSS2, ATPSK2, BCYM4, SK2, 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Dynodwyr allanol	OMIM: 603005 HomoloGene: 55840 GeneCards: PAPSS2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ATP binding • nucleotidyltransferase activity • kinase activity • catalytic activity • nucleotide binding • transferase activity • sulfate adenylyltransferase (ATP) activity • adenylylsulfate kinase activity Cydrannau o'r gell • cytosol Prosesau biolegol • blood coagulation • skeletal system development • bone development • phosphorylation • metabolaeth • sulfate assimilation • 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9060	n/a
Ensembl	ENSG00000198682	n/a
UniProt	O95340 Q5TB52	n/a
RefSeq (mRNA)	NM_004670 NM_001015880	n/a
RefSeq (protein)	NP_001015880 NP_004661 NP_004661.2	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PAPSS2 yw PAPSS2 a elwir hefyd yn 3'-phosphoadenosine 5'-phosphosulfate synthase 2, isoform CRA_b (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10q23.2-q23.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PAPSS2.

• SK2
• BCYM4
• ATPSK2

Llyfryddiaeth

• "PAPSS2 mutations cause autosomal recessive brachyolmia. ". J Med Genet. 2012. PMID 22791835.
• "Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage. ". Arthritis Res Ther. 2012. PMID 22394585.
• "Gene Expression Differences Between Offspring of Long-Lived Individuals and Controls in Candidate Longevity Regions: Evidence for PAPSS2 as a Longevity Gene. ". J Gerontol A Biol Sci Med Sci. 2016. PMID 26896383.
• "PAPSS2 deficiency causes androgen excess via impaired DHEA sulfation--in vitro and in vivo studies in a family harboring two novel PAPSS2 mutations. ". J Clin Endocrinol Metab. 2015. PMID 25594860.
• "Clinical and radiographic features of the autosomal recessive form of brachyolmia caused by PAPSS2 mutations.". Hum Mutat. 2013. PMID 23824674.