KCNJ3

KCNJ3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1N9P, 1U4E, 2QKS, 3K6N
Dynodwyr
Cyfenwau	KCNJ3, GIRK1, KGA, KIR3.1, potassium voltage-gated channel subfamily J member 3, potassium inwardly rectifying channel subfamily J member 3
Dynodwyr allanol	OMIM: 601534 HomoloGene: 1687 GeneCards: KCNJ3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • G-protein activated inward rectifier potassium channel activity • GO:0001948, GO:0016582 protein binding • inward rectifier potassium channel activity • voltage-gated ion channel activity • voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization • voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Cydrannau o'r gell • integral component of membrane • T-tubule • cell surface • Cellbilen • bilen • external side of plasma membrane • voltage-gated potassium channel complex • parallel fiber to Purkinje cell synapse • integral component of presynaptic membrane Prosesau biolegol • potassium ion transport • regulation of ion transmembrane transport • cludo ïon • response to electrical stimulus • regulation of heart rate by cardiac conduction • membrane repolarization during atrial cardiac muscle cell action potential • membrane repolarization during ventricular cardiac muscle cell action potential • ventricular cardiac muscle cell membrane repolarization • potassium ion import across plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3760	n/a
Ensembl	ENSG00000162989	n/a
UniProt	P48549	n/a
RefSeq (mRNA)	NM_002239 NM_001260508 NM_001260509 NM_001260510	n/a
RefSeq (protein)	NP_001247437 NP_001247438 NP_001247439 NP_002230	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNJ3 yw KCNJ3 a elwir hefyd yn Potassium voltage-gated channel subfamily J member 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KCNJ3.

• KGA
• GIRK1
• KIR3.1

Llyfryddiaeth

• "Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner. ". BMC Cancer. 2016. PMID 27519272.
• "A novel, radiolabel-free pulse chase strategy to study Kir3 channel ontogeny. ". J Recept Signal Transduct Res. 2013. PMID 23368630.
• "Association study of the KCNJ3 gene as a susceptibility candidate for schizophrenia in the Chinese population. ". Hum Genet. 2012. PMID 21927946.
• "G protein {beta}{gamma} gating confers volatile anesthetic inhibition to Kir3 channels. ". J Biol Chem. 2010. PMID 21044958.
• "Cloning and characterisation of GIRK1 variants resulting from alternative RNA editing of the KCNJ3 gene transcript in a human breast cancer cell line.". J Cell Biochem. 2010. PMID 20512921.