DLG2

DLG2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BYG, 2HE2
Dynodwyr
Cyfenwau	DLG2, PPP1R58, PSD-93, PSD93, chapsyn-110, discs large homolog 2, discs large MAGUK scaffold protein 2
Dynodwyr allanol	OMIM: 603583 HomoloGene: 1046 GeneCards: DLG2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • guanylate kinase activity • kinase binding • GO:0001948, GO:0016582 protein binding • ionotropic glutamate receptor binding • structural constituent of postsynaptic density Cydrannau o'r gell • postsynaptic membrane • cell projection • bilen • GO:0097483, GO:0097481 postsynaptic density • voltage-gated potassium channel complex • Cellbilen • synapse • axon • cell junction • basolateral plasma membrane • ionotropic glutamate receptor complex • juxtaparanode region of axon • cytosol • neuromuscular junction • neuron projection • postsynaptic density membrane • glutamatergic synapse • axon cytoplasm Prosesau biolegol • chemical synaptic transmission • receptor localization to synapse • negative regulation of phosphatase activity • receptor clustering • nervous system development • establishment or maintenance of epithelial cell apical/basal polarity • sensory perception of pain • GDP metabolic process • GMP metabolic process • MAPK cascade • cellular response to potassium ion • cell-cell adhesion • maintenance of postsynaptic density structure • anterograde axonal protein transport • retrograde axonal protein transport • neurotransmitter receptor localization to postsynaptic specialization membrane • regulation of NMDA receptor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1740	n/a
Ensembl	ENSG00000150672	n/a
UniProt	Q15700	n/a
RefSeq (mRNA)	NM_001142699 NM_001142700 NM_001142702 NM_001206769 NM_001300983 NM_001364 NM_001351274 NM_001351275 NM_001351276 NM_001377966 NM_001377967 NM_001377968 NM_001377970 NM_001377971 NM_001377972 NM_001377973 NM_001377974 NM_001377975 NM_001377976 NM_001377977 NM_001377978 NM_001377979 NM_001377980 NM_001377981 NM_001377982 NM_001377983 NM_175892	n/a
RefSeq (protein)	NP_001136171 NP_001136172 NP_001136174 NP_001193698 NP_001287912 NP_001355 NP_001338203 NP_001338204 NP_001338205 NP_001364895 NP_001364896 NP_001364897 NP_001364899 NP_001364900 NP_001364901 NP_001364902 NP_001364903 NP_001364904 NP_001364905 NP_001364906 NP_001364907 NP_001364908 NP_001364909 NP_001364910 NP_001364911 NP_001364912	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DLG2 yw DLG2 a elwir hefyd yn Disks large homolog 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q14.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DLG2.

• PSD93
• PSD-93
• PPP1R58
• chapsyn-110

Llyfryddiaeth

• "Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy. ". Acta Crystallogr D Biol Crystallogr. 2013. PMID 23519667.
• "Structure of the first PDZ domain of human PSD-93. ". Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID 20054121.
• "Evaluation of DLG2 as a positional candidate for disposition index in African-Americans from the IRAS Family Study. ". Diabetes Res Clin Pract. 2010. PMID 19931931.
• "Differential expression of a new isoform of DLG2 in renal oncocytoma. ". BMC Cancer. 2006. PMID 16640776.
• "Expression, regulation and role of the MAGUK protein SAP-97 in human atrial myocardium.". Cardiovasc Res. 2002. PMID 12445884.