High expression of proline-rich tyrosine kinase 2 is associated with poor survival of hepatocellular carcinoma via regulating phosphatidylinositol 3-kinase/AKT pathway. (Q54308665)

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scientific article published on 23 May 2012

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English	High expression of proline-rich tyrosine kinase 2 is associated with poor survival of hepatocellular carcinoma via regulating phosphatidylinositol 3-kinase/AKT pathway.	scientific article published on 23 May 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

High expression of proline-rich tyrosine kinase 2 is associated with poor survival of hepatocellular carcinoma via regulating phosphatidylinositol 3-kinase/AKT pathway. (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

author name string

Jie Cao

1

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Yao Chen

2

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27 May 2018

http://europepmc.org/abstract/MED/22618716

Jing Fu

3

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PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

You-Wen Qian

4

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Yi-Bin Ren

5

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Bo Su

6

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Tao Luo

7

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Rong-Yang Dai

8

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27 May 2018

http://europepmc.org/abstract/MED/22618716

Liang Huang

9

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PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Jian-Jun Yan

10

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27 May 2018

http://europepmc.org/abstract/MED/22618716

Meng-Chao Wu

11

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PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Yi-Qun Yan

12

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Hong-Yang Wang

13

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27 May 2018

http://europepmc.org/abstract/MED/22618716

publication date

23 May 2012

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Annals of Surgical Oncology

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27 May 2018

http://europepmc.org/abstract/MED/22618716

20 Suppl 3

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27 May 2018

http://europepmc.org/abstract/MED/22618716

S312-23

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PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Hepatocellular carcinoma pathogenesis: from genes to environment

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

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21 January 2018

Oncogenic kinase signalling

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21 January 2018

The tyrosine kinase pyk2 promotes migration and invasion of glioma cells.

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Pyk2/CAKbeta tyrosine kinase activity-mediated angiogenesis of pulmonary vascular endothelial cells

1 reference

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Proline-rich tyrosine kinase 2 regulates proliferation and differentiation of prostate cells

1 reference

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21 January 2018

Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness

1 reference

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21 January 2018

The significance of proline-rich tyrosine kinase2 (Pyk2) on hepatocellular carcinoma progression and recurrence.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

2-Methoxyestradiol exhibits a biphasic effect on VEGF-A in tumor cells and upregulation is mediated through ER-alpha: a possible signaling pathway associated with the impact of 2-ME2 on proliferative cells

1 reference

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21 January 2018

Autocrine signaling in carcinoma: VEGF and the alpha6beta4 integrin

1 reference

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21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Targeting the phosphoinositide 3-kinase pathway in cancer

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2.

1 reference

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21 January 2018

Vascular endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and related adhesion focal tyrosine kinase

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Expression analysis of protein tyrosine kinases of the FAK (focal adhesion kinase) family in osteosarcoma

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Variations of proline-rich kinase Pyk2 expression correlate with prostate cancer progression

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Specific gene-expression profiles of noncancerous liver tissue predict the risk for multicentric occurrence of hepatocellular carcinoma in hepatitis C virus-positive patients

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Human endothelial Pyk2 is expressed in two isoforms and associates with paxillin and p130Cas

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Protein-tyrosine kinase Pyk2 is involved in interleukin-2 production by Jurkat T cells via its tyrosine 402

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

The tyrosine kinase Pyk2 mediates lipopolysaccharide-induced IL-8 expression in human endothelial cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Targeting transforming growth factor (TGF)-betaRI inhibits activation of beta1 integrin and blocks vascular invasion in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Targeting Pyk2 for therapeutic intervention

1 reference

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21 January 2018

Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

1 reference

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21 January 2018

Association between vascular endothelial growth factor gene polymorphisms and survival in hepatocellular carcinoma patients

1 reference

https://api.crossref.org/works/10.1245%2FS10434-012-2372-9

21 January 2018

Identifiers

10.1245/S10434-012-2372-9

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/22618716

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