p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells (Q40918524)

24 September 2017

title

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells (English)

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24 September 2017

Sutterlüty H

1

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24 September 2017

Chatelain E

2

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24 September 2017

Marti A

3

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24 September 2017

Wirbelauer C

4

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24 September 2017

Senften M

5

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24 September 2017

Müller U

6

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24 September 2017

Krek W

7

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24 September 2017

publication date

1 August 1999

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24 September 2017

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24 September 2017

volume

1

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24 September 2017

issue

4

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24 September 2017

page(s)

207-214

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Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle

24 September 2017

cites work

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7 January 2021

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7 January 2021

Rules to replicate by

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7 January 2021

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

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7 January 2021

Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication

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7 January 2021

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

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7 January 2021

Cyclin A is required at two points in the human cell cycle

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7 January 2021

Cyclin A is required in S phase in normal epithelial cells.

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7 January 2021

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

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7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

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7 January 2021

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

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7 January 2021

Cyclin A-associated kinase activity is rate limiting for entrance into S phase and is negatively regulated in G1 by p27Kip1.

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7 January 2021

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

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7 January 2021

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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7 January 2021

How the cyclin became a cyclin: regulated proteolysis in the cell cycle

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7 January 2021

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

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7 January 2021

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

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7 January 2021

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

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7 January 2021

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

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7 January 2021

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

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7 January 2021

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

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7 January 2021

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

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7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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7 January 2021

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

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7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

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7 January 2021

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1

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7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

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7 January 2021

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

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7 January 2021

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

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7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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7 January 2021

The MYC protein activates transcription of the alpha-prothymosin gene.

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7 January 2021

G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts

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7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

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7 January 2021

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

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7 January 2021

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

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7 January 2021

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

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7 January 2021

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

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7 January 2021

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

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7 January 2021

Application of novel vectors for GFP-tagging of proteins to study microtubule-associated proteins

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7 January 2021

Identifiers

DOI

10.1038/12027

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Dimensions Publication ID

24 September 2017

1033906773

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