Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation. (Q39880179)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240026%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation (English)

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22 January 2020

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2

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22 January 2020

author name string

Satoshi Nemoto

1

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22 January 2020

Yosuke Osawa

3

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22 January 2020

Saki Kono

4

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22 January 2020

Yoshinori Itoh

5

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22 January 2020

Yukio Okano

6

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22 January 2020

Takashi Murate

7

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22 January 2020

Akira Hara

8

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22 January 2020

Hiroshi Ueda

9

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22 January 2020

Yoshinori Nozawa

10

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22 January 2020

Yoshiko Banno

11

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22 January 2020

language of work or name

English

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publication date

24 February 2009

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22 January 2020

number of pages

11

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Journal of Biological Chemistry

inferred from page(s)

published in

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22 January 2020

volume

284

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22 January 2020

issue

16

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22 January 2020

page(s)

10422-10432

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Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells

22 January 2020

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(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1

22 September 2017

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High expression of sphingosine kinase 1 and S1P receptors in chemotherapy-resistant prostate cancer PC3 cells and their camptothecin-induced up-regulation

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22 September 2017

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Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines

22 September 2017

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Role of sphingosine kinase 2 in cell migration toward epidermal growth factor

22 September 2017

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Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha

22 September 2017

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Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway

22 September 2017

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Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells.

22 September 2017

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Ceramide reduction and transcriptional up-regulation of glucosylceramide synthase through doxorubicin-activated Sp1 in drug-resistant HL-60/ADR cells

22 September 2017

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Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas

22 September 2017

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Biologically active sphingolipids in cancer pathogenesis and treatment

22 September 2017

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22 September 2017

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Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

22 September 2017

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22 September 2017

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Up-regulation of acid sphingomyelinase during retinoic acid-induced myeloid differentiation of NB4, a human acute promyelocytic leukemia cell line

22 September 2017

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TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes

25 September 2017

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Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

25 September 2017

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Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

25 September 2017

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Ceramide generation in nitric oxide-induced apoptosis. Activation of magnesium-dependent neutral sphingomyelinase via caspase-3.

25 September 2017

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25 September 2017

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25 September 2017

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Sphingosine kinase 1 is involved in dibutyryl cyclic AMP-induced granulocytic differentiation through the upregulation of extracellular signal-regulated kinase, but not p38 MAP kinase, in HL60 cells

17 June 2018

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17 June 2018

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Combination of C(17) sphingoid base homologues and mass spectrometry analysis as a new approach to study sphingolipid metabolism

17 June 2018

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20 August 2018

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Chemoradiation of cervical cancer cells: targeting human papillomavirus E6 and p53 leads to either augmented or attenuated apoptosis depending on the platinum carrier ligand.

20 August 2018

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Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells

20 August 2018

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12 December 2020

cis-4-Methylsphingosine decreases sphingolipid biosynthesis by specifically interfering with serine palmitoyltransferase activity in primary cultured neurons

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12 December 2020

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

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12 December 2020

Quantitative RT-PCR analysis of sphingolipid metabolic enzymes in acute leukemia and myelodysplastic syndromes

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12 December 2020

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells

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12 December 2020

Identifiers

DOI

10.1074/JBC.M900735200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240026%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240026%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

19240026

1 reference