The decline and fall of the IGF-I receptor (Q38038480)

27 August 2017

title

The decline and fall of the IGF-I receptor (English)

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27 August 2017

Renato Baserga

1

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27 August 2017

publication date

1 April 2013

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Journal of Cellular Physiology

27 August 2017

published in

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27 August 2017

volume

228

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27 August 2017

issue

4

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27 August 2017

page(s)

675-679

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Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells

27 August 2017

cites work

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The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicity

21 January 2018

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Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas

21 January 2018

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The contradictions of the insulin-like growth factor 1 receptor

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The insulin-like growth factor-I receptor as a target for cancer therapy

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The insulin receptor substrate-1: a biomarker for cancer?

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The IGF‐1 receptor in cancer biology

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Drug development: Raise standards for preclinical cancer research

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The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer.

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Silencing of the insulin receptor isoform A favors formation of type 1 insulin-like growth factor receptor (IGF-IR) homodimers and enhances ligand-induced IGF-IR activation and viability of human colon carcinoma cells.

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Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors

21 January 2018

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Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer

21 January 2018

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Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

21 January 2018

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Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA

21 January 2018

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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

21 January 2018

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21 January 2018

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21 January 2018

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

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Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.

21 January 2018

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Dynamics of cancer cell subpopulations in primary and metastatic colorectal tumors

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Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

21 January 2018

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Molecular Analysis of Non–Small Cell Lung Cancer Identifies Subsets with Different Sensitivity to Insulin-like Growth Factor I Receptor Inhibition

21 January 2018

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Why most published research findings are false

21 January 2018

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Tumours with PI3K activation are resistant to dietary restriction

21 January 2018

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Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

21 January 2018

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

21 January 2018

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Mechanism of growth inhibition by MicroRNA 145: the role of the IGF-I receptor signaling pathway

21 January 2018

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Role of insulin-like growth factor 1 receptor signalling in cancer

21 January 2018

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21 January 2018

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Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

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Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

21 January 2018

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Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study

21 January 2018

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The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology

21 January 2018

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Heterogeneity in breast cancer

21 January 2018

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The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival.

21 January 2018

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Beware the creeping cracks of bias.

21 January 2018

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SUMOylation mediates the nuclear translocation and signaling of the IGF-1 receptor

21 January 2018

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

21 January 2018

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

21 January 2018

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Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells

21 January 2018

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Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

21 January 2018

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Normal growth and development in the absence of hepatic insulin-like growth factor I

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.24217

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27 August 2017

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