Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose (Q36599646)

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2 March 2020

title

Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose (English)

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2 March 2020

2

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2 March 2020

John Challiss

5

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2 March 2020

Richard D Rainbow

8

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2 March 2020

author name string

Robert Jackson

1

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2 March 2020

Peter Fielding

3

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2 March 2020

Mark W Sims

4

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2 March 2020

David Adlam

6

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2 March 2020

Iain B Squire

7

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2 March 2020

language of work or name

English

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publication date

8 February 2016

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British Journal of Pharmacology

2 March 2020

published in

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2 March 2020

volume

173

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2 March 2020

issue

5

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2 March 2020

page(s)

870-887

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The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

2 March 2020

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Regulation of intracerebral arteriolar tone by K(v) channels: effects of glucose and PKC.

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Impact of glucose concentration on cardiac ventricular repolarization under I Kr/I Ks blocking agents

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High glucose increases the expression of Gq/11alpha and PLC-beta proteins and associated signaling in vascular smooth muscle cells

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Physiological roles of K+ channels in vascular smooth muscle cells

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Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol kinase subcellular localization.

30 September 2017

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Protein kinase C beta inhibition: A novel therapeutic strategy for diabetic microangiopathy

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Preclinical and clinical development of novel agents that target the protein kinase C family

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Increased contractile responses to 5-Hydroxytryptamine and Angiotensin II in high fat diet fed rat thoracic aorta

30 September 2017

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Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC.

30 September 2017

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Arteriolar nitric oxide concentration is decreased during hyperglycemia-induced betaII PKC activation

30 September 2017

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Mechanisms underlying endothelial dysfunction in diabetes mellitus

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Vascular effects of acute hyperglycemia in humans are reversed by L-arginine. Evidence for reduced availability of nitric oxide during hyperglycemia

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Glucose-induced alterations of cytosolic free calcium in cultured rat tail artery vascular smooth muscle cells

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Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications

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Regulation of 4-aminopyridine-sensitive, delayed rectifier K+ channels in vascular smooth muscle by phosphorylation

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Calcium homeostasis in vascular smooth muscle cells is altered in type 2 diabetes by Bcl-2 protein modulation of InsP3R calcium release channels

20 September 2018

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20 September 2018

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Prognostic value of admission blood glucose concentration and diabetes diagnosis on survival after acute myocardial infarction: results from 4702 index cases in routine practice

20 September 2018

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20 September 2018

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Acute hyperglycemia and hyperinsulinemia enhance adrenergic vasoconstriction and decrease calcitonin gene-related peptide-containing nerve-mediated vasodilation in pithed rats.

20 September 2018

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Glucometrics in patients hospitalized with acute myocardial infarction: defining the optimal outcomes-based measure of risk

20 September 2018

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20 September 2018

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High glucose concentration augments angiotensin II mediated contraction via AT1 receptors in rat thoracic aorta

20 September 2018

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Novel diacylglycerol kinase inhibitor selectively suppressed an U46619-induced enhancement of mouse portal vein contraction under high glucose conditions

20 September 2018

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Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells

20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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High glucose impairs voltage-gated K(+) channel current in rat small coronary arteries

20 September 2018

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20 September 2018

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Prognostic significance of the change in glucose level in the first 24 h after acute myocardial infarction: results from the CARDINAL study

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Crossref

https://api.crossref.org/works/10.1111%2FBPH.13399

Glucose reduces endothelin inhibition of voltage-gated potassium channels in rat arterial smooth muscle cells

21 January 2018

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12 December 2020

Key role of Kv1 channels in vasoregulation

1 reference

12 December 2020

Effect of intracoronary serotonin on coronary vessels in patients with stable angina and patients with variant angina

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12 December 2020

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

1 reference

12 December 2020

Acute hyperglycaemia causes severe disturbances of mesenteric microcirculation in an in vivo rat model

1 reference

12 December 2020

Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues

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12 December 2020

Acute hyperglycaemia disturbs cardiac repolarization in Type 1 diabetes

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Coronary artery infusion of neuropeptide Y in patients with angina pectoris

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Voltage-gated K+ channels in rat small cerebral arteries: molecular identity of the functional channels

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Identifiers

DOI

10.1111/BPH.13399

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26660275%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26660275%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

26660275

1 reference