Big physics, small doses: the use of AMS and PET in human microdosing of development drugs (Q35075780)

6 August 2017

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title

Big physics, small doses: the use of AMS and PET in human microdosing of development drugs (English)

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6 August 2017

Graham Lappin

1

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6 August 2017

R Colin Garner

series ordinal

2

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6 August 2017

publication date

1 March 2003

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Nature Reviews Drug Discovery

6 August 2017

published in

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6 August 2017

volume

2

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6 August 2017

issue

3

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6 August 2017

page(s)

233-240

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Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985)

6 August 2017

cites work

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Pharmacokinetic evaluation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in patients by positron emission tomography

21 January 2018

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Evaluation of accelerator mass spectrometry in a human mass balance and pharmacokinetic study-experience with 14C-labeled (R)-6-[amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a far

21 January 2018

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PET for in vivo pharmacokinetic and pharmacodynamic measurements

21 January 2018

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Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans

21 January 2018

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From the analyst's couch. Trends in development cycles

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Risks in new drug development: approval success rates for investigational drugs

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In vivo pharmacokinetics and pharmacodynamics in drug development using positron-emission tomography

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21 January 2018

Identifiers

DOI

10.1038/NRD1037

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6 August 2017

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