Neurofibromatosis 1: closing the GAP between mice and men. (Q35062427)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12573431%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

review article

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title

Neurofibromatosis 1: closing the GAP between mice and men (English)

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18 December 2019

2

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18 December 2019

author name string

Biplab Dasgupta

series ordinal

1

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18 December 2019

publication date

1 February 2003

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Current Opinion in Genetics & Development

18 December 2019

published in

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18 December 2019

volume

13

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18 December 2019

issue

1

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18 December 2019

page(s)

20-27

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Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force.

18 December 2019

cites work

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Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders

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Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes

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Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

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Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells

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Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

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Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

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Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

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Pituitary adenylate cyclase activating polypeptide (PACAP) stimulates mitogen-activated protein kinase (MAPK) in cultured rat astrocytes

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Neurofibromin regulates G protein-stimulated adenylyl cyclase activity

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A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK.

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Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1

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Tumorigenic properties of neurofibromin-deficient neurofibroma Schwann cells

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NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors

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Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas

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Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas

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7 January 2021

Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models

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7 January 2021

Nf1 and Gmcsf interact in myeloid leukemogenesis

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7 January 2021

Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.

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7 January 2021

Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.

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Loss of NF1 alleles distinguish sporadic from NF1-associated pilocytic astrocytomas.

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7 January 2021

Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects

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7 January 2021

Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines

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7 January 2021

Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

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7 January 2021

Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes

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7 January 2021

Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro

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7 January 2021

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

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7 January 2021

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

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7 January 2021

Neurofibromas in NF1: Schwann cell origin and role of tumor environment

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7 January 2021

Mouse models of tumor development in neurofibromatosis type 1

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7 January 2021

Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

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7 January 2021

Mouse tumor model for neurofibromatosis type 1

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7 January 2021

Loss of neurofibromatosis-1 and p19(ARF) cooperate to induce a multiple tumor phenotype

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7 January 2021

Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

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7 January 2021

Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1

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7 January 2021

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12573431%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

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