Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. (Q34563234)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16951254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

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title

Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression (English)

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29 December 2019

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6

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29 December 2019

8

Stanley J Korsmeyer

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29 December 2019

author name string

Shugaku Takeda

1

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29 December 2019

David Y Chen

2

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29 December 2019

Todd D Westergard

3

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29 December 2019

Jill K Fisher

4

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29 December 2019

Jeffrey A Rubens

5

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29 December 2019

Jason T Kan

7

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29 December 2019

Emily H-Y Cheng

9

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29 December 2019

James J-D Hsieh

10

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29 December 2019

language of work or name

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1 September 2006

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29 December 2019

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29 December 2019

volume

20

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29 December 2019

issue

17

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29 December 2019

page(s)

2397-2409

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Uncleaved TFIIA is a substrate for taspase 1 and active in transcription

29 December 2019

cites work

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Crystal structure of human Taspase1, a crucial protease regulating the function of MLL.

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The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression

7 July 2018

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Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

7 July 2018

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WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development

7 July 2018

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MLL: how complex does it get?

7 July 2018

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Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

7 July 2018

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7 July 2018

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7 July 2018

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Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging.

7 July 2018

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Hitting their targets: an emerging picture of E2F and cell cycle control

7 July 2018

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7 July 2018

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Cleavage and proteasome-mediated degradation of the basal transcription factor TFIIA.

7 July 2018

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Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

7 July 2018

1 reference

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Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis

7 July 2018

1 reference

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Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

7 July 2018

1 reference

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ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia

7 July 2018

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Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

7 July 2018

1 reference

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Cyclin E ablation in the mouse

7 July 2018

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Organizing axes in time and space; 25 years of colinear tinkering

7 July 2018

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Proteolytic processing is necessary to separate and ensure proper cell growth and cytokinesis functions of HCF-1

7 July 2018

1 reference

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Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

7 July 2018

1 reference

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ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

7 July 2018

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MLL targets SET domain methyltransferase activity to Hox gene promoters

7 July 2018

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Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties

7 July 2018

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Active genes are tri-methylated at K4 of histone H3

7 July 2018

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Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6.

7 July 2018

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Sibling rivalry in the E2F family

7 July 2018

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Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

7 July 2018

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Regulation of cellular senescence by p53.

7 July 2018

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The Rb/E2F pathway and cancer

7 July 2018

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Proteolysis and developmental signal transduction

7 July 2018

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

7 July 2018

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MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines

7 July 2018

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Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

7 July 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

7 July 2018

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Mutant alleles of the Drosophila trithorax gene produce common and unusual homeotic and other developmental phenotypes.

7 July 2018

1 reference

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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

7 July 2018

1 reference

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MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis

7 July 2018

1 reference

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7 July 2018

Caspases: enemies within

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The regulation of E2F by pRB-family proteins

7 July 2018

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Hox genes and mammalian development.

7 July 2018

1 reference

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Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription

7 July 2018

1 reference

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Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex

7 July 2018

1 reference

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A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA

7 July 2018

1 reference

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Inducible gene targeting in mice

7 July 2018

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Altered Hox expression and segmental identity in Mll-mutant mice

7 July 2018

1 reference

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The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains

7 July 2018

1 reference

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Homeobox genes and axial patterning

7 July 2018

1 reference

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Expression of leukemic MLL fusion proteins in Drosophila affects cell cycle control and chromosome morphology.

7 July 2018

1 reference

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Mouse development and cell proliferation in the absence of D-cyclins.

27 October 2018

1 reference

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Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene

27 October 2018

1 reference

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The critical role of chromosome translocations in human leukemias.

27 October 2018

1 reference

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27 October 2018

Identifiers

DOI

10.1101/GAD.1449406

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16951254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16951254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

16951254

1 reference