Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists (Q33784491)

29 July 2017

title

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists (English)

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29 July 2017

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Ekambar R Kandimalla

1

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29 July 2017

Lakshmi Bhagat

2

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29 July 2017

Yukui Li

3

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29 July 2017

Dong Yu

4

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29 July 2017

Daqing Wang

5

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29 July 2017

Yan-Ping Cong

6

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29 July 2017

Sam S Song

7

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29 July 2017

Jimmy X Tang

8

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29 July 2017

Tim Sullivan

9

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29 July 2017

Sudhir Agrawal

10

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29 July 2017

language of work or name

English

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publication date

28 April 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

102

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29 July 2017

issue

19

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29 July 2017

page(s)

6925-6930

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Immunotherapeutic uses of CpG oligodeoxynucleotides

29 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1100782

Novel immunomodulatory oligonucleotides prevent development of allergic airway inflammation and airway hyperresponsiveness in asthma

4 July 2018

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A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1100782

CpG oligonucleotides with modified termini and nicked dumbbell structure show enhanced immunostimulatory activity

4 July 2018

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Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells

4 July 2018

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Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells

4 July 2018

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Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles

4 July 2018

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Interleukin 12 immunotherapy after autologous stem cell transplantation for hematological malignancies.

4 July 2018

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'Immunomers'--novel 3'-3'-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents

4 July 2018

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Conjugation of ligands at the 5'-end of CpG DNA affects immunostimulatory activity

4 July 2018

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Antisense and/or immunostimulatory oligonucleotide therapeutics

4 July 2018

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Immunostimulatory properties of phosphorothioate CpG DNA containing both 3'-5'- and 2'-5'-internucleotide linkages

4 July 2018

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Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

4 July 2018

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A Toll-like receptor recognizes bacterial DNA

4 July 2018

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Site of chemical modifications in CpG containing phosphorothioate oligodeoxynucleotide modulates its immunostimulatory activity

4 July 2018

1 reference

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Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.

4 July 2018

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Macrophages ingest and are activated by bacterial DNA.

4 July 2018

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Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

4 July 2018

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CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

4 July 2018

1 reference

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CpG motifs in bacterial DNA trigger direct B-cell activation

4 July 2018

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Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity

4 July 2018

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In vitro augmentation of natural killer cell activity and production of interferon-alpha/beta and -gamma with deoxyribonucleic acid fraction from Mycobacterium bovis BCG.

4 July 2018

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4 July 2018

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Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA.

4 July 2018

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Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions

4 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501729102

Design, synthesis, and immunostimulatory properties of CpG DNAs containing alkyl-linker substitutions: role of nucleosides in the flanking sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501729102

Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501729102

Potent CpG oligonucleotides containing phosphodiester linkages: in vitro and in vivo immunostimulatory properties.

21 January 2018

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Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs.

21 January 2018

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Accessible 5'-end of CpG-containing phosphorothioate oligodeoxynucleotides is essential for immunostimulatory activity

30 October 2018

1 reference

12 December 2020

Modulation of immunostimulatory activity of CpG oligonucleotides by site-specific deletion of nucleobases

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12 December 2020

Immunostimulatory activity of CpG oligonucleotides containing non-ionic methylphosphonate linkages

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12 December 2020

Effect of different chemically modified oligodeoxynucleotides on immune stimulation

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12 December 2020

Pattern and Kinetics of Cytokine Production Following Administration of Phosphorothioate Oligonucleotides in Mice

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12 December 2020

Requirement of nucleobase proximal to CpG dinucleotide for immunostimulatory activity of synthetic CpG DNA

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12 December 2020

CpG penta- and hexadeoxyribonucleotides as potent immunomodulatory agents

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12 December 2020

Immunostimulatory activity of CpG containing phosphorothioate oligodeoxynucleotide is modulated by modification of a single deoxynucleoside

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0501729102

1 reference

29 July 2017

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29 July 2017

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