Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3 (Q28582315)

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English	Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3	scientific journal article

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scholarly article

1 reference

PubMed publication ID

31 January 2017

Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3 (English)

1 reference

PubMed publication ID

31 January 2017

G protein-coupled receptor

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Takehiko Yokomizo

object named as

T. Yokomizo

3

0 references

author name string

H. Okamoto

1

1 reference

PubMed publication ID

31 January 2017

N. Takuwa

2

1 reference

PubMed publication ID

31 January 2017

N. Sugimoto

4

1 reference

PubMed publication ID

31 January 2017

S. Sakurada

5

1 reference

PubMed publication ID

31 January 2017

H. Shigematsu

6

1 reference

PubMed publication ID

31 January 2017

Y. Takuwa

7

1 reference

PubMed publication ID

31 January 2017

language of work or name

0 references

publication date

1 December 2000

1 reference

PubMed publication ID

31 January 2017

Molecular and Cellular Biology

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PubMed publication ID

31 January 2017

20

1 reference

PubMed publication ID

31 January 2017

24

1 reference

PubMed publication ID

31 January 2017

9247–9261

1 reference

PubMed publication ID

31 January 2017

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8

1 reference

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Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5

1 reference

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Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

1 reference

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17 March 2017

Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

1 reference

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17 March 2017

EPS8 and E3B1 transduce signals from Ras to Rac

1 reference

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17 March 2017

Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins

1 reference

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17 March 2017

Comparison of intrinsic activities of the putative sphingosine 1-phosphate receptor subtypes to regulate several signaling pathways in their cDNA-transfected Chinese hamster ovary cells

1 reference

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17 March 2017

Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5

1 reference

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Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218

1 reference

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EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

1 reference

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Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase

1 reference

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17 March 2017

EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio

1 reference

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17 March 2017

Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

1 reference

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17 March 2017

Rho GTPases and the Actin Cytoskeleton

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17 March 2017

Rho GTPases and signaling networks

1 reference

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A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

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Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9

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17 March 2017

Cell migration: a physically integrated molecular process

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

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17 March 2017

Identification of a mouse p21Cdc42/Rac activated kinase

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17 March 2017

An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors

1 reference

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17 March 2017

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

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17 March 2017

The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts

1 reference

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7 April 2017

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1 reference

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7 April 2017

Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator

1 reference

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29 September 2017

Molecular identification and characterization of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate

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29 September 2017

Functions of a new family of sphingosine-1-phosphate receptors

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29 September 2017

Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.

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29 September 2017

Life on the edg.

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29 September 2017

Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

29 September 2017

Bioactive lysophospholipids and their G protein-coupled receptors

1 reference

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29 September 2017

Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?

1 reference

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29 September 2017

A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs).

1 reference

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29 September 2017

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

1 reference

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29 September 2017

Sphingosine 1-phosphate: a prototype of a new class of second messengers.

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29 September 2017

Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate

1 reference

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29 September 2017

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts

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29 September 2017

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

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29 September 2017

Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

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29 September 2017

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

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29 September 2017

A role for Cdc42 in macrophage chemotaxis

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29 September 2017

Inhibition of chemotactic motility and trans‐endothelial migration of human neutrophils by sphingosine 1‐phosphate

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29 September 2017

Receptors induce chemotaxis by releasing the βγ subunit of G i , not by activating G q or G s

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29 September 2017

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

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29 September 2017

Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways.

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29 September 2017

Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling

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Moving membrane up to the front of migrating cells

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29 September 2017

Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction

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29 September 2017

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Potentiation of cell migration by adhesion-dependent cooperative signals from the GTPase Rac and Raf kinase

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3 June 2018

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1 reference

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3 June 2018

Sphingosine-1-phosphate as an intercellular signaling molecule.

1 reference

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3 June 2018

Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

3 June 2018

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1 reference

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3 June 2018

Involvement of Phosphatidylinositide 3′-Kinase and Rac in Platelet-Derived Growth Factor-Induced Actin Reorganization and Chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

3 June 2018

Signaling Mechanisms in Growth Factor‐Stimulated Cell Motility

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3 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

3 June 2018

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1 reference

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3 June 2018

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

3 June 2018

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

3 June 2018

The regulation of endothelial cell motility by p21 ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

3 June 2018

Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102182

3 June 2018

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

1 reference

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3 June 2018

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3 June 2018

Erratum: Close encounters of the LIM-kinase

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

Measurement of intrinsic nucleotide exchange and GTP hydrolysis rates.

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27 November 2018

Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human granulocytes contain an opiate alkaloid-selective receptor mediating inhibition of cytokine-induced activation and chemotaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of murine lymphocyte functions by sulfated cholecystokinin octapeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary adenylate cyclase-activating polypeptide (PACAP38) modulates lymphocyte and macrophage functions: stimulation of adherence and opposite effect on mobility

1 reference

https://pubmed.ncbi.nlm.nih.gov/11094076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.20.24.9247-9261.2000

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Consolidated OpenCitations Corpus – April 2017

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1 reference

Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

1 reference

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