streptonigrin (Q15427845)

streptonigrin (English)

3 October 2016

chemical formula

C₂₅H₂₂N₄O₈

1 reference

streptonigrin (English)

3 October 2016

canonical SMILES

CC1=C(C(=C(N=C1C(=O)O)C2=NC3=C(C=C2)C(=O)C(=C(C3=O)N)OC)N)C4=C(C(=C(C=C4)OC)OC)O

0 references

found in taxon

Streptomyces flocculus

4 references

Streptonigrin biosynthesis. 2. The isolation of β-methyltryptophan and its intermediacy in the streptonigrin pathway

Streptonigrin biosynthesis. 8. Evidence for the involvement of a new shikimate pathway product and a new route to quinolines

A tryptophan C-methyltransferase involved in streptonigrin biosynthesis in Streptomyces flocculus

<b>The Structure of Streptonigrin</b>

Streptomyces

2 references

Biological properties of streptonigrin derivatives. I. Antimicrobial and cytocidal activities

The structure of streptonigrone, and a comment on the biosynthesis of the streptonigrin antibiotics.

Streptomyces albus

4 references

Streptonigrin biosynthesis. 2. The isolation of β-methyltryptophan and its intermediacy in the streptonigrin pathway

A tryptophan C-methyltransferase involved in streptonigrin biosynthesis in Streptomyces flocculus

Streptonigrin biosynthesis. 8. Evidence for the involvement of a new shikimate pathway product and a new route to quinolines

<b>The Structure of Streptonigrin</b>

Micromonospora

1 reference

Isolation of streptonigrin and its novel derivative from Micromonospora as inducing agents of p53-dependent cell apoptosis

subject has role

antineoplastic antibiotics

1 reference

Medical Subject Headings

MeSH descriptor ID

D013308

InChI=1S/C25H22N4O8/c1-9-14(10-6-8-13(35-2)23(36-3)20(10)30)15(26)19(29-17(9)25(33)34)12-7-5-11-18(28-12)22(32)16(27)24(37-4)21(11)31/h5-8,30H,26-27H2,1-4H3,(H,33,34)

15 March 2018

Identifiers

InChI

0 references

3 references

ChEBI release 2020-09-01

Natural Product Atlas

PubChem CID

5298

https://chem.nlm.nih.gov/chemidplus/rn/3930-19-6

2 references

https://commonchemistry.cas.org/detail?cas_rn=3930-19-6

9 April 2021

2 references

Reaxys registry number

599390

0 references

Gmelin number

1240693

0 references

ChEBI ID

9287

mapping relation type

exact match

1 reference

International Chemical Identifier

InChI

InChI=1S/C25H22N4O8/c1-9-14(10-6-8-13(35-2)23(36-3)20(10)30)15(26)19(29-17(9)25(33)34)12-7-5-11-18(28-12)22(32)16(27)24(37-4)21(11)31/h5-8,30H,26-27H2,1-4H3,(H,33,34)

SureChEMBL ID

SCHEMBL3940

2 references

1 reference

NMRShiftDB structure ID

2501

1 reference

20180722

1 reference

DSSTox substance ID

DTXSID00960034

1 reference

DSSTOX compound identifier

0 references

0 references

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.021.366

27 December 2018

ECHA Substance Infocard ID

Rufocromomycin (English)

quotation

CAS no.: 3930-19-6 (English)

100.021.366

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.021.366

27 December 2018

Guide to Pharmacology Ligand ID

Rufocromomycin (English)

quotation

CAS no.: 3930-19-6 (English)

8683

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8683

Human Metabolome Database ID

streptonigrin (English)

3 October 2016

Streptonigrin

0 references

MeSH tree code

D03.066.707.768

0 references

D03.383.725.705.768

0 references

HMDB0258512

2 references

KNApSAcK ID

C00026485

2 references

UNII

261Q3JB310

1 reference

Natural Product Atlas ID

NPA002378

2 references