Scribd Logo
Upload

Welcome to Scribd!

  • 7 views

    Adipose Tissue

    Uploaded by

    mariam.demloj

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd

    Adipose Tissue

    Uploaded by

    mariam.demloj
    7 views13 pages

    Copyright

    © © All Rights Reserved

    Available Formats

    PPT, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    7 views13 pages

    Adipose Tissue

    Uploaded by

    mariam.demloj

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    of 13

    Adipose Tissue

    A. Prof. Dr Ruzanna
    MD,
    MSc.
    References

    Jonquiere's Basic
    Histology
    P. 122-123; 125-127
    LEARNING OBJECTIVES

    - Understand that the adipose tissue is a


    specific connective tissue.
    - Differentiate between adipose tissue and the
    other types of connective tissue.
    Identify adipocyte cells.
    Differentiate between white adipose tissue and
    brown adipose tissue
     Specialized type of connective tissue
     Adipocytes or fat cells predominate
     Cells can be found isolated or in groups
     Adipose tissue represents 15–20% of the body weight in men
    20–25% of body weight in women
    Key regulators of the body’s energy metabolism
    • Adipose tissue is the largest repository of energy (in
    the form of triglycerides) in the body.
    • Adipocytes themselves release hormones and a
    number of important factors
    • Adipose tissue is a poor heat conductor and it
    contributes to the thermal insulation of the body
    • Adipose tissue also fills up spaces between other
    tissues and helps to keep some organs in place
    White Adipose Tissue
    • White adipose cells are spherical or polyhedral
    • Each cell contains one huge droplet of lipid
    • White adipocytes are called unilocular
    • The large droplet causes these cells to have eccentric and flattened nuclei
    The cytoplasm contains a
    Golgi apparatus,
    mitochondria, poorly
    developed rough ER,
    and free polyribosomes.
    White adipose tissue is
    subdivided into
    incomplete lobules by a
    partition of connective
    tissue containing a rich
    vascular bed and nerve
    network. Fibroblasts,
    macrophages.
    Reticular fibers form a fine
    network that supports
    individual fat cells and
    binds them together.
    Adipose tissue is richly
    vascularized.
    Adipocytes undergo
    differentiation from
    embryonic mesenchymal
    cells.
    Such differentiation is first
    seen with the appearance
    of lipoblasts
    Early lipoblasts have the
    appearance of fibroblasts
    but are able to accumulate
    fat in their cytoplasm
    Lipid accumulations are
    isolated from one another
    at first but soon fuse to
    form the single larger
    droplet that is
    characteristic of unilocular
    adipose tissue cells.
    • Adipose tissue function as an
    endocrine organ- source of
    the hormone leptin which
    regulates the appetite and
    participates in regulating the
    amount of adipose tissue
    • It is well-established that
    increased visceral adipose
    tissue raises the risk of
    diabetes and cardiovascular
    disease whereas increased
    subcutaneous fat does not.
    Brown Adipose Tissue
    The color of brown adipose tissue or brown fat is due to:
     the numerous mitochondria
     large number of blood capillaries
    • Adipocytes of brown fat contain many small
    lipid inclusions and are therefore called
    multilocular
    • Function is heat production
    • In comparison with white adipose tissue, which
    is present throughout the body, brown adipose
    tissue has a much more limited distribution
    • Cells of brown adipose tissue cells are
    polygonal and generally smaller than cells of
    white adipose tissue but their cytoplasm
    contains a great number of lipid droplets of
    various sizes
    • These adipocytes have spherical and central
    nuclei
    In neonates (newborn infants),
    brown fat makes up about 5%
    of the body mass
    Is located on the back, along
    the upper half of the spine and
    toward the shoulders
    Is of great importance to
    avoid lethal cold (hypothermia
    is a major death risk for
    premature neonates)
    Brown adipose tissue resembles
    an endocrine gland in that its
    cells assume an almost
    epithelial arrangement closely
    associated with blood
    capillaries.
    The tissue is subdivided by
    partitions of connective tissue
    into lobules that are better
    delineated than the lobules of
    white adipose tissue
    Brown adipose tissue develops
    from embryonic mesenchyme
    The number of brown adipocytes
    increases again during cold
    adaptation, usually appearing
    as clusters of multilocular
    cells in white adipose tissue.
    Thank You

    You might also like