Bronchiectasis
Bronchiectasis
Bronchiectasis
Dr Ramish Saleem, PT
DPT(SMC)
MS-OMPT(RIU)
BRONCHIECTASIS
Definition:
• Abnormal and permanent dilation of bronchi.
• Focal or diffuse distribution.
• It is a disorder that typically affects older individuals.
• approximately 2/3 of patients are women.
• It is usually acquired but may result from an underlying
genetic or congenital defect of airway defences.
• Clinical consequences –chronic and recurrent
infection and Pooling of secretions in dilated airways.
PATTERNS OF BRONCHIECTASIS
Three different patterns of bronchiectasis have been
described
Cylindrical bronchiectasis: the involved bronchi appear
uniformly dilated.
Varicose bronchiectasis: the affected bronchi have an
irregular or beaded pattern of dilatation resembling
varicose veins.
Saccular (cystic) bronchiectasis: the bronchi have a
ballooned appearance at the periphery, ending in blind
sacs.
BRONCHIECTASIS
AETIOLOGY : IMPAIRED HOST
DEFENCE
• Local causes: Endobronchial obstruction
• Generalised impairment:
– 1. Immunoglobulin deficiency
– 2. Primary ciliary disorders
– 3. Cystic fibrosis
AETIOLOGY : NON-INFECTIOUS
• Toxins or toxic substances ; gastric contents
• Immune responses,
• Inflammatory diseases: ulcerative colitis,
rheumatoid arthritis, Sjögren syndrome
(chronic autoimmune disease in which the
body's white blood cells destroy the exocrine glands,
specifically the salivary and lacrimal glands, that
produce saliva and tears.)
• -1-Antitrypsin deficiency
Clinical features of bronchiectasis
Due to accumulation of pus in dilated
bronchi
• Chronic productive cough usually worse in mornings and
often brought on by changes of posture.
• Sputum often copious and persistently purulent in
advanced disease.
• Halitosis is a common accompanying feature
• SOB
Due to inflammatory changes in lung and pleura
surrounding dilated bronchi
• General health
When disease is extensive and sputum persistently
purulent a decline in general health occurs with weight
loss, anorexia, low-grade fever, and failure to thrive in
children. In these patients digital clubbing is common.
Physical signs
• may be unilateral or bilateral.
• If the bronchiectatic airways do not contain secretions and there is
no associated lobar collapse, there are no abnormal physical signs.
• When there are large amounts of sputum in the bronchiectatic
spaces numerous coarse crackles may be heard over the affected
areas.
• When collapse is present the character of the physical signs depends
on whether or not the proximal bronchus supplying the collapsed lobe
is patent (breath sounds are diminished if the airway is obstructed).
• Advanced disease may lead to scarring with associated overlying
bronchial breathing.
Bronchiectasis
• If wide spread
– Dyspnea
• Clubbing of the
fingers
• h pulmonary
blood pressure
Cor pulmonale
When to suspect
bronchiectasis?
• Chronic cough, sputum
• Hemoptysis
• Coarse rales
• Persistent respiratory
symptoms
• Recurrent pneumonia
• Progressive obstructive lung
disease
• Clubbing
Investigations
• Bacteriological and mycological examination of sputum
• In addition to common respiratory pathogens, sputum culture may
reveal Pseudomonas aeruginosa, fungi such as Aspergillus and
various Mycobacteria.
• Frequent cultures are necessary to ensure appropriate treatment of
resistant organisms.