4 - Hemorrhage and Blood Transfusion

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Hemorrhage and blood transfusion

Hemorrhage= blood out side the circulation(exravasated)


Types of hemorrhage:
1-according to vessel rupture -arterial - venous -
capillary
2- according to time of occurrence -primary (direct) -
reactionary with in 24 hours - secondary 7-14 days
3- according to visibility of injury - external (revealed) -
internal (concealed
Types of hemorrhage
Revealed hemorrhage
Concealed hemorrhage
Measurement of blood concentration
 Assessment must be related to preexisting blood volume that derived
from body weight
 Infant=80-85 ml\kg
 Adult=65-75ml\kg
 methods to determine blood concentration
 1- blood clot size of clenched fist = 500ml
 1-swellings in closed fractures tibia #=500-1500ml femoral #
= 1000-2000ml
 3- swab weighing 1gm=1ml of blood
 4- hemoglobin level normal 12-16 gm \dl no immediate changes
Treatment of hemorrhage

 A- stop hemorrhage by
 1-pressure and packing first aid measure
 2-position and rest ( trendelenburg position)
 3- operative technic use artery forceps or ligatures
 4- short wave diathermy
 5- topical application of hemostatic material as gelatin
surgyseal
 B- replace the blood loss by giving IV fluid or blood
Blood transfusion
 indications of transfusion
 1-blood loss due to trauma or pathological lesion
 2-major operative surgery
 3-sever burn decrease proteins and fluid , hemolysis
 4- post operative anemia
 5-preoperative chronic anemia
 6-to arrest hemorrhage in hemophilia and thrombocytopenia
Preparation of blood for transfusion

 1- compatible blood
 2-history of donor for HIV&HBV
 3-sterile plastic bag collection
 4-bag should contain anticoagulant
solution (CPD)
blood storage: cooled in 4 c,CPD shelf life
3wks,RBC reduced with in 24-72 h,WBC
destroyed with in 24 h, platelets survive 72h,
clotting factors are labile and fall quickly
Blood fractions

 1-packed cells in chronic anemia


 2-platelet rich plasma treat thrombocytopenia
 3-platelet concentrate
 4- plasma which can give albumin 4.5% for
sever burns
 ,FFP,CPPT,fibrinogen
Plasma and packed cells
Blood grouping and cross mach

 2 major groups of antigens ABO and RH


present on the RBC surface
 Group A contain anti B antibody
 Group B contain atiA antibody
 Group AB contain no ABO antibody
 Group 0 contain anti A and anti B antibody
 RH antigen present in 85 % of population
incomptability

 Reaction due to presence of Abs in recipient serum against donar


cells result in agglutination- hemolysis- renal tubular necrosis and RF
 Can be prevented by 1-ABO &RH grouping and cross maching
 Giving blood
 1-Prepare the site
 2-check donor blood computability
 3- insert canula
 4- give detailed written instructions
 5-warm blood to prevent cardiac arrest
complications
 1-congestive heart failure due to rabid infusion
 2-transfusion reactions as incomptability , simple
pyrexial reaction , allergic reaction , sensitization to
leukocyte and platelets. Immunological sensitization
 3- infections as HBV, HIV
 4- thrombophlebitis
 5-air embolism
 6-coagulopathy and DIC

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