MCQ Mood Disorder

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MCQs on

Mood Disorders

Dr Sayuri Perera
1. Depressive cognitions include

A. Delusions of reference

B. Guilt

C. Suicidal plans

D. Worthlessness

E. Pessimism
A. Delusions of reference - F

B. Guilt -T

C. Suicidal plans-F

D. Worthlessness-T

E. Pessimism -T
Depressive cognitions

• These are negative thoughts

• NOT delusions

• 3 groups
• Worthlessness

• Think that he is failing in everything

• Thinks that other people see him as a failure

• No longer feels confident


• Pessimism

• expects the worst

• foresees failures at work

• ruin of finances

• misfortune for family

• deterioration of health
• Guilt

• Unreasonable self blame about minor matters trivial act


of dishonesty or letting someone down

• Usually these have not been in the patients thoughts for


years , but when he becomes depressed they come
flooding back
2. Somatic symptoms of depression

A. Loss of weight

B. Constipation

C. Diurnal variation of mood

D. Amenorrhoea

E. Loss of appetite
A. Loss of weight - T

B. Constipation - T

C. Diurnal variation of mood-T

D. Amenorrhoea- T

E. Loss of appetite- T
Somatic symptoms of depression
• Also called Biological/Melancholic/Somatic/Vegetative

• Sleep disturbances

• Diurnal variation of mood

• LOA

• LOW

• Constipations

• Loss of libido

• Amenorrhoea

• These symptoms are frequent but not invariable in moderate and severe
depression
3. Delusions in depression include

A. Nihilistic delusions

B. Delusions of guilt

C. Hypochondriacal delusions

D. Delusions of impoverishment

E. Persecutory delusions
A. Nihilistic delusions-T

B. Delusions of guilt-T

C. Hypochondriacal delusions-T

D. Delusions of impoverishment-T

E. Persecutory delusions -T
• Delusions in depressive are concerned with the same ‘themes’
as mild, moderate depression

• But the thinking has progressed to a delusional level

• They are mood congruent

• Mood-congruent psychotic features means that the content of


the hallucinations and delusions is consistent with typical
depressive themes

• Themes are worthlessness, guilt, ill health, poverty


4. Genetics and mood disorders

A. Risk of mood disorders is increased in first and second


degree relatives

B. The risk is greater in relatives with bipolar patients

C. Relatives of bipolar patients have a higher risk of depression

D. Relatives of unipolar depression patients have a higher risk of


bipolar

E. Follows Mendelian inheritance


A. Risk of mood disorders is increased in first and second
degree relatives -F

B. The risk is greater in relatives with bipolar patients-T

C. Relatives of bipolar patients have a higher risk of depression


-T

D. Relatives of unipolar depression patients have a higher risk of


bipolar -F

E. Follows Mendelian inheritance -F


• Risk is greater in first degree

• Both bipolar and unipolar

• Risk is x 2 in relatives of bipolar patients

• Bipolar patients relatives-greater risk of unipolar depression,


schizoaffective disorder and bipolar depression

• Unipolar patients relatives-do not have a increased risk of


bipolar disorder or schizoaffective disorder
5. Life events and depression

A. There is an excess of life events in the months before the


onset of depression

B. Loss events are associated with anxiety

C. Threat events are associated with depression

D. Genetic factors shape the way that a person perceives life


events

E. Depressive episodes can occur in the absence of life events


A. There is an excess of life events in the months before
the onset of depression -T

B. Loss events are associated with anxiety-F

C. Threat events are associated with depression -F

D. Genetic factors shape the way that a person perceives


life events -T

E. Depressive episodes can occur in the absence of life


events-T
• x 6 increase of adverse life events in the months before
the onset of depressive disorder

• Loss events-depression

• Threat events- anxiety

• Genetic factors ( through personality) are important in


how a person perceives the life event

• Importance of life events decreases as the number of


episodes increases
• SBAs
1. A 24 year old patient presents a 3 week history of insomnia.
On interview you diagnose an episode of moderate depression
What is the best combination of medication

A. Fluoxetine 40mg nocte

B. Fluoxetine 20mg mane with Clonzepam 0.5mg nocte

C. Venlafaxine 75mg mane

D. Amitriptyline 25mg nocte

E. Sertraline 200mg mane with Clonazepam 0.5 mg nocte


• 1st line SSRIs - Fluoxetine and Sertraline

• Know the dosing ( dose and time )

• Lower doses first

• SSRIs are generally given in the morning

• Wont help insomnia, therefore give with a low dose of


benzodiazepine

• Venlafaxine is 2nd line

• TCAs are generally not encouraged due to side effects


2.A 45 year old male presents with severe depression and
an attempt of hanging
What is the next best step in managing this patient

A. Assess the current suicide risk

B. Start him on Fluoxetine 20mg mane

C. Prepare him for ECT

D. Assess the reasons for depression

E. Speak to his family


• All the steps are important

• The first step in management is to perform a risk assessment

• Suicide, Self neglect are most important

• Homicide

• Next is treatment

• Medication/Psychological therapy etc

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