Appetite Changes and Drugs 3
Appetite Changes and Drugs 3
Appetite Changes and Drugs 3
And Drugs
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Appetite
• Appetite is the desire to eat food, sometimes due to hunger.
• Appetite serves to regulate adequate energy intake to maintain metabolic needs.
• Appetitive behavior are the only processes that involve energy intake, whereas all
other behaviors affect the release of energy.
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Factors Affecting Appetite
1. Climate
2. Social Factors
3. Sickness And Injury
4. Exercise/Physical Activity
5. Hormonal Levels
6. Medicinal Side-Effects
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Climate
• Shivering or just being cold in general can increase metabolic
rate as much as five fold, potentially providing a healthy and
sustainable alternative way to burn energy and, thus calories.
• Food provides calories and fat that the body burns to keep itself
warm and moving. To help ensure enough warmth is provided, food
processed faster
• When in a cold environment, emptying stomach quicker and
feeling hungry more often.
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Social Factors
Social Gatherings – Special Occasions
Fast food – Large portion sizes
Enhanced Flavors
New Products – Marketing and Advertisements
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Sickness And Injury
• Dyspepsia (indigestion), severe physical stress or trauma such as a broken bone,
surgery, a burn and a high fever, reduces appetite and slows the natural contractions
of the intestinal tract.
• Eating under such conditions can stretch bowel enough to tear it and even cause food
to back up in the gut, which is why intravenous feeding — that’s, getting nutrients
via fluids injected into a vein — is a method doctors and nutritionists prefer during
the healing process.
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Exercise/Physical Activity
• People who exercise regularly tend to have a healthy appetite. One may not feel
hungry immediately after exercising, because physical activity pulls stored energy
(i.e. glucose and fatty acids) out of body tissues and into the bloodstream, giving of
the feeling of hunger.
• Exercise, both physical and mental, also empties stomach more slowly and slows the
passage of food through the digestive tract, making one feel fuller longer.
Hormonal Changes
• Leptin is a hormone, made by fat cells, that decreases appetite. Levels of leptin are
lower in a thin person and higher in a fat person. But many obese people have built
up a resistance to the appetite-suppressing effects of leptin.
• Ghrelin is a hormone that increases appetite, and also plays a role in body weight.
Ghrelin is released primarily in the stomach and is thought to signal hunger to
the brain.
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Medicinal Side-Effects
• Some drugs used to treat common health conditions affect appetite. Such a side
effect is rarely mentioned by doctors when they prescribe a drug, perhaps because it
isn’t life-threatening and usually goes away once you stop taking the drug.
• The fact that a drug affects appetite is almost never a reason to avoid using it.
However, knowing that a relationship exists between the drug and desire for food can
be helpful.
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Appetite Increasing medicines
Drugs that increase appetite include certain:
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Appetite decreasing medicines.
Continue..
Drugs that decrease appetite include certain:
o Antibiotics
o Anti-cancer drugs
o Anti-seizure drugs
o Cholesterol-lowering drugs
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Appetite Dysregulation – Role In
Disease
• Eating Disorders
Anorexia
Malnutrition
Bulimia nervosa
Polyphagia
Obesity
Binge-eating disorder
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Thank You!
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