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    Polygenic Inheritance

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    Sandeep Kumar Raghuvanshi
    This document discusses polygenic inheritance, which is when multiple non-allelic genes contribute to a quantitative trait. Some key points: - Polygenic traits do not follow Mendelian ratios and can be influenced by the environment. Examples include human skin color and wheat kernel color. - Early researchers who discovered polygenic inheritance include J.B. Koleuter, Herman Nilsson-Elhe, and Charles B. and Gertrude C. Davenport. - Polygenic inheritance results in continuous variation and intermediate phenotypes in offspring, unlike single-gene Mendelian traits which show discontinuous variation.

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    Polygenic Inheritance

    Uploaded by

    Sandeep Kumar Raghuvanshi
    123 views13 pages
    This document discusses polygenic inheritance, which is when multiple non-allelic genes contribute to a quantitative trait. Some key points: - Polygenic traits do not follow Mendelian ratios and can be influenced by the environment. Examples include human skin color and wheat kernel color. - Early researchers who discovered polygenic inheritance include J.B. Koleuter, Herman Nilsson-Elhe, and Charles B. and Gertrude C. Davenport. - Polygenic inheritance results in continuous variation and intermediate phenotypes in offspring, unlike single-gene Mendelian traits which show discontinuous variation.

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    INHERITANCE PATTERN IS DICUSSED

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    This document discusses polygenic inheritance, which is when multiple non-allelic genes contribute to a quantitative trait. Some key points: - Polygenic traits do not follow Mendelian ratios and can be influenced by the environment. Examples include human skin color and wheat kernel color. - Early researchers who discovered polygenic inheritance include J.B. Koleuter, Herman Nilsson-Elhe, and Charles B. and Gertrude C. Davenport. - Polygenic inheritance results in continuous variation and intermediate phenotypes in offspring, unlike single-gene Mendelian traits which show discontinuous variation.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    123 views13 pages

    Polygenic Inheritance

    Uploaded by

    Sandeep Kumar Raghuvanshi
    This document discusses polygenic inheritance, which is when multiple non-allelic genes contribute to a quantitative trait. Some key points: - Polygenic traits do not follow Mendelian ratios and can be influenced by the environment. Examples include human skin color and wheat kernel color. - Early researchers who discovered polygenic inheritance include J.B. Koleuter, Herman Nilsson-Elhe, and Charles B. and Gertrude C. Davenport. - Polygenic inheritance results in continuous variation and intermediate phenotypes in offspring, unlike single-gene Mendelian traits which show discontinuous variation.

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    Dr.

    Sandeep Kumar Raghuvanshi


    Department of Zoology
    Bareilly College, Bareilly
    •Polygene is when a dominant allele controls only a unit or partial
    quantitative expression of a trait.
    •Several non-allelic genes affect same character.
    •Also called multiple gene or quantitative or cumulative inheritance
    as trait becomes more pronounced when dominant alleles are
    added. •Each gene contributes equally.
    •Environmental factors may also effect.
    •Does not follow Mendelian ratio.
    •Examples include skin color in human, kernel color on wheat,
    human height, cob length in maize, etc.
    Joseph Gottlieb Koleuter : Father of polygenic inheritance
    Herman Nilsson-Elhe and East : First to discover polygenic
    inheritance in kernel color in wheat
    Charles B. Davenport and Gertrude C. Devenport:
    Discovered that the inheritance of skin color in human occurs
    by p

    J.B Koleuter H Nilsson C.B Davenport


    =*=--• ------ A • • 1 __I ^

    in pigmentation in human
    Trait Distribution

    Proportion of population

    7T
    D*
    "O
    to’
    Though melanin production is regulated by 3 genes as above, for
    convenience, we consider only two pairs of genes.

    AABB aabb
    Parents Albino
    Negro

    Gametes AB ab

    FI generati»n Mullato
    Fi AB Ab aB ab
    Gametes
    AB AABB AABb AaBB AaBb
    Negro Dark Dark Mulatto
    Ab AABb AAbb AaBb Aabb
    Dark Mulatto Mulatto Fair
    aB AaBB AaBb aaBB aaBb
    Dark Mulatto Mulatto Fair
    ab AaBb Aabb aaBb aabb
    Mulatto Fair Fair Albino

    F2 generation phenotypic Ratio= 1: 4: 6: 4: 1


    Gene 1 d'd1 d1D1 d'D' D'D1 D’d1 D1d» D'D1

    Gene 2 d2d2 d 2 d2 d2D2 D2d2 D2d2 D2D2 D2D2

    Gene 3 d3d3 d 3 d3 d3d3 d3d3 D3D3 D3D3 D3D3

    Total 0 1 2 3 4 5 6
    number of
    dark-skin
    genes

    Medium Very
    dark

    # of light
    5
    “d" alleles
    U of dark
    U
    D’ alleles 1
    Kernel Color in Wheat
    aa bb cc x AA BB CC
    (pure white line) (pure red line)

    l
    Aa Bb Cc (medium red)

    Self-fertilization

    AABbcc
    AAbbcc AaBbcc AAbbCc AABBcc AaBBcc AABbCc
    aaBBcc Aabbcc AabbCC AAbbCC aaBBCc AaBbCC
    AabbCc aaBbcc AABBCc aaBbCC aaBBCC AaBBCC
    aabbCC aabbCc AaBbCc AaBBCc AABbCC AABBCC
    aaBbCc
    aabbcc
    0 1 2 3 4 5 6
    Number of red pigment alleles (A, B or C) in genotype
    REO
    Par ents
    AABB WHITE
    aabb
    1
    Gametes
    F* Generation
    ► AB i
    MEOIUM ab
    AaBb
    Gametes

    AABB AABb AaBB AaBb


    RED OARK DARK MEOIUM

    AABb AAbb AaBb Aabt


    DARK MEOIUM MEDI UM LIGHT

    AaBB AaBb aaBB aaBb


    OARK MEOIUM MEOIUM LIGHT

    AaBt> Aabb aaBb aabb


    MEOIUM LIG HT LIGHT WHITE

    F2 generation phenotypic Ratio=1:4:6:4:1


    Human Eye Color
    Mother

    AB Ab aB ab

    AB • • • 9
    • #
    AABB AABb AaBB AaBb

    #
    Father

    Ab

    AaBb

    m # •
    AABb A Abb AaBb Aabb

    aB •
    # # #
    AaBB AaBb aaBB aaBb

    ab
    #

    AaBb Aabb aaBb aabb


    onogenic v/s Polygenic Inheritance
    Monogenic Inheritance Polygenic Inheritance

    Discontinuous variation Continuous variation


    Single allelic gene Many non-allelic genes
    Qualitative inheritance Quantitative inheritance
    F1 individual resembles F1 individual are intermediate
    dominant parent between the parents
    Phenotype not influenced by Phenotype influenced by
    environment environment
    No intermediates Numerous intermediates
    Eg: All seven characters studied Eg: Skin color in human, Wheat
    by Mendel kernel color, etc.
    YOU!

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