Staphylococcus
Staphylococcus
Staphylococcus
1
Staphylococci
strains
5
CARRIAGE
• Anterior nares -35%
• Perineum -20%
• Axillae - 5-10%
6
TOXINS PRODUCED BY S AUREUS
• Panton-Valentine leukocidin
Systemic treatment
• Penicillin is the drug of choice
• S. aureus strains resistant to penicillin G. can be treated with β-
lactamase–resistant penicillins (e.g., nafcillin or cloxacillin
• MRSA: The drug of choice for these staphylococci is
vancomycin, Linezolid, Daptomycin is also useful
MRSA infections
• Vancomycin
• Linezolid
• Quinipristine/dalfopristin
• Daptomycin
7
Supression of carriage
• Indications: where Staphylococcal dispersal is a