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    Classification of Anemia

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    muliamayangsari

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    Classification of Anemia

    Uploaded by

    muliamayangsari
    11 views8 pages

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    Copyright:

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    Download as ppt, pdf, or txt
    11 views8 pages

    Classification of Anemia

    Uploaded by

    muliamayangsari

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    of 8

    Classification of anemia

    • Functional classification:
    • Hypoproliferative destruction (infective
    hematopoiesis).
    • Clinical classification:
    • Causes of anemia (blood loss, IDA, hemolysis).
    • Quantitative classification:
    • Hematocrit
    • Hemoglobin
    • Blood cell indices (MCV, MCH, MCHC).
    • Reticulocytes count.
    Red cell indices
    MCV (mean corpuscular volume)
     The average volume of RBC
    Hct
    =  10 (fl)
    RBC count (m/µL)
    e.g. Hct= 40%
    RBC=5.0 (m /µL)
    MCV= 40/5.0  10 = 80 fl
    NR= 80-96 fl
    MCH (mean corpuscular hemoglobin)
     The average content of Hb in average RBC.
     It is directly proportional to the amount of Hb
    and RBC size.

    Hb
    MCH =  10 (pg)
    RBC count (m/µL)

    e.g. Hb = 14 g/dl
    RBC = 4 (m/µL)

    MCH= 14/4  10
    = 35 pg

    NR= 27-32 pg
    MCHC (mean corpuscular hemoglobin
    concentration)
     Express the average concentration of
    hemoglobin per unit volume of RBC.
     It defined as the ratio of the weight of
    hemoglobin to volume of RBC.
    Hb (g/dl)
    MCHC=  100 (%)
    Hct (%)

    e.g. Hb = 14 g/dl
    Hct = 45 %

    MCHC 14/45  100 = 31%

    NR= 32-36%
    Symptoms of Anemia

    Normal or High Hemoglobin/Hematocrit

    Check other
    Causes of symptoms
    e.g. Cardiac Low
    Pulmonary RBC indices

    MCV < 80 MCV=80-96 MCV > 98


    MCHC < 32
    History of acute blood loss
    B12 and folate
    Serum iron and Total Auto immune Hemolytic anemia
    Iron binding capacity Anemia of chronic Diseases levels
    of Ferritin Anemia of infection

    Low Iron Normal High Iron Low B12 Low folate High or Normal

    IDA, chronic Hb BM exam PA, GI Folate MPD


    diseases, Renal electrophoresis For problems malnutrition Liver Disease
    diseases for Thala. Sideroblastic Severe GI problems
    anemia malnutrition. Liver disease
    Normal red cell morphology
    Hypochromic Hyperchromic

    Macrocytic Microcytic
    IDA
    Target cells Stomatocytes

    Poikiolocytosis Sickle cells Acanthocytes

    Spherocytes
    Ovalocyte Nucleated RBC

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