Croup: Dr. Shveta Sethi Narula A.P. Microbiology

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Croup

Dr. Shveta Sethi Narula


A.P. Microbiology
• Croup is a respiratory illness characterized by inspiratory
stridor, cough, and hoarseness.
• The term croup has been used to describe a variety of upper
respiratory conditions in children including :
o Laryngitis
o Laryngotracheitis
o Laryngotracheobronchitis
o Bacterial tracheitis
o or spasmodic croup
• Croup is usually caused by viruses. Bacterial infection may
occur secondarily.
o Para influenza virus type 1,2 & 3
o Respiratory syncytial virus (RSV) and adenoviruses
o Measles
o Influenza virus
o Rhinoviruses
Bacterial infection: Croup also may be caused by bacteria.
The most common secondary bacterial pathogens include
o Staphylococcus aureus
o Streptococcus pyogenes
o Streptococcus pneumoniae
EPIDOMIOLOGY

• Croup affects about 15% of children


o most commonly occurs in children 6 to 36 months of age.
o It is more common in boys, with a male: female ratio of
about 4:1
o Most cases occur in the fall or early winter
• The viral pathogen is inhaled and infects the cells of the
respiratory epithelium. Consequently leading to localized
inflammatory response including-
o Inflammation of the subglottic area
o Mucosal edema
o Increased mucous production
o Narrowing of the internal airway lumen
Clinical presentation

 Hoarse or barking cough


 Nasal drainage
 Sore throat
 Low grade fever
 Tachycardia, Tachypnea
 Inspiratory stridor
• Children with more severe cases have:
O Visible suprasternal, intercostal, subcostal retractions.
O Lethargy and agitation
o Hypoxemia and Respiratory arrest
DIAGNOSIS

o Laboratory studies add little to the diagnosis of croup if bacterial


infection is not suspected.
o Croup is typically diagnosed based on signs and symptoms.
o White blood cell counts may be elevated above 10,000 with a
predominance of polymorphonuclear cells.
o Chest radiographs may show subglottic narrowing (in 50% of
children with croup)
o While viral cultures, obtained via nasopharyngeal aspiration, can
be used to confirm the exact cause, these are usually restricted
to research setting as they may cause unnecessary agitation and
thus worsen the stress on the compromised airway.
TREATMENT

o Keep child calm


O Steam
O Antipyretics
O Encouragement of fluid intake
O Humidified air
O Single dose of oral dexamethasone (0.6 mg/kg)
Supportive care
o Humidified air or humidified oxygen
o Monitoring
o Fluids
o Intubation
O Dexamethasone is the most commonly used, with the dose
being 0.6 mg/kg (maximum 10 mg) by mouth or
intramuscularly.

o Nebulized epinephrine may have marked effect to decrease


inspiratory stridor and the work of breathing
Prognosis

• Viral croup is usually a self-limited disease.


• The prognosis for croup is excellent, and recovery is almost
always complete.
• Symptoms usually improve within three days, but may last for
up to seven days.
• Less than 5 percent of children with croup require hospital
admission.
COMPLICATIONS

• Hypoxemia (oxygen saturation <92 percent in room air) and


respiratory failure.
• Pulmonary edema
• Pneumothorax, and
• Pneumomediastinum
• Otitis media
• Secondary bacterial Infections
• Bacterial tracheitis
Thank You

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