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    Clear Cell Acanthoma of The Mammary Region: A Case: Laporan Kasus Divisi TBK

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    Julian Lee
    1) Clear cell acanthoma is a rare, benign skin tumor of unknown etiology that appears as a well-defined pink or reddish-brown plaque or nodule, usually on the lower legs of middle-aged or elderly individuals. 2) A 43-year-old male presented with a dome-shaped lesion in his right mammary region that had been growing over two years. Examination found a pink, shiny 9mm plaque. 3) Histopathological examination of an excisional biopsy showed dilated dermal blood vessels and proliferation of clear keratinocytes, characteristic of clear cell acanthoma. Follow-up found no recurrence.

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    Clear Cell Acanthoma of The Mammary Region: A Case: Laporan Kasus Divisi TBK

    Uploaded by

    Julian Lee
    15 views12 pages
    1) Clear cell acanthoma is a rare, benign skin tumor of unknown etiology that appears as a well-defined pink or reddish-brown plaque or nodule, usually on the lower legs of middle-aged or elderly individuals. 2) A 43-year-old male presented with a dome-shaped lesion in his right mammary region that had been growing over two years. Examination found a pink, shiny 9mm plaque. 3) Histopathological examination of an excisional biopsy showed dilated dermal blood vessels and proliferation of clear keratinocytes, characteristic of clear cell acanthoma. Follow-up found no recurrence.

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    1) Clear cell acanthoma is a rare, benign skin tumor of unknown etiology that appears as a well-defined pink or reddish-brown plaque or nodule, usually on the lower legs of middle-aged or elderly individuals. 2) A 43-year-old male presented with a dome-shaped lesion in his right mammary region that had been growing over two years. Examination found a pink, shiny 9mm plaque. 3) Histopathological examination of an excisional biopsy showed dilated dermal blood vessels and proliferation of clear keratinocytes, characteristic of clear cell acanthoma. Follow-up found no recurrence.

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    15 views12 pages

    Clear Cell Acanthoma of The Mammary Region: A Case: Laporan Kasus Divisi TBK

    Uploaded by

    Julian Lee
    1) Clear cell acanthoma is a rare, benign skin tumor of unknown etiology that appears as a well-defined pink or reddish-brown plaque or nodule, usually on the lower legs of middle-aged or elderly individuals. 2) A 43-year-old male presented with a dome-shaped lesion in his right mammary region that had been growing over two years. Examination found a pink, shiny 9mm plaque. 3) Histopathological examination of an excisional biopsy showed dilated dermal blood vessels and proliferation of clear keratinocytes, characteristic of clear cell acanthoma. Follow-up found no recurrence.

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    LAPORAN KASUS DIVISI TBK

    Clear Cell Acanthoma of the Mammary Region: A Case


    Report
    Oleh
    dr. Anita Indah Sari
    Pembimbing :
    DR.dr.Siswanto Wahab,Sp.KK(K),FINSDV,FAADV
    DR.dr.Khaeruddin Djawad,Sp.KK(K),FINSDV,FAADV
    Dr.Airin R.N.Mappewali,Sp.KK(K),FINSDV,FAADV
    Prof.DR.dr.Anis Irawan Anwar,Sp.KK(K),FINSDV,FAADV
    Dr.Idrianty Idrus,Sp.KK,M.Kes

    Dibawakan dalam rangka tugas PPDS 1


    Bagian Ilmu Kesehatan Kulit dan Kelamin
    Fakultas Kedokteran Universitas Hasanuddin
    Makassar
    1
    2021
    INTRODUCTION

    Clear cell acanthoma is an


    Clear cell acanthoma is a well-
    uncommon, benign skin tumor of
    defined, pink to reddish-brown
    unknown etiology. Generally, it
    plaque or nodule appearing on
    appears on the lower legs of
    the skin with an average size of 5-
    middle-aged to elderly individuals
    10 mm
    with no gender predilection

    Dermoscopy features are


    The lesion is single but could be characteristic with blood vessels
    multiple also lined up in strings of pearls
    pattern
    2
    with a chief complaint of a dome-
    43-year-old male from Malaysia, shaped lesion in his right
    residing in Dubai mammary region for two years
    with an interval increase in size in
    the last few weeks

    CASE
    REPORT
    The patient had nine mm-sized
    Came to the outpatient dome-shaped, lobulated, shiny
    dermatology clinic at Saudi- pink colored plaque in the right
    German hospital Dubai mammary region's skin on local
    dermatological examination
    3
    4
    Differential Diagnosis

    Dermatofibroma Psoriatic plaque


    Pyogenic granuloma Eccrine poroma
    Inflamed seborrheic keratosis Clear cell hidradenoma
    Actinic keratosis Melanoma
    Basal cell carcinoma Squamous cell carcinoma
    Squamous cell carcinoma
    Verruca vulgaris

    5
    Clinical Diagnosis and Dermoscopy

    Dermoscopy picture was classical with glomerular and


    punctiform vessels with “pearl necklace” or “string of pearls’

    Vessels are organized in a reticular array

    6
    7
    Excision Biopsy

    Excisional biopsy was done under local anesthesia with a 3 mm negative surgical margin

    The shape of the scar was crescentic with concavity towards the areola

    Excisional biopsy of the lesion with histopathological examination showed dilated


    blood vessels in the dermal papillae and proliferation of clear keratinocytes

    The clear appearance of keratinocytes is due to vacuoles with glycogen as their contents
    on H & E staining

    8
    9
    DISCUSSION

    Clear cell acanthoma of the male mammary region is an exceedingly rare finding

    Etiology is idiopathic

    Asymptomatic benign epidermal tumor, which develops slowly over multiple years and
    remains stable for years

    3-month follow-up, no distortion or recurrence was seen in the nipple

    10
    CONCLUSION

    Clear cell acanthoma can occur in the male mammary region


    without any predisposing inflammatory skin conditions

    Malignant counterpart is a known rare opposite pole of this


    benign

    Excision biopsy even though the dermoscopy findings are unique

    11
    THANK YOU

    12

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