This document presents a case study of a 64-year-old male who presented with a chronic cough lasting 9 months. His history, physical exam findings, lab and imaging results are described in detail. Differential diagnoses considered include pulmonary tuberculosis, post-nasal drip syndrome, gastroesophageal reflux, chronic obstructive pulmonary disease, and pulmonary malignancy. Further workup revealed obstructive pneumonia secondary to a probable malignant pulmonary mass. He was admitted and started on IV antibiotics and medications to control his cough and hypertension.
This document presents a case study of a 64-year-old male who presented with a chronic cough lasting 9 months. His history, physical exam findings, lab and imaging results are described in detail. Differential diagnoses considered include pulmonary tuberculosis, post-nasal drip syndrome, gastroesophageal reflux, chronic obstructive pulmonary disease, and pulmonary malignancy. Further workup revealed obstructive pneumonia secondary to a probable malignant pulmonary mass. He was admitted and started on IV antibiotics and medications to control his cough and hypertension.
This document presents a case study of a 64-year-old male who presented with a chronic cough lasting 9 months. His history, physical exam findings, lab and imaging results are described in detail. Differential diagnoses considered include pulmonary tuberculosis, post-nasal drip syndrome, gastroesophageal reflux, chronic obstructive pulmonary disease, and pulmonary malignancy. Further workup revealed obstructive pneumonia secondary to a probable malignant pulmonary mass. He was admitted and started on IV antibiotics and medications to control his cough and hypertension.
This document presents a case study of a 64-year-old male who presented with a chronic cough lasting 9 months. His history, physical exam findings, lab and imaging results are described in detail. Differential diagnoses considered include pulmonary tuberculosis, post-nasal drip syndrome, gastroesophageal reflux, chronic obstructive pulmonary disease, and pulmonary malignancy. Further workup revealed obstructive pneumonia secondary to a probable malignant pulmonary mass. He was admitted and started on IV antibiotics and medications to control his cough and hypertension.
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Approach To Cough
Mark Angelo Z. Ponferrado, MD
Pre-resident Objectives 1. To identify the causes of chronic cough in a 64 year old male
2. To define cough and discuss approach to cough and treatment
Sample Case • R.J. • 64 years old, Male • Married • Roman Catholic • Filipino • Born on June 22, 1956 • Known Hypertensive • Admitted last December 16, 2020 Chief Complaint • Cough of 9 months History of Present illness 9 Months Prior Persistence 3 Months Prior Persistence 1 Week Prior
(+) Productive Cough Still with the above signs
(Whitish sputum) Still with the above signs and symptoms now (-) Fever, (-) Hemoptysis, (-) and symptoms associated with Shortness DOB, (-) Chest Pain (-) Body of Breath and Difficulty of Weakness Chest X-ray was done = Breathing (+) Self-medicated with Cardiomegaly Guaifenesin (+) Co-amoxiclav and No consult done Salbumatol nebules History of Present illness 1 day Prior Persistence Admission
(+) Difficulty of breathing
and palpitations.
Followed up with his
private physician
Advised for Admission
Past Medical History • (+) Hypertension = 5 years maintained on 50mg and claimed good compliance to medications • (-) DM • (-) Asthma • (-) PTB • (-) Previous Surgeries • (-) Allergies Family History • (+) Hypertension – Both Sides • (+) Malignancy (Bukol sa baga) • (-) DM • (-) PTB Personal Social History • Former 18.5 Pack-year smoker, stopped due to the onset of symptoms • Occasional Alcoholic Beverage drinker • Denies illicit drug use • Former furniture shop worker Review of Systems • No fever • No abdominal pain • No chills • No constipation • No nausea • No diarrhea • No dysuria • No blurring of vision • No numbness • No loss of vision • No tremors • No diplopia • No neck pain • No sore throat • No back pain • No congestion • No rash • No chest pain • No swelling • No Weight Loss • No edema Physical Exam Vital Signs upon arrival BP: 130/80 mmHg HR: 75 bpm RR: 19 cpm TEMP: 36.7 C O2sat: 98% at room air Physical Exam Conscious, coherent, not in cardiopulmonary distress Anicteric sclerae, pink palpebral conjunctiva, no nasoaural discharge, no cervicolymphadenopathy, no carotid bruit, no JVP distension Symmetrical chest expansion, no retractions, no lagging, Decreased breath sounds, Right lower lobe Increased tactile and vocal fremitus Adynamic precordium, normal rate, regular rhythm, no murmur, PMI not displaced Flat, soft, non tender, normoactive bowel sounds Grossly normal extremities, no cyanosis, no edema, full equal pulses, CRT < 2 secs Neuro Exam Mental status: alert, cooperative, no slurring of speech, oriented to person, place and time GCS 15 (E4V5M6) CN I: not assessed CN II: normal visual acuity, optic discs not assessed CN II, III: 2-3 mm pupil equally reactive to light, + direct/consensual reflex, no ptosis CN III, IV, VI: intact extra ocular movements, no nystagmus CN V: can clench teeth, + bicorneal reflex CN VII: able to raise both eyebrows, no facial asymmetry CN VIII: intact gross hearing CN IX, X: good gag reflex CN XI: able to shrug shoulders, no atrophy or fasciculations in trapezius muscle CN XII: tongue midline, no atrophy or fasciculations Salient Features • 64 Y/O Male • Known hypertensive • Presents with chronic cough of 9 months • (-) Fever, (-) Night Sweats, (-) Significant weight loss (-) Hemoptysis • (+) Decreased Breath Sounds with Increased Vocal and Tactile Fremitus on the right mid to base lung field Impression upon admission • CAP-MR; COVID Suspect CXR Chest CT With Contrast RESULT NORMAL VALUE WBC Count 11.99 5.00-10.00 RBC Count 4.53 4.00-6.00 Hemoglobin 123 110-150 Hematocrit 37.4 35.0-45.0 MCV 86.4 86.0-110.0 MCH 28.9 26.0-38.0 MCHC 335 316-354 Platelet count 332 150-400 Neutrophils 66.5 55.0-65.0 Lymphocytes 22.5 25.0-35.0 Monocytes 6.7 3.0-7.0 Eosinophils 1.8 0.4-8.0 Basophils 0.0 0.0-1.0 RESULT NORMAL VALUE BUN 2.57 2.14-7.14 CREA 73.39 44-80 AST 23.80 0-32.0 ALT 31.75 0-33.0 RBS 7.11 <7.80 SODIUM 134.3 135-145 POTASSIUM 4.71 3.4-5.3 Hba1c 4.8 % 4.0-6.0% URINALYSIS Color Straw Red blood cells 0-2 Transparency Clear White blood cells 2-4 Blood Negative Epithelial cells Few Urobilinogen Negative Bacteria Rare Ketones Normal Mucus Threads Few Protein Negative Nitrate Negative Glucose Negative Ph 0.5 Specific gravity 1.015 Leukocytes Negative Differential Diagnoses Acute Cough Subacute Cough Chronic Cough • Tracheobronchitis • Inflammatory • Respiratory Tract Infection • Infectious • Aspiration • Neoplastic • Inhalation of noxious • Cardiovascular chemicals Pulmonary Tuberculosis RULE IN RULE OUT • Chronic Cough • (-) Weight Loss • (+) DOB • (-) Night Sweats • (+) SOB • (-) Hemoptysis Post-nasal drip syndrome RULE IN RULE OUT • Chronic Cough • (-) Frequent Throat Clearing, • (-) Rhinorrhea • (-)Sneezing • (-) Inflamed/ edematous nasal mucosa Gastroesophageal Reflux RULE IN RULE OUT • Chronic Cough • (-) Weight Loss • (+) DOB • (-) Night Sweats • (+) SOB • (-) Hemoptysis Chronic Obstructive Pulmonary Disease RULE IN RULE OUT • Chronic Cough • (-) Weight Loss • Sputum Production • (-) Night Sweats • (+) 18.5 pack year • (-) Hemoptysis smoker Pulmonary Malignancy RULE IN RULE OUT • Chronic Cough • (-) Weight Loss • (+) 18.5 Pack-year • (-) Night Sweats smoker • (-) Hemoptysis Obstructive Pneumonia secondary to pulmonary mass probably malignant Hypertension St. II Controlled COVID 19 Negative Cough • Forceful expulsion of air from the lungs that helps to clear secretions, foreign bodies, and irritants from the airway
• Cough performs an essential protective function for human airways
and lungs. Cough Mechanism • Spontaneous cough is triggered by stimulation of sensory nerve endings that are thought to be primarily rapidly adapting receptors C fibers Assessment of Chronic Cough • The physical examination seeks clues suggesting the presence of cardiopulmonary disease, including findings such as wheezing or crackles on chest examination
• In virtually all instances, evaluation of chronic cough merits a chest
radiograph. Management • Admit to the ward • Therapeutics: • IVF: PNSS 1L x 80cc/hr 1. Piperacillin + Tazobactam • DIET: LSLF 4.5g TIV Q6 • Diagnostics: CBC with PC, 2. Levofloxacin 750 TIV OD PT PTT with INR, BUN, 3. Omeprazole 40mg/ tab 1 CREA, Na, K, UA, Sputum tab OD GS/CS, CXR PA, 12 L ECG, 4. Paracetamol 300mg TIV Chest CT with Contrast 5. Amlodipine 10mg/tab 1 tab OD Thank you so much for listening!