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    Poster of Septilin

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    Nishtha Kumar
    This study investigated the clinical and microbiological effects of the herbal drug Septilin as an adjunct to non-surgical periodontal treatment in chronic periodontitis patients. 68 subjects were divided into two groups, one receiving scaling and root planing plus placebo and the other receiving scaling and root planing plus Septilin. Clinical parameters like gingival index, plaque index, pocket probing depth, and clinical attachment level as well as counts of four periodontal pathogens were measured at baseline and 1, 3, and 6 months. The results showed greater reductions in microbial counts for the group receiving Septilin compared to the placebo group, indicating Septilin may provide benefits when used as an adjunct to non-s

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    Poster of Septilin

    Uploaded by

    Nishtha Kumar
    62 views1 page
    This study investigated the clinical and microbiological effects of the herbal drug Septilin as an adjunct to non-surgical periodontal treatment in chronic periodontitis patients. 68 subjects were divided into two groups, one receiving scaling and root planing plus placebo and the other receiving scaling and root planing plus Septilin. Clinical parameters like gingival index, plaque index, pocket probing depth, and clinical attachment level as well as counts of four periodontal pathogens were measured at baseline and 1, 3, and 6 months. The results showed greater reductions in microbial counts for the group receiving Septilin compared to the placebo group, indicating Septilin may provide benefits when used as an adjunct to non-s

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    This study investigated the clinical and microbiological effects of the herbal drug Septilin as an adjunct to non-surgical periodontal treatment in chronic periodontitis patients. 68 subjects were divided into two groups, one receiving scaling and root planing plus placebo and the other receiving scaling and root planing plus Septilin. Clinical parameters like gingival index, plaque index, pocket probing depth, and clinical attachment level as well as counts of four periodontal pathogens were measured at baseline and 1, 3, and 6 months. The results showed greater reductions in microbial counts for the group receiving Septilin compared to the placebo group, indicating Septilin may provide benefits when used as an adjunct to non-s

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    62 views1 page

    Poster of Septilin

    Uploaded by

    Nishtha Kumar
    This study investigated the clinical and microbiological effects of the herbal drug Septilin as an adjunct to non-surgical periodontal treatment in chronic periodontitis patients. 68 subjects were divided into two groups, one receiving scaling and root planing plus placebo and the other receiving scaling and root planing plus Septilin. Clinical parameters like gingival index, plaque index, pocket probing depth, and clinical attachment level as well as counts of four periodontal pathogens were measured at baseline and 1, 3, and 6 months. The results showed greater reductions in microbial counts for the group receiving Septilin compared to the placebo group, indicating Septilin may provide benefits when used as an adjunct to non-s

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    © All Rights Reserved
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    “SEPTILIN, AS AN ADJUNCT TO NON SURGICAL TREATMENT IN CHRONIC PERIODONTITIS SUBJECTS: A DOUBLE BLINDED PLACEBO CONTROLLED CLINICAL TRIAL”

    AIM-- To investigate the clinical and microbiological effects of Septilin a drug of Indian Ayurvedic
    septilin as an adjunct to the non surgical treatment in chronic Medicine
    periodontitis subjects.
    IMMUNOMODULATORY
    STUDY FLOW CHART
    ASSESSED FOR ELIGIBILITY (n=82) INCLUSION CRITERIA ANTI-INFLAMMATORY
    •Age 20-44 yrs. ANTI-INFECTIVE
    Excluded,
    Excluded, n=2
    n=2 •Atleast 20 natural teeth.
    Not
    Not meeting
    meeting criteria=7
    Refused
    Refused to
    criteria=7
    to participate=5
    participate=5 •No PDL therapy --last 6
    ANTI-EXUDATIVE
    months WOUND HEALING
    N=68
    (36 males and 32
    EXCLUSION CRITERIA
    ANTI-ALLERGIC
    females)
    females)
    Oral
    Oral hygiene
    hygiene •Known systemic diseases.
    instructions, SRP •Pregnant/ Lactating women.
    •Smokers. RESULTS
    •Under any medications. MICROBIAL COUNT (Aa,Pg,Td,Tf) by PCR
    Group
    Group 1,
    1, N
    N== 36 Group
    Group 22 ,, N
    N== 32
    •Aggressive Periodontitis
    (SRP
    (SRP +
    + Placebo)
    Placebo)
    36
    (SRP
    (SRP +SEPTILIN)
    +SEPTILIN)
    32
    5
    EVALUATION 4
    BASELINE
    Failed
    Failed to
    to follow-up
    follow-up
    N=6
    N=6
    Failed
    Failed to
    to follow-up
    follow-up
    N=2
    N=2 CLINICAL PARAMETERS GI, 3 1 MONTH
    PI, PPD & CAL. MICROBIAL 2 3 MONTHS
    COUNT (Aa,Pg,Td,Tf) by PCR
    Analysed
    Analysed
    N=30
    Analysed
    Analysed
    N=30
    1 6 MONTHS
    N=30 N=30
    0
    PLACEBO SEPTILIN
    CONCLUSION- Within the limitations of the study, patients with chronic periodontitis harbouring
    A. actinomycetemcomitans, P.gingivalis, T. forsythia & T.denticola in their subgingival biofilm may
    benefit from the systemic administration of SEPTILIN as an adjunct to SRP. However, further long
    term longitudinal trials considering other periodontopathic microorganisms are required to confirm
    the effectiveness of SEPTILIN in periodontitis.
    Reg. No. 1506

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