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    Diseases Related Proteins and Recent Developments Concerning Proteins

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    Jaymarie Zabate
    The document discusses proteins and recent developments related to diseases caused by protein misfolding. It explains that protein misfolding can occur through genetic mutations or environmental factors and disrupt cellular function. Diseases caused by the abnormal folding of specific proteins include Alzheimer's, Parkinson's, Huntington's, cystic fibrosis, and Gaucher's disease. Recent developments in protein engineering aim to increase protein stability, activity, and applicability through methods like rational design, directed evolution, and computational approaches.

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    Diseases Related Proteins and Recent Developments Concerning Proteins

    Uploaded by

    Jaymarie Zabate
    19 views11 pages
    The document discusses proteins and recent developments related to diseases caused by protein misfolding. It explains that protein misfolding can occur through genetic mutations or environmental factors and disrupt cellular function. Diseases caused by the abnormal folding of specific proteins include Alzheimer's, Parkinson's, Huntington's, cystic fibrosis, and Gaucher's disease. Recent developments in protein engineering aim to increase protein stability, activity, and applicability through methods like rational design, directed evolution, and computational approaches.

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    The document discusses proteins and recent developments related to diseases caused by protein misfolding. It explains that protein misfolding can occur through genetic mutations or environmental factors and disrupt cellular function. Diseases caused by the abnormal folding of specific proteins include Alzheimer's, Parkinson's, Huntington's, cystic fibrosis, and Gaucher's disease. Recent developments in protein engineering aim to increase protein stability, activity, and applicability through methods like rational design, directed evolution, and computational approaches.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    19 views11 pages

    Diseases Related Proteins and Recent Developments Concerning Proteins

    Uploaded by

    Jaymarie Zabate
    The document discusses proteins and recent developments related to diseases caused by protein misfolding. It explains that protein misfolding can occur through genetic mutations or environmental factors and disrupt cellular function. Diseases caused by the abnormal folding of specific proteins include Alzheimer's, Parkinson's, Huntington's, cystic fibrosis, and Gaucher's disease. Recent developments in protein engineering aim to increase protein stability, activity, and applicability through methods like rational design, directed evolution, and computational approaches.

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    You are on page 1of 11

    DISEASES RELATED

    PROTEINS AND RECENT


    DEVELOPMENTS
    CONCERNING PROTEINS
    PREPARED BY:
    BARLISO, LOVE FATE
    Proteins are one of the most
    important and resourceful
    biomolecules that find applications
    in health, industry, medicine,
    research, and biotechnology.
    PROTEIN MISFOLDING
    It is a common cellular event that can occur
    throughout the lifetime of a cell, caused by
    different events including genetic mutations,
    translational errors,
    abnormalprotein modifications, and incomplete
    complex formations
    WHAT CAUSES A PROTEIN TO FOLD?

    • Hydrophobic and hydrophilic interactions


    The cell is an aqueous (water-filled) environment.
    Some amino acids have polar (hydrophilic) side
    chains while others have non-polar (hydrophobic)
    side chains.
    THE PROTEOPATHIES

    In medicine, proteopathy refers to a
    class of diseases in which certain proteins
    become structurally abnormal, and
    thereby disrupt the function of cells,
    tissues and organs of the body.
    WHAT ARE THE DISEASES CAUSED BY
    PROTEIN?
    • Alzheimer’s Disease

    • Parkinson’s Disease
    • Huntington’s Disease

    • Creutzfeldt-Jakob disease
    • Cystic Fibrosis

    • Gaucher’s Disease
    SYMPTOMS

    • Fatty Liver
    • Skin, Hair and Nail Problems
    • Loss of Muscle Mass
    • Greater risk of bone fractures
    • Stunted growth in children
    • Increased Security of Infections
    RECENT DEVELOPMENTS
    • Protein Engineering Strategic Utilization Methods
    -Better stability
    -Increased Catalyic Activity
    -Wide range of Applicability of proteins
    • Current trends in protein engineering approaches
    -rational design
    -directed evolution
    -de novo design
    -computational approaches
    -encompasses the recent progresses made in this field over the last few years
    Thank you!

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