The document describes a 75-year-old male patient admitted to the hospital with hematemesis and malena due to Mallory-Weiss syndrome caused by a laceration at the gastroesophageal junction from large hiatus hernia and ulcers. Medical history includes Parkinson's disease, hypertension, diabetes. Treatment involved monitoring, IV medications to stop bleeding and prevent complications, and endoscopy showed hiatal hernia and Mallory-Weiss tear which require repair.
The document describes a 75-year-old male patient admitted to the hospital with hematemesis and malena due to Mallory-Weiss syndrome caused by a laceration at the gastroesophageal junction from large hiatus hernia and ulcers. Medical history includes Parkinson's disease, hypertension, diabetes. Treatment involved monitoring, IV medications to stop bleeding and prevent complications, and endoscopy showed hiatal hernia and Mallory-Weiss tear which require repair.
The document describes a 75-year-old male patient admitted to the hospital with hematemesis and malena due to Mallory-Weiss syndrome caused by a laceration at the gastroesophageal junction from large hiatus hernia and ulcers. Medical history includes Parkinson's disease, hypertension, diabetes. Treatment involved monitoring, IV medications to stop bleeding and prevent complications, and endoscopy showed hiatal hernia and Mallory-Weiss tear which require repair.
The document describes a 75-year-old male patient admitted to the hospital with hematemesis and malena due to Mallory-Weiss syndrome caused by a laceration at the gastroesophageal junction from large hiatus hernia and ulcers. Medical history includes Parkinson's disease, hypertension, diabetes. Treatment involved monitoring, IV medications to stop bleeding and prevent complications, and endoscopy showed hiatal hernia and Mallory-Weiss tear which require repair.
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SUBMITTED BY – GADDAM TEJASWINI
DOCTOR OF PHARMACY-4th YEAR
16Z91T0011 SUBMITTED TO- DR.B.HEPSHIBHA DEPT. OF CLINICAL PHARMACY Mallory–Weiss syndrome Mallory–Weiss syndrome or gastro- esophageal laceration syndrome refers to bleeding from a laceration in the mucosa at the junction of the stomach and esophagus. The syndrome presents with hematemesis. PATIENT DETAILS:- NAME – ABCD AGE – 75 Years GENDER - Male WEIGHT – 65 Kgs IP NO. – ASIP190000661 DOA – 23/09/2019 REASONS FOR ADMISSION : C/O – Hematemesis (3 to 4 episodes in last 24 hrs) , malena H/O – large hiatus hernia, 2 deep linear ulcers @ Z line , parkinsonism , hypertension, diabetics mellitus PMHx :
T.Gluconorm SR 500 mg – DM-type
II T.Met XL – trio 25mg – hypertension T.Minipress XL 5mg - hypertension T.Tegrital – 200 mg – trigeminal neuralgia T.Clopitab 75mg - antiplatelet Diet – mixed Allergies – not significant SHx – not significant Social Hx – smoker- 10 yrs General examination Patient conscious and mild disorientation Gait – Shuffling gait with tendency to fall forward and backward Temp – 98.6 F Pulse – 112 / min BP – 170 / 11o mmHg RESP – 22 SP02 – 100% CVS – S1 Advice Complete blood picture Troponin T Kidney function test Blood glucose 2 D Echo Doppler Endoscopy USG ECG COMPLETE BLOOD PICTURE COMPONENTS REFERENCE 23/09 24/09 25/09 26/09
HEMOGLOBIN 13-17 g/dl 8.8 7.5 7.8 9.3
RBC 4.5 – 5.5 million /mm3 2.7 2.3 2.5 2.9
PCV 40- 50% 25 21 22 26
WBC 4000 – 10000 cells/ 16400 13400 13400 12900
mm3 NEUTROPHILS 40-80% 85 85 84 84
LYMPOCYTES 20-40% 10 10 10 10
MCHC 32-35 g/dl 30 30 31 35
COMPONENTS REFERENCE 23/09 24/09 25/09
Blood urea 13 – 43 mg/dl 126 58 26
Creatinine 0.7 – 1.3 mg/dl 1.1 0.7 0.7
Na+ 136 – 145 mEq/L 135 139 134
k+ 3.5 – 5.1 mEq/L 4.9 3.5 3.7
cl- 98-107mEq/L 100 103 98
Total proteins 6-8g/dl 5.4
Albumin 3.5 – 5.2 g/dl 3.3
Globulin 2.3 – 3.5g/dl 2.1
COMPONENT REFERENCE VALUE TROPONIN((HIGH 11.2mg/ml 0-14 SENSITIVE) COMPONENT REFERENCE VALUE HbA1C >6.5 diabetic 5.4% Fasting blood 80-120mg/dl 163 glucose LIPID PROFILE COMPONENT REFERENCE VALUE
TOTAL <200mg/dl 120mg/dl
CHOLESTEROL HDL <40 POOR 27mg/dl DIRECT LDL <100 – for diabetes 69mg/dl and heart VLDL 2-30 mg/dl 24mg/dl CHOLESTEROL TRIGLYCERIDES Less than 15 normal 118mg/dl USG – Hepatomegaly with fatty infiltration, cholelithiasis, thick walled UB with BPM 2-D ECHO DOPPLER - Gr – 1 Lv diastolic dysfunction ENDOSCOPY – Large hiatus hernia, Mallory Weiss tear TREATMENT DAY 1 DRUG DOSE ROUTE FREQENCY
INJ. MONOCET Igm Iv 1-0-1
INJ.NEKSIUM 80mg Iv 0-0-1
INJ.XAMIC 500mg iv 1-1-1
INJ.VIT K 10mg iv 0-1-0
INJ.ZOFER 4g iv sos
INJ.LASIX 20mg iv start
TAB.PROLOMET-XL 25mg p/o 0-1-0
TAB.SYNDOPA PLUS 100mg p/o 1-0-1
INJ.TERLYZ WITH 1mg iv stat
100ml 20 pcv reserved. DAY- 2- ADV- to stop xamic and to add T.Ropinirole – 0.5mg p/o 0-0-1 to add hinex st with water p/o 3scoops -1-1-1 and add tab.urimax –d p/o 0-1-0 • DAY-3 :- Same • DAY 4 :- adv to add Duphalac 30ml 0-0-1 GOALS OF THE TREATMENT: • To relieve signs and symptoms (malena, Hematemesis ) • To prevent further complications • Maintain overall quality of life • Reduce tremor • Reverse slowed movements. • Improve posture, gait, balance, speech, and writing skills. • Improve mobility and function. • minimizing medication side effects • to remove the hernia sac and close the abnormally wide esophageal hiatus MONITORING PARAMETERS Blood pressure Diabetes mellitus Adr’s Complete blood picture movement PATIENT COUNSELLING:- About the disease: Signs and symptoms Prognosis Complications About the medication Medication adherence(dose, frequency) Adr’s About the life style modification Quit smoking