The patient presented with loss of appetite, generalized weakness, and a urine culture positive for E. coli and Acinetobacter baumanii, consistent with urosepsis. Symptoms of loose stool, abdominal discomfort and pain, hypotension, and leukocytosis align with a diagnosis of gastroenteritis or lactic acidosis from metformin use and CKD. Elevated BUN and creatinine with acidosis could indicate nephrotoxin ingestion. Signs of fever, leukocytosis, hyperglycemia, hypotension, tachycardia, tachypnea, thrombocytopenia and cold extremities support a diagnosis of septic shock. Hypotension, tachycardia, and t
The patient presented with loss of appetite, generalized weakness, and a urine culture positive for E. coli and Acinetobacter baumanii, consistent with urosepsis. Symptoms of loose stool, abdominal discomfort and pain, hypotension, and leukocytosis align with a diagnosis of gastroenteritis or lactic acidosis from metformin use and CKD. Elevated BUN and creatinine with acidosis could indicate nephrotoxin ingestion. Signs of fever, leukocytosis, hyperglycemia, hypotension, tachycardia, tachypnea, thrombocytopenia and cold extremities support a diagnosis of septic shock. Hypotension, tachycardia, and t
The patient presented with loss of appetite, generalized weakness, and a urine culture positive for E. coli and Acinetobacter baumanii, consistent with urosepsis. Symptoms of loose stool, abdominal discomfort and pain, hypotension, and leukocytosis align with a diagnosis of gastroenteritis or lactic acidosis from metformin use and CKD. Elevated BUN and creatinine with acidosis could indicate nephrotoxin ingestion. Signs of fever, leukocytosis, hyperglycemia, hypotension, tachycardia, tachypnea, thrombocytopenia and cold extremities support a diagnosis of septic shock. Hypotension, tachycardia, and t
The patient presented with loss of appetite, generalized weakness, and a urine culture positive for E. coli and Acinetobacter baumanii, consistent with urosepsis. Symptoms of loose stool, abdominal discomfort and pain, hypotension, and leukocytosis align with a diagnosis of gastroenteritis or lactic acidosis from metformin use and CKD. Elevated BUN and creatinine with acidosis could indicate nephrotoxin ingestion. Signs of fever, leukocytosis, hyperglycemia, hypotension, tachycardia, tachypnea, thrombocytopenia and cold extremities support a diagnosis of septic shock. Hypotension, tachycardia, and t
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Working Impression: Urosepsis
RULE IN RULE OUT
Loss of appetite (-) tenderness on the suprapubic Generalized body weakness area Urine culture: Colonies of (-) flank pain/costovertebral angle Escherichia coli and Acinetobacter tenderness baumanii (-) urinary symptoms Leukocytosis, neutrophilia, lymphopenia D/dx: Gastroenteritis RULE IN RULE OUT Loose watery stool (3- Stool culture: No enteric 4x/day) pathogen Vague abdominal (-) nausea, vomiting discomfort (at admission) Nontender abdomen Colicky abdominal pain (Day 7) Hypotension Leukocytosis, neutrophilia, lymphopenia D/dx: LACTIC ACIDOSIS RULE IN RULE OUT Metformin use No changes in sensorium CKD Loose watery stool (3- 4x/day) Hypotension Shortness of breath Metabolic acidosis Generalized body weakness D/dx: Nephrotoxin Ingestion RULE IN RULE OUT
Acute presentation Persistently elevated WBC
Elevated BUN, creatinine Acidosis Working Impression: Septic Shock RULE IN Febrile Leukocytosis Hyperglycemia Hypotension Tachycardia Tachypnea Thrombocytopenia Cold clammy extremities Urine Culture of Acinetobacer baumanii and E. coli D/Dx: Cardiogenic Shock RULE IN RULE OUT Hypotension Unremarkable Tachycardia Cardiovascular PE and Tachypnea ECG findings D/Dx: Hypovolemic Shock RULE IN RULE OUT Hypotension No source of volume Tachycardia loss (cessation of GI Tachypnea bleeding and diarrhea) Cool, clammy extremities