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    Gonorrhea: Fakhri Mubarok 151021033

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    This document discusses gonorrhea, caused by the bacterium Neisseria gonorrhoeae. It describes the etiology, morphology, epidemiology, clinical symptoms, diagnosis and differences between how it presents in men and women. Gonorrhea commonly causes urethritis in men and cervicitis or pelvic inflammatory disease in women. Diagnosis involves gram staining, culturing, biochemical tests and serological tests to detect antibodies against N. gonorrhoeae.

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    Gonorrhea: Fakhri Mubarok 151021033

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    Fakhri
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    This document discusses gonorrhea, caused by the bacterium Neisseria gonorrhoeae. It describes the etiology, morphology, epidemiology, clinical symptoms, diagnosis and differences between how it presents in men and women. Gonorrhea commonly causes urethritis in men and cervicitis or pelvic inflammatory disease in women. Diagnosis involves gram staining, culturing, biochemical tests and serological tests to detect antibodies against N. gonorrhoeae.

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    This document discusses gonorrhea, caused by the bacterium Neisseria gonorrhoeae. It describes the etiology, morphology, epidemiology, clinical symptoms, diagnosis and differences between how it presents in men and women. Gonorrhea commonly causes urethritis in men and cervicitis or pelvic inflammatory disease in women. Diagnosis involves gram staining, culturing, biochemical tests and serological tests to detect antibodies against N. gonorrhoeae.

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    Download as pptx, pdf, or txt
    24 views13 pages

    Gonorrhea: Fakhri Mubarok 151021033

    Uploaded by

    Fakhri
    This document discusses gonorrhea, caused by the bacterium Neisseria gonorrhoeae. It describes the etiology, morphology, epidemiology, clinical symptoms, diagnosis and differences between how it presents in men and women. Gonorrhea commonly causes urethritis in men and cervicitis or pelvic inflammatory disease in women. Diagnosis involves gram staining, culturing, biochemical tests and serological tests to detect antibodies against N. gonorrhoeae.

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    of 13

    GONORRHEA

    Fakhri Mubarok 151021033


    Semua penyakit infeksi yg disebabkan o/ Neisseria
    gonorrhea (genito-genital, oro-genital, ano-genital)
    ETIOLOGI

    Neisseria gonorrhoeae kuman


    kokus Gram (-), ukuran 0.6-1.5
    um; diplokokus
    Terlihat di luar & di dlm leukosit
    Tdk tahan lama di udara bebas
    Tdk motil; (-) spora
    Cepat mati dlm kead kering
    Tdk tahan suhu >39C & desinfektan

    Daerah yg paling mdh terinfeksi :


    daerah dgn mukosa epitel kuboid/lapis
    gepeng yg blm berkembang
    MORFOLOGI

    Membran sitoplasma
    Lapisan peptidoglikan
    Dinding sel
    Lap polisakarida
    Pili
    Protein
    Porin protein
    Opa
    RMP
    Lipooligosakarida
    Ig A1 protease
    EPIDEMIOLOGI
    Insidensi tinggi; tersebar di seluruh dunia scr
    endemik
    Di AS : 400.000-1 jt/th

    20-24 tahun 15-19 tahun


    Differences Between Men & Women
    with Gonorrhea
    IN MEN:
    Urethritis; Epididymitis
    Most infections among men are acute and symptomatic with purulent
    discharge & dysuria (painful urination) after 2-5 day incubation period
    The two bacterial agents primarily responsible for urethritis among men
    are N. gonorrhoeae and Chlamydia trachomatis

    IN WOMEN:
    Cervicitis; Vaginitis; Pelvic Inflammatory Disease (PID)
    Women often asymptomatic or have atypical indications.serious
    complication in case of untreated infection ranging from PID
    complications to infertility
    Pelvic Inflammatory Disease (PID) May also be asymptomatic, but
    difficult diagnosis accounts for many false negatives Can cause
    irreversible damage (scarring ) of fallopian tubes leading to infertility
    or ectopic pregnancy (egg trapped in fallopian tube and fetus begin to
    develop here)
    GEJALA KLINIS
    Uretritis
    >> uretritis anterior akuta
    Gx;
    Rasa gatal & panas di bag
    distal rethra sekitar OUE
    Disuria
    Polaksiuria
    Keluar duh mukopurulen dr
    OUE, kdg disertai darah &
    nyeri saat ereksi
    PF : OUE hiperemis, edema,
    ektropion
    Tysonitis
    Parauretritis
    Littritis
    Cowperitis
    Prostatitis
    Rasa tdk nyaman di daerah
    perineum & suprapubis
    Malaise-demam
    Disuria
    Hematuria
    Spasme otot urethra
    Retensi urin
    Vesikulitis
    Vas deferenitis/funikulitis
    Epididimitis
    Trigonitis
    Uretritis
    Gx : disuria, kdg poliuria
    PF : OUE merah,
    edematosa, & ditemukan
    sekret mukopurulen
    Parauretritis/skenitis Infeksi non genital
    Servisitis Proktitis
    Dpt asimptomatis nyeri pd Orofaringitis
    punggung bwh Konjungtivitis
    Bartholinitis Genitalia
    Salpingitis diseminata
    DIAGNOSIS
    Px penunjang
    Sediaan langsung
    Gonokok Gram (-) intraseluler &
    ekstraseluler
    Kultur
    Media transpor
    Media transpor media Stuart,
    media Transgrow
    Media pertumbuhan Mc Leods
    chocolate agar, media Thayer
    Martin, modified Thayer Martin
    agar
    Tes identifikasi presumtif &
    konfirmasi (definitif)
    Tes oksidase
    Tes fermentasi
    Tes beta laktamase
    Tes Thomson
    Uji serologis (70%)
    Px antibodi thd N. Gonorrhoeae spt
    Fiksasikomplemen
    Imunopresipitasi
    Imunofloresensi
    ELISA

    Deteksi asam nukleat

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