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    Rheumatoid Arthritis

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    Carmelita Christina
    Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease that primarily targets the synovial tissues. While the exact cause is unknown, it involves genetic and environmental factors that lead to an abnormal immune response. Symptoms include pain, stiffness, swelling and decreased range of motion in the joints of the hands, feet, wrists, knees and ankles. A diagnosis is made based on meeting at least four out of seven criteria including morning stiffness, joint involvement of three or more areas, hand joint arthritis, symmetric arthritis and laboratory tests. Treatment focuses on reducing inflammation and preventing further joint damage using medications like NSAIDs, steroids, and disease-modifying drugs.

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    Rheumatoid Arthritis

    Uploaded by

    Carmelita Christina
    374 views11 pages
    Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease that primarily targets the synovial tissues. While the exact cause is unknown, it involves genetic and environmental factors that lead to an abnormal immune response. Symptoms include pain, stiffness, swelling and decreased range of motion in the joints of the hands, feet, wrists, knees and ankles. A diagnosis is made based on meeting at least four out of seven criteria including morning stiffness, joint involvement of three or more areas, hand joint arthritis, symmetric arthritis and laboratory tests. Treatment focuses on reducing inflammation and preventing further joint damage using medications like NSAIDs, steroids, and disease-modifying drugs.

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    ppt RA inggris

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    Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease that primarily targets the synovial tissues. While the exact cause is unknown, it involves genetic and environmental factors that lead to an abnormal immune response. Symptoms include pain, stiffness, swelling and decreased range of motion in the joints of the hands, feet, wrists, knees and ankles. A diagnosis is made based on meeting at least four out of seven criteria including morning stiffness, joint involvement of three or more areas, hand joint arthritis, symmetric arthritis and laboratory tests. Treatment focuses on reducing inflammation and preventing further joint damage using medications like NSAIDs, steroids, and disease-modifying drugs.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    374 views11 pages

    Rheumatoid Arthritis

    Uploaded by

    Carmelita Christina
    Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease that primarily targets the synovial tissues. While the exact cause is unknown, it involves genetic and environmental factors that lead to an abnormal immune response. Symptoms include pain, stiffness, swelling and decreased range of motion in the joints of the hands, feet, wrists, knees and ankles. A diagnosis is made based on meeting at least four out of seven criteria including morning stiffness, joint involvement of three or more areas, hand joint arthritis, symmetric arthritis and laboratory tests. Treatment focuses on reducing inflammation and preventing further joint damage using medications like NSAIDs, steroids, and disease-modifying drugs.

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    RHEUMATOID

    ARTHRITIS
    DEFINITION

    Rheumatoid
    arthritis,achronic,
    systemic,
    inflammatory
    autoimmune
    disease,hasasits
    primarytargetthe
    synovialtissues.
    ETIOLOGY
    Thedefinitcauseofrheumatoidarthritisis
    unknown,becauseitisverycomplicatedandthe
    scientistisstilldoingthesurveilance,butthe
    mechanisminpathologycanconcludeseveralcauses
    ofRA

    immune
    regulatoryfactors
    Gene

    Smoking
    andotherformsof
    environment
    bronchialstress
    Sexhormone Androgen

    Infection Abnormal
    imunerespon
    EPIDEMIOLOGY
    InIndonesia,the
    prevalenceisunder0,4%.
    Incentraljavathe
    Thehigh prevalenceisabout0.2%,
    prevalencefound inMalang0,5%.
    inPimaIndian InRSCipto
    MangunkusumoJakarta,
    andChippewa
    insidensofRAfrom
    Indian,about januaryuntilJune2007is
    5,3%and6,8% about203case.

    Thecaseis
    usuallyfoundin
    woman
    PATHOLOGY

    Jointdamageoccurswhenthelimfosit,macrofagandfibroblas
    areoccurinthesynovialtissues

    Inflammationandoclusiofartery

    Irregulartissue

    Breakdownthecartilago

    progressivedisabilityinmovement
    Thediseaseoftenbegins
    slowly,usuallywithonly
    minorjointpain,stiffness,
    andfatigue.

    RAusuallyaffectswrists,
    fingers,knees,feet,and
    ankles.
    SYMTOPMATHOLOGY
    Mainsymptoms:
    Morningstiffness,whichlastsmorethan1hour,iscommon.
    Jointsmayfeelwarm,tender,andstiffwhennotusedforanhour.
    Jointpainisoftenfeltonthesamejointonbothsidesofthebody.
    Overtime,jointsmaylosetheirrangeofmotionandmaybecome
    deformed.

    Othersymptoms:

    Chestpainwhentakingabreath(pleurisy)
    Dryeyesandmouth(Sjogrensyndrome)
    Eyeburning,itching
    Noduleundertheskin(usuallyasignofmoreseveredisease)
    Numbness,tingling,orburninginthehandsandfeet
    Sleepdifficulties
    DIAGNOSIS
    Sevendiagnosticcriteria:
    1. morningstiffness,
    2. arthritisofthreeormorejointareas,
    3. arthritisofthehandjoints
    4. symmetricarthritis,
    5. rheumatoidnodules,
    6. elevatedlevelsofserumrheumatoidfactor,
    7. Radiographicchanges.

    thefirstfourcriteriamustbepresent
    foraminimumofsixweeksbeforeadiagnosisofrheumatoidarthritis
    canbemade

    WecanuseCreactiveprotein(CRP),EritrositSedimentRate(ESR),Joint
    xraytohelpusmakediagnosis
    THERAPHY/TREATMENT

    Nonsteroidalantiinflammatorydrugs(NSAIDs)
    Corticosteroids(glucocorticoid)
    Diseasemodifyingantirheumaticdrugs(DMARD):methotrexate

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