Intro Cvs Kbi
Intro Cvs Kbi
Intro Cvs Kbi
by
M. Rasjad Indra
Main function
Serve a transportation for:
Supplying nutrition and oxygen to tissues
Elimination of metabolic end products from tissues
Hormones & other chemical substances as a
intercellular communication mediator
Blood flow
Total blood vessel
resisstance
Blood volume
Vasoconstriction /
dilatation
Blood pressure
Cardiac pumping
Cardiac
cycle
Cardiac muscle
contraction
Cardiac muscle &
cunductive system
Vascular smooth
muscle
Action potential
P
Q
R
r = radius
d= blood viscosity
l = blood vessel length
Pr
Poiseuille law: Q
8l
Blood pumping
Arteri:
Ateriole:
Capillary:
Venula:
Vein:
Volume (ml)
Volume (%)
Sistemic circulation
4200
84,0
300
6,0
Small artery
400
8,0
Capilary
300
6,0
Small vein
2300
46,0
Large vein
900
18,0
Pulmonar y circulation
440
8,8
Artery
130
2,6
Capillary
110
2,2
Vein
200
4,0
Heart
Total
360
5000
360
5000
7,2
100,0
7,2
100,0
Parameter
Aorta
Small artery
Arteriole
Capillary
V. Cava
Number
8000
2 x 107
1 x 1010
Radius
1,13,cm
0,5 mm
15 m
3 m
1,38 cm
Diameter
4 cm2
6 cm2
Total diameter
4 cm2
63 cm2
141 cm2
2827 cm2
6 cm2
83 ml/second
83 ml/second
83 ml/second
83 ml/second
83 ml/scnd
0,003 cm/sc
14 cm/scnd
0,01 ml/secnd
8 x 10-9 ml/sc
83 ml/scnd
83 ml/second
4 x 10-6 ml/scnd
Diameter (cm2)
Aorta
Small Arteries
2,5
20
Arteriole
40
Capillaries
Venule
2500
250
Small Vein
80
Vena cava
Blood Flow
The blood flow going slower because of
decreasing blood pressure and increasing total
diameter of blood vessels
In aorta: 33 cm / second
In capillary: 0,3 mm / second
Capillaries length: 0,3 1 mm blood stay in
capillary 1 3 seconds
Very short time for fluid exchange between
plasma and interstitial !!!!
Blood pressure
3 Basic Principles of
Cardiovascular Function
1. Tissue blood flow is regulated in