Intra Uterin Fetal Death
Intra Uterin Fetal Death
Intra Uterin Fetal Death
DEATH
Dr.P.S.Hettipathirana
MBBS(COL),MD(Obs & Gyn),MRCOG(UK)
Senior lecturer/ Consultant Obstetrician & Gynaecologist
Definition:
Baby delivered with no signs of life, known
Causes
Fetal
Placental
Maternal
Unexplained
Causes
Fetal causes
Chromosomal & Genetic anomalies
Birth defects
Non immune hydrops
Infections CMV,rubella, parvo B19,Herpes,malaria
Cord accidents
Placental
Abruption
Placental insufficiency
Intrapartum asphyxia
Twin to twin transfusion Syndrome
Chrioamnionitis
Causes
Maternal
Antiphospholipid antibody
Diabetes
Hypertention
Trauma
Abnormal labor Sepsis
Acidosis/ Hypoxia
Uterine rupture
Post term pregnancy Drugs
Thrombophilia Cyanotic heart disease
Epilepsy Severe anemia
Unexplained - majority
Diagnosis
Absence of uterine growth
Loss of fetal movement
Absence of fetal heart Pinnard/CTG
Disappearance of the signs & symptoms of
pregnancy
Imaging Spalding sign
Diagnosis
History
Family history
Recurrent abortions
deep vein thrombosis/ Pulmonary emboloism
Congenital anomalies, Abnormal karyotype
Maternal History
Maternal medical conditions
Deep vein thrombosis/Pulmonary embolism
Diabetes mellitus
Hypertention
Thrombophilia
SLE,Autoimmune disease
Severe Anemia
Epilepsy
Consanguinity
Malformation
Degree of maceration
Colour - pale,plethoric
Umbilical cord
MANAGEMENT
Breaking the bad news
Delivery
Investigation cause/complications
Psychological counseling
Rh negative Anti D immunoglobulin
Investigation
Cause
FBC
Blood Gp & antibody screen
HbA1 C
Kleihauer Betke test look for feto maternal haemorrhage
Serological screening for Rubella,CMV, Toxoplasma
Syphylis, Herpes & Parvovirus
Thrombophilia screening (antithrombin III,Protein C & S , factor IV
leiden, lupus anticoagulant, anticardiolipin antibodies)
Fetal and placental autopsy
Maternal Complication
Coagulation tests
-DIC
DELIVERY
Immediate delivery
sepsis,ruprured membranes,placental abruption,eclampsia
Expectant approach:
80% goes into spontaneous labour within 2-3 weeks
Risk DIC if wait for > 4 weeks
Emotional burden
Active approach:
emotional burden, risk of chorioamnionitis, and risk of DIC (if >5wks)
Induction of labour can be initiated at any time.
DELIVERY
Always try to achieve vaginal delivery
Unless contraindicated eg : Placenta previa
Methods
ARM & syntocinon
Prostaglandin
Misoprostol
Post partum
Suppression of Lactation
Bromocriptine
Cabergoline
THANK YOU