Back To Medical School: - Anorectal Disorders

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Back to medical school

-anorectal disorders

Ian Botterill, Dept Colorectal Surgery


Leeds General Infirmary
Wide variety of pathologies
• congenital / acquired

• benign / malignant
• traumatic
• infective / inflammatory
• gender / age related
Common symptoms of ano-rectal
disorders
• bleeding
• anal pain
• itch
• faecal leakage / hygiene problems
• swelling
• discharge
Examination
• abdomen
• groins (lymph nodes)
• dermatoses
Ano-rectal examination

• chaperoned
• relaxed patient
• left lateral
• good light
• knee elbow position
• use pt’s hand to elevate
right buttock
• +/- anoscopy in 1y care
Ano-rectal examination

• External appearance • Digital examination


-skin condition -sphincter tone
-swellings -squeeze pressure
-soiling / discharge -cervix / prostate
-perineal descent -coccyx
-scars -retrorectal space
-rectocoele
Anatomy
Haemorrhoids
• Symptoms:
- anal canal bleeding, pruritus, swelling, pain
Haemorrhoids
• Classification
- 1y: bleed, do not prolapse
- 2y: prolapse & reduce spontaeously
- 3y: prolapse & require manual reduction
- 4y: prolase, not reducible
Cause of haemorrhoidal problems

• altered bowel habit


• raised intra-abdominal pressure
• straining
Treatment of haemorrhoids
• Diet
-five helpings fibre / d
• Out-patient
-injection sclerotherapy
-banding
-photocoagulation
Surgical treatment
• For 3rd / 4th degree haemorrhoids

• Open haemorrhoidectomy
• Closed haemorrhoidectomy
• Ligasure haemorrhoidectomy

• Stapled haemorrhoidopexy (PPH)


Results of haemorrhoidectomy
• >90% daycase
• least initial pain
-stapled haemorrhoidopexy
-Ligasure haemorrhoiodectomy
• quickest return to work:
-stapled haemorrhoidopexy
-Ligasure haemorrhoidectomy
• most costly: PPH / ligasure
• lowest recurrence (prolapse) ; conventional
Complications of
haemorrhoidectomy
• Local
- stenosis
- faecal leakage
- recurence
- bleeding
- retention of urine

• severe perineal sepsis (esp IDDM &


immunosuppressed)
Painful prolapsed haemorrhoids

• natural history (worst pain days ~ 3-7, then settles)

• most resolve with conservative Rx


- lactulose / topical anaesthetic creams / ice / paracetamol & NSAIDs /
relief of anal spasm (GTN or diltiazem)
- failure to resolve > haemorrhoidectomy
- refer gangrenous or those that fail to settle

• interval haemorrhoidectomy if still problematic


Anal skin tags

Sx: anal swelling / hygiene problems


Diagnosis: perineal examination alone
Differential: Crohn’s disease / anal warts
Rx: reassurance / excision
Rectal mucosal prolapse & full
thickness rectal prolapse
Rectal mucosal prolapse
• result of straining
• associated with pruritus ani / mucous
discharge
• diagnosis @ anoscopy
• Rx
- dietary correction
- advised to avoid straining at stool
- injection sclerotherapy
Ano-rectal sepsis

Sx: perineal pain (throbbing), possible prior history of similar


Exam: tender fluctuant mass +/- discharge, may be toxic
Beware: diabetics (risk of rapidly progressive infection & Fournier’s gangrene)
skin necrosis (possible Fournier’s gangrene)
anal spasm & throbbing pain (inter-sphincteric abscess)
Treatment: I&D
Fistula in ano

~ 30-40% of all perineal sepsis once drained goes on to develop


a fistula
~ 80-90% of perineal sepsis that yielded enteric organisms will
develop a fistula
Fistula in ano
• 95% cryptoglandular
- ie origin in ano-rectal crypts at dentate line

• 5% rarities
- Crohn’s
- TB
- hidradenitis suppurativa
- traumatic
- malignancy
- complicated diverticular disease
- radiation
- anastomotic leakage
Classification
Inter-sphincteric 70%
Trans-sphincteric 25%
Supra-sphincteric ~5%
Extra-sphincteric <1%

Simple v. complex

‘Complex’:
-branching tracts / 2y tracts
-associated abscess
-associated pathology
Goodsall’s rule

External opening posterior to 3-9


oclock position open in posterior
midline of the anal canal

External opening anterior to 3-9 oclock


position open radially in the anal canal

~80-90% accurate
Management of fistula in ano

Strike a balance between


-cure of fistula
-prevention of further anorectal abscess
-preservation of continence
Management of fistula in ano
• Divide tissues overlying track ( to allow healing by 2y
intent)
- lay open
- cutting seton

• Occlude internal opening & provide external drainage

- anal fistula plug


- rectal or anal advancement flap

• Prevention of further ano-rectal sepsis


- draining seton
Anal fissure
• ‘focal linear deficiency of anal mucosa’

• posterior > anterior

• acute v. chronic
-chronic: IAS exposed , > 6/52, keratinisation

• simple v. complex
Anal fissure
Anal fissure management
• stool softeners
• dietary advice
• topical LA

• chemical sphincterotomy
-topical
-injected
• surgical sphincterotomy
Anal fissure surgery through the
ages
• anal stretch
• lateral sphincterotomy

• chemical sphincterotomy
- topical
- injectable
Anal fissure treatment
• GTN 40-50% successful
s/e: severe headaches
• Diltiazem 60-80% successful
s/e: nil generally
• Botox 60-90% successful
s/e transient minor leakage
• Sphincterotomy 98% successful
s/e 2% passive leakage
Proctitis
• Biopsy mandatory (with exception of prior
prosate / cervical brachytherapy)

• UC / Crohn’s / indeterminate / infective

• Stool culture

• Biopsy prior to starting suppositories

• Suppositories often preferable to oral therapy


Pilonidal sinus / & abscess

Abscess often deep-seated – do not respond to antibiotics


Pilonidal sinus disease
Z plasty

Uli Szymanovski
Developed ‘Z’ plasty wound closure
Rhomboid flap

Healing by 1y intention ~90% of time as with Z plasty


Healing by 2y intent
Healing using Vac Therapy
Perianal haematoma
• Thromobosis of superficial haemorrhoidal
veins

• Discrete circular lump at / beyond anal


verge

• Incise & drain


Pruritus ani

Night > day


Rule out coexistent dermatoses / renal failure / liver disease
If fungal disease suspected > skin scrapings
Ano-rectal examination & proctoscopy.
Treat ano-rectal pathology (haemorrhoids / faecal incontinence / anal
tags etc).
Pruritus treatment
• Avoid synthetic / tight underwear
• Avoid perfumed soaps etc
• Avoid scratching
• Use hairdryer to dry skin
• Avoid steroid creams
• Treat anal pathology / diarrhoea
• Dermatology involvement

• Methylene blue injections > ~80% successful


- s/e occasional cellulitis / ulcer /
incontinence
Faecal incontinence
- understand continence first!
• Brain / higher centres
• Spinal cord
• Reflex arcs
• Pudendal nerves
• Ano-rectal sensation ‘sampling’
• Stool consistency
• Rectal compliance
• Anal sphincter complex
Faecal incontinence
• Causation

• Obstetric injury (8-30% sphincter injury rate at childbirth)

• Post-surgical
• Faecal impaction
• Neuropathy / MS / Parkinson’s
• Poor mobility / impaired cognition
• Diarrhoea
• IBS / rectal non-compliance
Assessment of faecal incontinence
• History
• Examination

• Endoanal USS (sphincter injury)

• Anorectal manometry (rest & squeeze strength)

• Pudendal nerve terminal latency (sensation)


Assessment of incontinence
• Cleveland clinic score - severity of soiling - frequency of
soiling - use of pads - lifestyle disruption

• History of back injury / neurolgical disorder

• Urinary incontinence

• Saddle anaesthesia
Treatment incontinence
• dietary measures
• treat diarrhoea / impaction / IBS
• non-operative
- collagen injections
- anal plug
• sacral nerve stimulation
• sphincter repair
• artificial sphincters
• graciloplasty
Anal stenosis
• Post-surgical
• Cancer
• Crohn’s
• Previous chronic anal fissure

• Radiation
• Systemic sclerosis

• Need EUA to assess all these


Anal cancer

Sx: itch, bleeding, pain (if below dentate line), swelling,


ulcer, groin node
Exam: hard, irregular, friable area. Groin nodes possible. ?
Coexists with anal warts
Differential: haemorrhoids, anal fissure, anal warts, STD
Diagnosis: EUA & biopsy
Anal cancer
-treatment
• Chemo-radiotherapy
• Ongoing perineal surveillance
• Average local control ~ 70%
• Average cure ~ 70%
• Salvage surgery for recurrence
- APER with rectus flap to perineum

• Rarely is local excision alone sufficient


Hidradenitis suppurativa

Superficial fistulating condition ass’d with chronic skin sepsis


Axillae > groins > perineum
Clinical diagnosis (+/- biopsy) – typically have disease elsewhere
Rx: drain sepsis / rotating antibiotics / infliximab / stop smokng
Anal papillae

Sx: nil (asymptomatic finding typically)


Diagnosis: at anoscopy
Biopsy: rarely required
Treatment: leave alone
AIDS & the perineum
• Wide variety of pathology
- fissures / abscesses / fistulae / infections / anal
cancer / cutaneous lymphoma
- florid warts
- pruritus
- incontience

• General principle
- suspect immunocompromise
- culture / biopsy
- avoid agresssive surgery
- treat in conjunction with Infectious Diseases
/ Sexual Health
AIDS

HSV
Other perineal problems
-pressure sores

Post-sacral
Over ischial tuberosity
Normally have clear cut antecedant history
summary
• diverse pathology
• high degree of overlap between 1y and 2y
care
• refer bleeding
• refer ‘odd-looking’ lesions

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