Bimed 09

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Embryonic development

The embryonic development of any animal starts


from the fertilized egg (zygote) which usually
passes through three main stages which are:
1) Cleavage, 2) Gastrulation and
3) Organ formation (organogenesis).
1) Cleavage:
After fertilization, the zygote divides repeatedly
by a series of mitotic divisions.

Zygote vertical 2-blastomere stage


at right angle to the horizontal
1st division 4-blastomere stage
double vertical
8-blastomere stage 16-blastomere stage
double horizontal
32-blastomere stage (morula)

64-blastomere stage 128-blastomere stage


A blastula
The blastula
@ It is a hollow structure formed at the end of
cleavage process.
@ Its wall is consisted of a single layer of cells.
These cells are differentiated into micromeres at
the animal pole and macromeres at the vegetal
pole.
@ The fluid filled cavity in its center is termed
blastocoel.
This blastocoel is not connected to the exterior.
2) Gastrulation

The gastrula
@ It is an elongated structure formed at the end of
gastrulation process by flattening and invagination of
macromeres of blastula.
Invagination continues until the macromeres come in direct
contact with micromeres.
So, the blastocoel is disappeared while a new cavity is
formed.
@ Its wall is formed from a double layers of cells.
The outer layer which is formed from micromeres (is known
as the ectoderm) while the inner layer is formed from the
macromeres (the endoderm forms).
@ It has a cavity that called archenteron which is connected
to the exterior through an opening called a blastopore.
3) Organ formation (organogenesis):
Zygote

Blastula

Gastrula

Ectoderm Mesoderm Endoderm

Epidermis Brain & Notochord


Embrygonic gut
Somites
and nervous
associated system Mesenchyme
structures Outer
(loose & covering Inner Inner lining
e.g. skin, migrating lining of of
hair, nails of the respiratory
Muscles
… etc.
cells) internal digestive tract
organs tract
Dermis Circulating Bones & Glands
(inner system cartilage including
skin layer (heart & liver &
blood pancreas
Excretory Gonads
vessels)
system
Histology
Types of tissues

Epithelial Connective Muscular Nervous


tissues tissue tissues tissues

Origin Ectoderm, mesoderm Mesoderm, Ectoderm,


endoderm or
mesoderm

Matrix Small Huge


(intercellu- amount amount
lar
substance)

Basement Has a Has not


membrane basement basement
membrane membrane
Epithelial tissues
According to their function

Covering epithelium Glandular epithelium Neuro-epithelium

According to the number of layers of cells

Simple epithelium Pseudostratified epithelium Stratified epith.elium


(one layer) (all cells are not attached to the (more than one layer)
free surface
According to the shape of cells &
the presence or absence of cilia on
the free surface Lining blood vessels
1- Simple squamous
epithelium Thyroid glands

2- Simple cuboidal
epithelium

3- Simple columnar Lining


digestive Lining
epithelium
tract of ovisac &
Bufo oviduct
4- Simple columnar of Bufo
ciliated epithelium
Epithelial tissues
According to their function

Covering epithelium Glandular epithelium Neuro-epithelium

According to the number of layers of cells

Simple epithelium Pseudostratified Stratified


epithelium epith.elium

According to the presence or absence of


cilia on the free surface

1- Pseudostratified
columnar epithelium
e.g. male urethra

2- Pseudostratified
ciliated columnar
epithelium

e.g. lining trachea


Covering epithelium Glandular epithelium Neuro-epithelium

Simple epithelium Pseudostratified Stratified


epithelium epith.elium
According to the shape of the cells & the
presence or absence of cilia on the free surface

1- Stratified squamous
epithelium
e.g. Epidermis of the
skin
2- Stratified cuboidal
epithelium
e.g. Cloaca of the toad
3- Stratified columnar
epithelium
e.g. Conjunctiva of the
eye
4- Stratified ciliated
columnar epithelium
e.g. lining vas
deferens
5 Transional
epithelium
e.g. lining urinary
bladder
Covering epithelium Glandular epithelium Neuro-epithelium
According to the presence or
absence of ducts Exocrine glands
Endocrine glands -With ducts-
-without ducts)-
(duct glands)
(ductluss glands) According to the number of cells

e.g. pituitary, thyroid, Unicellular


Multicellular glands
parathyroid, adrenal, glands
- Moretothan
According the one cell
duct
gonads (testes & -One cell-
ovaries), islets of e.g. goblet cells system
Compound
Langerhans, glands
According to the shape Simple glands
of secretory portion (have one (have duct
duct) system)
1- S. tubular
glands
e.g. crypts of Lieberkühn
2- S. coiled tubular
glands
e.g. sweat glands
3- S. branched tubular
glands
e.g. gastric glands
4- S. alveolar glands
e.g. mucous & poisonous
gland in skin of Bufo
5- S. branched alveolar
glands
e.g. sebaccous glands
Covering epithelium Glandular epithelium Neuro-epithelium

Endocrine glands Exocrine glands


(ductluss glands) (duct glands)
According to the number of cells

Unicellular
e.g. pituitary, thyroid, Multicellular glands
glands
parathyroid, adrenal, e.g. goblet cells
gonads (testes &
ovaries), islets of Simple glands Compound
Langerhans, …. Etc. According to theglands
shape of
secretory portion
1- C. tubular
glands
e.g. lacrimal
glands
2- C. alveolar
glands
e.g. salivary gland
3- C. tubulo-
alveolar glands
e.g. mammary
gland & exocrine
portion of pancreas
4- Reticular glands
e.g. liver of
mammals
‫مع أرق تحياتى وأمنياتى لكم‬
‫جميعا بالتوفيق والتفوق‬

‫ا‪.‬د‪ .‬شــــبل شــــعلن‬

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