Presented By:dr - Anita Chaudhari Roll No: 2
Presented By:dr - Anita Chaudhari Roll No: 2
Presented By:dr - Anita Chaudhari Roll No: 2
Anita Chaudhari
Roll No : 2
INTRODUCTION
It is thus-
A (acquired) : got from others
HIV is:
Human – isolated to the human species
Agent factors
a.Agent—HIV is 1/10,000th of mm in dia.It has unique ability to destroy
humanT4 helper cells,spreads throughout body & passes through
blood brain barrier & can destroy brain cells.
b.Reservoir of infection--- They are cases & carriers.Once infected
virus remains in body lifelong.
Symptomless HIV infected carrier can infect others.
a.Source of infection---The virus is in greatest concentration in
blood ,semen,and CSF.Lower conc. Detected in tears, saliva, breast
milk, urine, cervical and vaginal secretions.
Only blood and semen have been shown to transmit the virus
EPIDEMIOLOGICAL FEATURES
Host factors
a.Age—In sexually active persons of age group 20-49 years.
b.Sex---Sexual practices like multiple partners, anal intercourse ,
male homosexuality,prostitution, increases risk.
c. High risk group —male homosexuals & bisexuals, prostitutes ,
iv drug abusers, blood & blood product transfusion of HIV
infected.
d.Immunology —The virus reproduces and destroys WBC’s(T
helper cells),thus reducing the immunity of the body.
MODE OF TRANSMISSION
SEXUAL TRANSMISSION
Infected person’s blood, semen, are rich in
HIV.
However tears, saliva, sweat, urine do not
pose danger
Most easily by unprotected sexual
intercourse.
MODE OF TRANSMISSION
BLOOD CONTACT
Transfusion of infected
blood or blood products .
Sharing of needles
& syringes by HIV drug addicts .
MODE OF TRANSMISSION
1. Initial infection —
HIV infected have no symptom for first 5 years.Look healthy,feel
well but can transmit the virus.
2. Asymptomatic carrier state---
Infected people have antibodies but no signs of desease.
3. AIDS related complex---
illness caused by damage to immune system show one or more
clinical signs( diarrhoea,fever,loss of weight,cough,enlarge
spleen,fatigue,G.weakness,etc.)
4. AIDS---
End stage of HIV infection.No. of infections occur at this
stage.Due to uncontrol infection.
CLINICAL DIAGNOSIS
Minor signs---
Persistent cough (more than1 month)
Oral candidiasis
SPOT TEST
This is simple rapid test for finding out HIV status.
Rarely chances of false positive report & hence positive report should be confirmed by
doing ELISA test.
ELISA TEST
The infection can only be detected by doing
blood test i.e. ELISA HIV antibody test.
WESTERN BLOT(WB) TEST
Specialized and costly confirmatory test for HIV.
Done to confirm positive ELISA or SPOT test report.
LABORATORY DIAGNOSIS
Very costly tests & done only in affording patients who are willing to
start anti-HIV (antiretroviral) drugs.
SAFE MOTHERHOOD
HIV may pass from infected mother to
foetus through placenta ,during delivery
or by breast feeding.
GENERAL CARE
Embarrassing
Coughing or sneezing
Swimming pools
HOW HIV--NOT TRANSMITTED
Sharing clothes
Patient caring
ANTI RETROVIRAL TREATMENT
SYMPTOMATIC TREATMENT
Early treatment of common problems like fever, cough, diarrhoea etc. from family doctor .
Early treatment of opportunistic infections like TB etc.
SPECIFIC ANTI-RETROVIRAL TREATMENT
HIV suppressants drugs should be used as there is no vaccine or cure available.(The drug should be as per Doctors
advice).
For eg.
For accidental pricks - AZ3 200 mg tds + Lamivudin 150 mg bd for 4 weeks