Acute Coronary Syndrome
Acute Coronary Syndrome
Acute Coronary Syndrome
Acute coronary syndrome usually occurs as a result of one on three problems, STEMIand NSTEMI,unstable angina, and elevated serum cardiac markers .
MYOCARDIAL INFRACTION
AMI is also know as heart attack, coronary occlusion, or simply a coronary, characterized by the formation of localized necrotic areas with in the myocardium. The sudden occlusion of a coronary artery and abrupt cessation of blood and oxygen flow to the heart.
UNSTABLE ANGINA
Unstable angina is a paroxysmal chest pain triggered by predictable degree of exertion or emotion ,which may occur at night. It attacks characteristically increase in number, duration, and severity over time.
ETIOLOGY
Smoking Hypertension Elevated serum cholesterol levels Obesity Diabetes mellitus Physical inactivity Alcoholism Oral contraceptive pills Response to stress Inflammatory responses
PATHOPHYSIOLOGY
Formation of thrombus
ischemia
Coronary blood supply less than demand Myocardial cell death Decreased contractibility
Altered depolarization of myocardium Release of lysosomal enzyme Anaerobic glycosis Myocardial irritability
Decreased irritability
Stimulation of sympathetic nervous system
Increased preload
Increased CVP&PC WP
Decreased LV function
vasoconstriction
CLINICAL MANIFESTATIONS
Chest pain Dyspnoea Diaphoresis Nausea and vomiting Palpitations Fatigue and lethargy Syncope Anxiety Abdominal pain fever
DIAGNOSTIC MEASURES
History collection Electrocardiogram findings Laboratory test (serum cardiac makers) CK MB Myoglobin Troponin LDH Leukocytosis Coronary angiography
CONT
Position emission tomography Magnetic resonance imaging Echocardiography Tran esophageal echocardiography Chest x-ray
ECG CHANGES
COMPLICATIONS
Dysrhythmias Heart
failure Cardiogenic shock Pulmonary embolism Pericarditis Recurrent myocardial infarction Ventricular aneurysm Papillary muscle dysfunction Dressler syndrome
MEDICAL MANAGEMENT
Goals of medical management Initiating prompt care Reducing pain Delivering successful treatment for the accute pain and reperfusion of the myocardium Preventing complications Rehabilitating and educating the client and significant others
EMERGENT PCI
DRUG THERAPY
IV nitroglycerin Morphine sulphate adrenergic blockers Angiotensin converting enzyme inhibitors Antidysrhythmic Drugs Cholesterol- lowering drugs Stool softners Nutritional therapy
Percutaneous transluminal coronary angioplasty(PTCA) Directional coronary atherectomy (DCA) Intracoronary stents Laser ablation Trans myocardial revascularization
PTCA
Thank you.