Gerald_D._Aurbach

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Gerald D.

Aurbach
Gerald D. Aurbach (March 24, 1927 – November 4,
1991) was an American medical scientist noted for his Gerald D. Aurbach
studies of parathyroid diseases, bone metabolism and Born March 24, 1927
calcium homeostasis.[1][2] Aurbach was the first Cleveland, Ohio
researcher to produce a hormone produced by Died November 4, 1991 (aged 64)
parathyroid glands. Charlottesville, Virginia
Alma mater University of Virginia (Bachelor
Aurbach began studying PTH as a medical student in
Degree, 1950; MD, 1954)[1]
the lab of Dr. William Parson. He continued this
research as a fellow as Tufts University School of
Medicine in the lab of Ted Astwood. Here, he was the first to isolate PTH using phenol extraction, and in
1959 he published a landmark paper on this discovery. In 1959, he joined the lab of William Jakoby at the
National Institutes of Health, and two years later he established his own lab in the Metabolic Diseases
Branch. He became chief of the branch in 1973, and remained at the institute for the remainder of his
career.[1]

He determined that parathyroid hormone acts through cyclic AMP, and demonstrated that
pseudohypoparathyroidism is a disorder of the parathyroid hormone receptor complex.[2] He also
characterized several hereditary diseases related to hyperparathyroidism.

In 1973, he was named director of the metabolic diseases branch of the National Institutes of Health, and
was elected to the National Academy of Sciences in 1986.[2]

Aurbach was killed in 1991 while visiting the University of Virginia in an apparent homicide by a stone
thrown from a car.[2]

Notable awards and distinctions


1960: the John Horsely Memorial Award from the University of Virginia[1]
1968: the Andre Lichiwitz Prize from France[1]
1981: the William F. Neuman Award of the American Society for Bone and Mineral
Research[1]
1983: the Gairdner Foundation International Award[1]
1986: elected to the National Academy of Sciences[1][2]
1985: the Edwin B. Astwood Award from the Endocrine Society[1]
1988: the Public Health Service Distinguished Service Medal[1]

Memorials
Both the Endocrine Society and the American Society for Bone and Mineral Research have established
memorial lectures in his name.[1] The University of Virginia School of Medicine established the Gerald
D. Aurbach Professorship in Endocrinology, and in 2002, dedicated a new medical research building in
his name.[1]

References
1. National Academy of Science;Biographical Memoirs: V. 90 (2009) GERALD DONALD
AURBACH;BY IRA PASTAN (http://www.nap.edu/openbook.php?record_id=12562&page=3)
2. Gerald Aurbach, 64, U.S. Health Researcher November 06, 1991 (https://www.nytimes.com/
1991/11/06/obituaries/gerald-aurbach-64-us-health-researcher.html)

External links
Ira Pastan, "Gerald Donald Aurbach", Biographical Memoirs of the National Academy of
Sciences (2007) (http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/a
urbach-gerald-d.pdf)

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