DEPARTMENT OF CHEMISTRY

UNIVERSITY OF LUCKNOW, LUCKNOW

Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
Semester V
Paper Paper Title Type Credits Internal Univ Total
Assess Exam Marks
ment
Paper 9 Organic Chemistry 2 Theory 4 25 75 100

Paper10 Chemistry Practical 3 Practical 4 25 75 100

Paper 11 x Analytical Chemistry Chemistry 4 25 75 100

Elective 1
Paper 11 y Chemical Energetics Chemistry
and Radiochemistry Elective 2
IS Chemistry Internship Theory 4 - 100 100

P9’ Second major subject Theory 4 25 75 100

P10’ Second major subject Theory 4 25 75 100

Total Credits 24 600

Choice will be given to students to opt in which major subject they wish to do internship in
semester V and minor project in semester VI

22
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)

Organic Chemistry 3
Semester V Paper 9 (P9) Credits 4
Course outcome
Students on completion of the course will develop a comprehensive
knowledge of
CO-1 The organometallic compounds such as Grignard reagent which have
been widely used on both laboratory and commercial scale and is one of the
most common organometallic reagents used for the formation of carbon–
carbon bonds. Organosulphur compounds which have therapeutic use and
pharmacology
CO-2 Carbohydrate, its classification and use in the food industry etc.
CO-3 Protein, aminoacid and peptides. Chemical structure of RNA and DNA.
CO-4 Various polymers, their method of polymerization and their use in
industry
Unit I
Organometallic Compounds: Organomagnesium compounds: the Grignard
reagents, formation, structure and chemical reactions. Organolithium
compounds formation and reactions. Nomenclature, structural, features,
methods of formation and chemical reactions of organosulphur compounds
Introduction and Synthesis of the representative drugs of the following
classes: analgesics agents, antipyretic agents, anti- inflammatory agents
(Aspirin, paracetamol); antibiotics (Chloramphenicol); antibacterial and
antifungal agents (Sulphonamides; Sulphanethoxazol, Sulphacetamide);
antiviral agents (Acyclovir), Central Nervous System agents (Phenobarbital).
Heterocyclic compounds
Introduction: Molecular orbital picture and aromatic characteristic of pyrrole,
furan, thiophene and pyridine, methods of synthesis and chemical reactions
with particular emphasis on the mechanism of electrophilic substitution.
Mechanism of nucleophilic substitution reaction in pyridine derivatives.
Comparison of basicity of pyridine, piperidine and pyrrole. Introduction to
condensed five and six membered heterocycles. Preparation and reactions of
indols, quinoline and isoquinoline with special reference to Fisher Indols
synthesis, Skraup synthesis and Bischler – Nepieralski synthesis. Mechanism
of electrophilic substitution reaction of indole, quinoline and isoquinoline.
Unit II
Carbohydrates: Classification and nomenclature, configuration and
conformation of monosaccharides, Erythro and threo diastereomers,
mechanism of osazone formation, interconversion of glucose and fructose,
chain lengthening and chain shortening of aldoses. Formation of glycoside,
ethers and esters. Determination of ring size of monosaccharides. Cyclic
structure of D(+) glucose. Mechanism of mutarotation, structure of ribose and
deoxyribose. An introduction to disaccharides (maltose, sucrose, lactose) and

23
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
polysaccharide/starch and cellulose) without involving structure determination.
Concept of glycosidation.
Unit III
Amino Acids, peptides, proteins and Nucleic Acids: Classification, structure
and stereochemistry of amino acids. Acid-base behaviour, isoelectric point
and electrophoresis, Preparation and reaction of a amino acids, structure and
nomenclature of peptides and proteins. Classification of proteins, peptides
structure determination, and group analysis. Selective hydrolysis of peptides.
Classical peptide synthesis, solid phase peptide synthesis. Structure of
peptides and proteins level of protein structures. Protein
denaturation/renaturation.
Nucleic Acids: Introduction - Classification of nucleic acids Ribonucleosides
and Ribonucleotides. The double helical structure of DNA.
Unit IV
Synthetic Polymers: Addition or chain-growth polymerization, Free radical
vinyl polymerization, ionic vinyl polymerization, Ziegler-Natta polymerization
and vinyl polymers. Condensation or step growth polymerization. Polyesters,
polyamides, phenol formaldehyde resins, urea formaldehyde resin, epoxy
resins and poly urithanes. Natural and synthetic rubbers.
Synthetic Dyes: Colour and constitution / electronic concept classification of
dyes. Chemistry and synthesis of Methyl orange, conge red, Malachite green,
crystal violet, phenophthalein, Fluorescin, Alizarin and Indigo.

Books Suggested (Theory Courses)

a) Organic Chemistry, Morrison and Boyd, Prentice Hall.
b) Organic Chemistry, L.G. Wade Jr. Prentice Hall
c) Fundamentals of Organic Chemistry Solomons, John Wiley.
d) Organic Chemistry, Vol. I, II, III, S.M. Mukherji, S.P. Singh and R.P.
Kapoor, Wiley Eastern Ltd. (New Age International).
e) Organic Chemistry, F.A. Carey, McGraw-Hill Inc.
f) Introduction to Organic Chemistry, Streitwiesser, Hathcock and
Kosover, Macmillan.
g) Organic Chemistry, Vol. I, II, I.L. Finar

24
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
Chemistry Practical 3
Semester V Paper 10 (P10) Credits 4
Course Objective
The objectives of this course are to acquisition of skills in General Chemistry
and Physical Chemistry. To develop the ability to correlate the chemical and
physical properties of elements. To establish the link between theory and
laboratory practice by conducting laboratory experiments. To acquire
expertise in chemistry laboratory in handling of reagents and solvents as well
as in analytical techniques.
Course Outcome
After completing the course, the student will be able to: -
CO-1 Having acquired knowledge to handle instruments and its calibration.
CO-2 Explain the structure and bonding in molecules / ions and predict the
structure of molecules / ions. –
CO-3 Explain selected crystal structures, explain and perform calculations of
the lattice enthalpy of ionic compounds. –
CO-4 Having knowledge of Beer Lamberts law
CO-5 To separate compounds chromatographically.
CO-6 Able to make solutions accurately to perform conductance experiments.
CO-7 To understand making circuit connections and taking observations.
A: Inorganic Chemistry
I. Synthesis and Analysis
a. Preparation of potassium trioxalatoferrate (III),
K3[Fe(C2O4)3] and determination of itscomposition by
permagnometry.
b. Preparation of Ni-DMG complex, [Ni(DMG)2]
c. Preparation of copper tetraammine complex,
[Cu(NH3)4]SO4
d. Preparation of cis-and trans-bisoxalatodiaqua chromate
(III) ion.
II. Colorimetry
a. To verify Beer-Lambert law for KMnO4/K2Cr2O7 and
determine the concentration of thegiven solution.
b. Determination of Fe3+ content by thiocyanate method.
III. Solvent Extraction
a. Separation and estimation of Mg(II) and Fe(II) Ion
Exchange Method
b. Separation and estimation of Mg(II) and Zn(II).

25
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
IV. Chromatography
a. Chromatographic separation of metal ions.
B: Organic Chemistry
I. Mixture Analysis
a. Organic mixture separation and identification (two
components)
II. Preparation
b. One step preparation.
C: Physical Chemistry
I. Electrochemistry
a. To determine the strength of the given acid
conductometrically using standard alkali solution.
b. To determine the solubility and solubility product of a
sparingly soluble electrolyte conductometrically.
c. To determine the ionisation constant of a weak acid
conductometrically.
II. Refractometry and Polarimetry
a. To verify law of refraction of mixtures (e.g. of glycerol and
water) using Abbe’s refractometer.
b. To determine the specific rotation of cane sugar solution
by polarimeter.
III. Molecular Weight Determination
a. Determination of molecular weight of a non-volatile solute
by Rast method/Beckmann freezing point method.
b. Determination of the apparent molecular weight of non
volatile solute at different concentration and determine
Van’t Hoff factor by ebullioscopy.
IV. Colorimetry
a. To verify Beer-Lambert law for KMnO4/K2Cr2O7 and
determine the concentration of the given solution of the
substance.
Books Recommended
a) Chemistry Practical by S. Giri, D.N. Bajpai and O.P. Shukla, S. Chand
Publication.
b) Practical Chemistry Volume 1-3 by Fateh Bahadur, Vishal Publication
c) Advanced Physical Chemistry by J.B. Yadav, Goel Publication

26
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
Analytical Chemistry (Chemistry Elective 1)
Semester V Paper 11 X (P11) Credits 4
Course Outcome:
CO 1. Understand the basic of this course and think & develop new ideas
and concepts in analytical chemistry.
CO 2 . Know about electroanayltical, thermoanalytical, radiochemical,
chromatographic and spectral techniques.
CO 3. To study concepts and theories behind basic methods and techniques
used in analytical chemistry. This theory can be used to solve many rigorous
problems of universe.
CO 4. To prepare the students for further research in analytical methods of
chemistry.
Unit-I
Electroanalytical Techniques:
a. Conductometric: Discussion of the nature of the curves of acid-
base (including mixtures of acids), precipitation and complexometric
titrations
b. Potentiometric: Different types of electrodes, discussion of the
nature of the curves for oxidation-reduction and acid-base titrations,
comparision with the conductometric method
c. Voltametry: Cyclic voltametry
d. Polarography: Dropping mercury electrode and its advantages,
polarographically active species, concept of residual, diffusion and
limiting current of half wave potential, Ilkovic equation and factors
affecting diffusion current
Unit-II
Thermoanalytical Methods:
a. Thermogravimetry: Apparatus, factors affecting TG, Interpretation
of TG curves of CaC2O4.H2O and MgC2O4.2H2O
b. Differential Thermal Analysis and Differential Scanning
Calorimetry: Apparatus, factors affecting DTA and DSC curves
with special reference to heating rate, particle size and packing,
measurement of heat of transition, heat of reaction and heat of
dehydration of salts and metal hydrates.
Unit-III
Radiochemical Methods
a. Isotope method
b. Inverse isotopic dilution
c. Neutron activation technique

27
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
Unit-IV
a. Chromatographic Method:
(i) Gas Chromatography: GLC and GSC
(ii) HPLC
b. Spectral Methods:
(i) Nephelometry
(ii) Turbidimetry
(iii) Flame Photometry

Reference Books:
a) Fundamentals of Analytical Chemistry: D.A. Skoog, D.M. West and F.J.
Holler, 1992, 6e
b) Quantitative Inorganic Analysis, A.I. Vogel, 2012, 7e
c) Instrumental Methods of Chemical Analysis: B.K. Sharma, 2011
d) Instrumental Methods of Chemical Analysis: H. Kaur, 2016, 12 e
e) Analytical Chemistry, Gary D. Christian, 2007, 6e
f) Instrumental Methods of Analysis: H.H. Willard, L.L. Merrit, Jr. J.A.
Dean, 1974

28
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
Chemical Energetics and Radiochemistry (Chemistry Elective 2)
Semester V Paper 11Y (P11) Credits 4
Course Outcome:
Student will
CO 1. Understand the introductory quantum mechanics and concept of
third law of thermodynamics, distribution law and phase rule.
CO 2. Get introduced to the law of photochemistry and photosensitized
reactions energy transfer processes.
CO 3. Study about the dilute solutions and colligative properties.
CO 4. Get familiar with radiopharmaceuticals and radiochemistry.

Unit 1
I.Introductory Quantum Mechanics: Plank's radiation law, photoelectric effect,
Optical activity, polarization (clausius-Mossotti equation), orientation of
dipoles in an electric field, dipole moment, induced dipole moment,
measurement of dipole moment, temperature method and refractivity method,
magnetic properties – paramagnetism, diamagnetism and ferromagnetism
II.Third law of thermodynamics, Nernst heat theorem .Thermodynamic
derivation of Nernst distribution law and its application. Phase rule, Derivation
of Gibbs phase rule and its application.
Unit II
III. Photochemistry
1. Interaction of radiation with matter, difference between thermal and
photochemical processes.
2. Laws of photochemistry: Grothus-Drapper law, Stark-Einstein law,
Jablonski diagram depicting various processes occurring in the excited
state, qualitative description of fluorescence, phosphorescence, non-
radiative processes (internal conversion, intersystem crossing),
quantum yield, photosensitized reactions- energy transfer processes
(simple examples).
Unit III
IV. Solutions, Dilute Solutions and Colligative Properties:
Ideal and non-ideal solutions, methods of expressing concentration of
solutions, activity and activity coefficient, Dilute solution, Raoult's law, relative
lowering of vapour pressure, molecular weight determination, Osmosis, theory
of osmotic pressure and its measurement, determination of molecular weight
from osmotic pressure, Elevation of boiling point and depression of freezing
point and its thermodynamic relation. Experimental methods of determining
various colligative properties. Abnormal molar mass, degree of dissociation
and association of solutes.

29
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
Unit IV
Radiochemistry
Natural and induced radioactivity; radioactive decay----α-decay, β-decay, γ-
decay; neutron emission, positron emission, electron capture; unit of
radioactivity (Curie); half life period; Geiger-Nuttal rule, radioactive
displacement law, radioactive series. Measurement of radioactivity: ionization
chamber, Geiger counters, scintillation counters. Applications: energy tapping,
dating of objects, neutron activation analysis, isotopic labelling studies,
nuclear medicine-99mTc radiopharmaceuticals

Reference Books:
a) Physical Chemistry G.M. Barrow. International Student Edition IMC
McGraw Hill.
b) Graduate Physical Chemistry, Volume III L.R. Sharma and M.S.
Pathania, 2017.
c) Principles of Physical Chemistry, Volume III, B.R. Puri, L.P. Sharma
and M.S. Pathania, Vishal Publications, Jalanadhar.
d) Quantum Chemistry by R.K. Prasad.
e) Elements of Physical Chemistry, P.W. Atkins, Oxford
f) Physical Chemistry, R.A. Alberty: Wiley Eastern Ltd.
g) Physical Chemistry through Problems, S.K. Dogra and S. Dogra Wiley
Eastern Ltd.

30
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)

Chemistry Internship
Semester V IS Credits 4

Course Outcome
• CO1 In a specialisation domain of their choice, students will be able to
choose an appropriate topic for study and will be able to clearly
formulate and state a research problem
• CO2 For a selected research topic, students will be able to compile the
relevant literature and frame hypotheses for research as applicable
• CO3 For a selected research topic, students will be able to plan a
research design including the sampling, observational, statistical and
operational designs if any
• CO4 For a selected research topic, students will be able to compile
relevant data, interpret & analyze it and test the hypotheses wherever
applicable
• CO5 Based on the analysis and interpretation of the data collected,
students will be able to arrive at logical conclusions and propose
suitable recommendations on the research problem
• CO6 Students will be able to create a logically coherent project report
and will be able to defend their work in front of a panel of examiners

Topic Selection
• Students have to submit a theoretical study in any one of the
suggested topics given below in consultation with their teachers.
• These topics are only suggestive. Teachers may allot some other
topics. In case students are allotted topics which are not in this list the
information has to be communicated to the Head, Department of
Chemistry, University of Lucknow
• A comprehensive report has to be prepared and submitted in the
institution where the student is enrolled. Evaluation will be done on the
basis of presentation and viva will be conducted internally.

Suggested Topics
• Organomagnesium compounds and associated chemical reactions.
• Organolithium compounds formation and reactions.
• Analgesics and antipyretic agents
• Anti- inflammatory agents
• Antibacterial and antifungal agents
• Antiviral agents
• Structure and stereochemistry of amino acids
• Classical peptide synthesis, solid phase peptide synthesis

31
 DEPARTMENT OF CHEMISTRY
UNIVERSITY OF LUCKNOW, LUCKNOW
Four Year Undergraduate Course Structure
Subject: Chemistry
(For students admitted till session 2022-23)
• Synthetic and Natural Polymers
• Synthetic Dyes
• Colorimetric methods
• Adsorption and Partition Chromatography
• Thermogravimetric analysis
• Fluorescence and Phosphorescence
• Laws of Photochemistry and their applications
• 99m
Tc as an imaging agent in nuclear medicine
• Fate of excited electronic states
• Neutron activation analysis
• DTA and DSC
• Polarography and its applications
• Voltametric and Potentiometric methods
• Pyrrole and Pyridine: Synthesis and Reactions
• Quinoline and isoquinoline: Synthesis and Reactions
• Configuration and conformation of monosaccharides
• An introduction to disaccharides with special reference to maltose,
sucrose, lactose
• Phase rule
• Magnetic properties – Paramagnetism, diamagnetism and
ferromagnetism
• Experimental methods of determining various colligative properties
• Measurement of radioactivity using ionization chamber, Geiger
counters, scintillation counters.
• Thermodynamic derivation of Nernst distribution law and its application
• Refractometry and Polarimetry
• Syndiotactic, isotactic and atactic polymers
• The double helical structure of DNA
• Classical and solid phase peptide synthesis
• Structure and nomenclature of peptides and proteins
• Experimental methods of studying Chemical Kinetics
• Methods used to determination of solubility and solubility product of
sparingly soluble salts
• Role of Buffers in Chemistry
• Colloids and their applications

32
 Internship Report

On

NAME OF THE TOPIC

NAME OF THE STUDENT

Roll No:
B.Sc. Chemistry Semester-V

Submitted to

NAME OF THE FACULTY MEMBER

Department of Chemistry

NAME OF THE COLLEGE

ADDRESS OF THE COLLEGE

 ACKNOWLEDGEMENTS

Font: Arial Font Size: 12 Normal

Name of the Candidate

Contents to be covered

1. Introduction: 5-10 Pages

Title: Font: Arial; Font Size: 13; Bold
Subtitle: Font: Arial; Font Size: 12; Italics
Content: Font: Arial; Font Size: 12; Normal
2. Discussion: 5-10 Pages
Title: Font: Arial; Font Size: 13; Bold
Subtitle: Font: Arial; Font Size: 12; Italics
Content: Font: Arial; Font Size: 12; Normal
3. References
Font: Arial; Font size: 11

Reference Style

Reference to a journal publication:

[1] J. van der Geer, J.A.J. Hanraads, R.A. Lupton, The art of writing a scientific article,
J. Sci. Commun. 163 (2010) 51–59.
Reference to a journal publication with an article number:
[2] J. van der Geer, J.A.J. Hanraads, R.A. Lupton, 2018. The art of writing a scientific
article. Heliyon. 19, e00205.
Reference to a book:
[3] W. Strunk Jr., E.B. White, The Elements of Style, fourth ed., Longman, New York,
2000.
Reference to a chapter in an edited book:
[4] G.R. Mettam, L.B. Adams, How to prepare an electronic version of your article, in:
B.S. Jones, R.Z. Smith (Eds.), Introduction to the Electronic Age, E-Publishing Inc.,
New York, 2009, pp. 281–304.
Reference to a website:
[5] Cancer Research UK, Cancer statistics reports for the UK.
http://www.cancerresearchuk.org/ aboutcancer/statistics/cancerstatsreport/, 2003
(accessed 13 March 2003).