केन्द्रीय विद्यालय संगठन, कोलकाता संभाग

KENDRIYA VIDYALAYA SANGATHAN, KOLKATA REGION

प्री-बोर्ड परीक्षा / PRE-BOARD EXAMINATION – 2024-25

कक्षा / CLASS – बारहिीं/ 12 अविकतम अंक/MAX. MARKS – 70

विषय /SUB. - जीि विज्ञान/ Biology (044) समय/TIME – 03 घंटे/Hours

General Instructions: -
(i) All questions are compulsory.
(ii) The question paper has five sections and 33 questions.
(iii) Section–A has 16 questions of 1 mark each; Section–B has 5 questions of 2 marks each;
Section– C has 7 questions of 3 marks each; Section– D has 2 case-based questions of 4
marks each; and Section–E has 3 questions of 5 marks each.
(iv) There is no overall choice. However, internal choices have been provided in some
questions. A student must attempt only one of the alternatives in such questions.
(v) Wherever necessary, neat, and properly labelled diagrams should be drawn.

Section – A
Q. No. 1 to 12 are multiple choice questions. Only one of the choices is correct. Select and
write the correct choice as well as the answer to these questions.

Q. Question Marks
No.
1 Which of these plants produces both chasmogamous & cleistogamous 1
(a) Viola
(b) Oxalis
(c) Commenlina
(d) all the above
2 Foetal ejection reflex inhuman female is induced by 1
(a)Release of oxytocin pituitary
(b)Fully developed foetus and placenta
(c)Differentiation of mammary gland
(d)Pressure exerted by amniotic fluid

3 If a cross between two individuals produces offspring with 50% dominant 1

character(A) and 50% recessive character (a) the genotype of parents is
(a) Ww x Ww
(b) Ww x ww
(c) ww x ww.
 (d) WW x Ww

4 Polygenic inheritance occurs in 1

(a) Human eye colour and sickle cell anaemia
(b) Hair pigment in Mouse and tongue rolling in humans
(c) Human height and skin colour
(d) ABO blood group in human and flower colour in Mirabilis jalapa
5 Compare the following characteristics of two operons: 1
Operon Type Response to Structural Genes
Metabolite Activity
Lac Operon Inducible Activated in Inactive without
presence of lactose
lactose
Trp Operon Repressible Inhibited in Active without
presence of tryptophan
tryptophan

Which of the following statements correctly describes the difference between

the lac operon and the trp operon?

(a)Both lac and trp operons are always active, regardless of metabolite presence.
(b)The lac operon is activated by lactose, while the trp operon is activated by
tryptophan.
(c)The lac operon is inducible and requires lactose to activate, while the trp
operon is repressible and requires tryptophan to inhibit.
(d)Both lac and trp operons are inducible operons, activated by the presence of
their respective substrates.

6 A cell is exposed to a chemical inhibitor that specifically blocks the activity of 1

RNA polymerase II in eukaryotes.
What will be the immediate effect of this inhibition on the cell?

(a)Only the transcription of rRNA will be affected.

(b)Transcription of mRNA will stop, affecting protein synthesis.
(c)Transcription of all types of RNA will stop, including rRNA and tRNA.
(d)Transcription will continue unaffected, as the inhibitor targets a different RNA
polymerase.
7 In a couple where both parents are carriers of the autosomal recessive disorder 1
thalassemia, they are considering starting a family. Using your understanding of
inheritance patterns, what is the probability that their child will be affected by
thalassemia, and how would you explain the genetic basis behind this outcome?

(a)0% chance, as carriers cannot pass the disease to their children.

(b)25% chance, because both parents have a 50% chance of passing on the
defective gene, leading to one quarter of their offspring being affected.
(c)50% chance, since the child will inherit one mutated gene from each parent.
 (d)75% chance, as both parents are carriers, increasing the likelihood of the child
inheriting the disorder.
8 A mutation introduces a premature stop codon (UAA) in the middle of an mRNA 1
sequence.

What will be the most likely outcome of this mutation?

(a)Translation will terminate prematurely, producing a truncated, likely non-

functional protein.
(b)The protein will be synthesized normally but with a different amino acid
sequence.
(c)The ribosome will ignore the stop codon and continue translation to the end
of the mRNA.
(d)The stop codon will not affect translation, as it is only functional at the end of
the sequence.

For visually impaired students

A mutation introduces a premature stop codon (UAA) in the middle of an mRNA
sequence.
What will be the most likely outcome of this mutation?

(a)Translation will terminate prematurely, producing a truncated, likely non-

functional protein.
(b)The protein will be synthesized normally but with a different amino acid
sequence.
(c)The ribosome will ignore the stop codon and continue translation to the end
of the mRNA.
(d)The stop codon will not affect translation, as it is only functional at the end of
the sequence.

9 The idea of natural selection depends on all the following except: 1

(a) Variation in traits within a population.
(b) Overproduction of offspring.
(c) Survival and reproduction of individuals with advantageous traits.
(d) Intentional choices made by individuals to evolve.
10 Refer to the diagram of the fermenter shown below. Which labelled part 1
controls the pH and temperature during the fermentation process?

(a) A (Agitator)
(b) B (Sterile air supply)
(c) C (Cooling jacket)
(d) D (Sampling point)

For visually impaired students:

Which part of the bioreactor controls the pH and temperature during the
fermentation process?
(a) A (Agitator)
(b) B (Sterile air supply)
(c) C (Cooling jacket)
d) D (Sampling point)
11 Raj is studying certain organisms and found its base composition to be A=22%, 1
T=28%, G=20%and C=30%. What will be his conclusion regarding its genetic
material?
(a)single stranded RNA
(b)single stranded DNA
(c)double stranded RNA
(d)double stranded DNA

12 Match the following list of bioactive substances and their roles: 1

Bioactive Substance Role

A.Statin i.Removal of oil stains
 B. Cyclosporin A ii. Removal of clots from blood vessels

C. Streptokinase iii. Lowering of blood cholesterol

D. Lipase iv. Immuno-suppressive agent

Choose the correct match:
a. A-ii, B-iii, C-i, D-iv
b. A-iv, B-ii, C-i, D-iii
c. A-iv, B-i, C-ii, D-iii
d. A-iii, B-iv, C-ii, D-i

Question No. 13 to 16 consist of two statements – Assertion (A) and Reason

(R). Answer these questions selecting the appropriate option given below:
A. Both A and R are true and R is the correct explanation of A.
B. Both A and R are true and R is not the correct explanation of A.
C. A is true but R is false.
D. Both Assertion and Reason are false.

13 Assertion: The tapetum is responsible for nourishing developing pollen grains 1

during microsporogenesis.
Reason: Tapetal cells are multinucleate and provide essential nutrients and
enzymes required for pollen wall formation.
14 Assertion: Agrobacterium tumefaciens is popular in genetic engineering 1
because this bacterium is associated with roots of all cereals and pulse
crops.
Reason: A gene incorporated in the bacterial chromosomal genome
gets automatically transferred to the crop with which the bacterium is
associated.

15 1
Assertion: Leguminous plants are nitrogen fixers.

Reason: Leguminous plants have Rhizobium in their root nodules.

16 1
Assertion (A): Gel electrophoresis is used to separate DNA fragments based
on their size.
Reason (R): DNA fragments move through the gel matrix towards the positive
electrode because DNA has a positive charge.
 Section - B
17 Identify the labelled parts A, B, C and D. 2

For visually impaired students:

Name the four important parts of a seminiferous tubules.

OR
(a)Name the stage of the human embryo that gets implanted in the uterus.
(b)Draw its labelled diagram.

18 An HIV-positive individual has been living with the virus for several years and 2
is currently receiving antiretroviral therapy (ART). The healthcare provider
discusses various factors that influence the progression of HIV infection,
including the role of the virus in immune system dysfunction and the
importance of viral load monitoring.
Describe how HIV enters and replicates within host cells.
19 During protein synthesis, the mRNA codon AUG plays a crucial role. 2
What amino acid does this tRNA carry, and why is this amino acid critical for
protein synthesis?
OR
Explain the dual function of AUG codon. Give the sequence of bases it is
transcribed from and its anticodon.

20 In genetic engineering and plant biotechnology, the biolistic gun (or gene gun) is 2
an essential tool used for delivering DNA into plant cells.
How this method compares to other techniques used for gene transfer, such as
Agrobacterium-mediated transformation?
21 In ecosystem ecology, pyramids of biomass illustrate the distribution of biomass 2
among different trophic levels. There are different types of pyramids of biomass,
each representing unique ecological relationships.
What factors might lead to variations in the shape of the pyramids?
OR
In the study of ecosystems, understanding productivity is crucial for
evaluating energy flow and ecosystem health.
Analyze how environmental factors influence both NPP and GPP.
Section - C
22 Observe the following cross and answer the following: 3
(a)Identify the given phenomenon.

(b) What would be the phenotypic and genotypic ratio of individuals of F2

generation?
(c) What results in the production of pink flowers in the F1 generation?

For visually impaired students

(a) Consider a scenario where two plants are being studied for their flower
colors. One plant has red flowers (RR), and another has white flowers (rr). When
these two plants are crossed, the offspring produce pink flowers (Rr),
demonstrating a unique pattern of inheritance. What is this pattern of
inheritance called?
(b) What would be the phenotypic and genotypic ratio of individuals of F2
generation?
(c) What results in the production of pink flowers in the F1 generation?

OR

Observe the given pedigree for the trait colour blindness and answer the
following questions:
 a) Identify whether the given pedigree is Autosomal /X linked and Dominant
/Recessive.
b) What could be the genotype of parents in the First generation?
c) Depict the genotype and phenotype of females in III generation.

For visually impaired students.

(i)Explain why hemophilia is more common in males than females.
(ii)Describe how it is passed down from parents to their children.
23 Set up: An area with different species of plants. A colour tracer is added to the 3
pollen of species A.
Observation: The pollen from species A reaches the flowers of species A as well
as species B. However, pollination occurs only with the flower of the species A.
(a) Name and explain the phenomenon underlying this observation.
(b) How can a farmer prevent any more pollen grains from landing on the stigma
of flowers of the same species after she has artificially pollinated the flowers?

24 Observe the given graph that shows hormonal changes during the menstrual 3
cycle.
a) Identify the phases of the menstrual cycle
b) Explain the role of LH and FSH peaks.
 For visually impaired students:
a) Describe the phases of the menstrual cycle
b) Explain the role of LH and FSH peaks.

25 In a quiet neighbourhood, a woman had been murdered at her home when her 3
roommates were supposedly away. Her roommates were two twin brothers (S1
and S2) and another woman (S3). The investigating officer found the skin of the
murderer under her fingernails. The officer sent the DNA from the skin sample
along with DNA from the roommates for DNA profiling. Given below is an image
of the bands obtained.

(a) Who is likely to be the murderer? Give a reason to support your answer.
(b) S1 and S2 are twin brothers. What can you conclude about them from the
image?

26 The primary effluent in the treatment of sewage is sent to tanks for secondary 3
treatment in the presence of aerobic bacteria.
 (a) Your team is considering using anaerobic bacteria instead of aerobic
bacteria for secondary treatment. Analyse how this change would impact the
Biochemical Oxygen Demand (BOD) of the effluent. What implications might this
have for downstream water quality and regulatory compliance?
(b) Name one condition that should be maintained in a sludge digester where
biogas is produced.
(c) The slurry formed after biogas production is recommended as manure for
plants. Which nutrients will the slurry be rich in and why?

27 Explain the significance of using Taq polymerase in the PCR process. What 3
makes it suitable for this technique?
OR
Given below the diagram of maturation of a proinsulin
into insulin.

(i) How are the two short peptides chains of insulin

linked together?
(ii) State the role of C peptide in human insulin?
(iii) Mention the chemical change that pro insulin
undergo to be able to act as mature insulin.

For visually impaired students

(i)Explain the process of maturation of proinsulin into insulin.
(ii)Describe the structural changes that occur during this process.
28 In nature, the living organisms such as animals plants and microbes 3
cannot live in isolation and therefore, interact in various way to form a
biological community.
i)What will happen if predators are absent?
ii)How does Monarch butterfly is highly distasteful to predators.
iii)Majority of parasties harm the host. Give any two ways.

Section - D
29 Natural selection can influence distribution of phenotype in three 4
different ways as shown below in the figure. Based on this figure answer
the questions that follow:
 (i) Based on the given graphs, what conclusion can you draw about case X
and Y?
(ii)What is the significance of higher and narrower peak in case X?
(iii)What does graph in case Y indicates? Give suitable example.
(iv)What would happen if population is converted into case Z?

For visually impaired students:

Discuss the different types of natural selection by analyzing how specific
trait variants are favored or selected within a population.

30 After a surgery drug ‘X’ was injected to the patient to counteract the effect 4
of pain receptors in the body and to induce sleep in patient. The structure of
the drug ‘X’ is provided:
(i)Identify the drug from the chemical structure that was injected to the
patient.
(ii)Give the scientific name of the plant that can be used to obtain drug
X.
(iii)Write the effects of compound obtained by drug X on the human body.
(iv)To which group X belongs to? Mention the location of its receptors
in human body.

For visually impaired students

After surgery, a drug referred to as 'X' was administered to a patient to
counteract pain receptors and induce sleep.
(i)Describe the mechanism by which drug 'X' might alleviate pain in the patient
after surgery. Discuss how it interacts with the nervous system to block pain
signals.
(ii)Explain the potential benefits of using a drug that induces sleep post-surgery.
How might sleep contribute to the healing process for the patient?
(iii)Discuss any possible side effects or considerations that healthcare providers
should monitor when administering a drug that affects pain perception and
sleep.
OR
Cancer is one of the most dreaded diseases that is a major cause of
death across the globe. It is a non-communicable form of disease that
cannot be transmitted from one person to another or can be said that
these are not transmitted by pathogens. In cancerous cell, the property
of contact inhibition is mainly lost. As a result of which they show continuous
growth and produces a tumour.
(i)How many types of tumour are there. Which is more dangerous form ?
(ii)Draw a diagram showing a formation of a tumour.
(iii)List any two treatments of cancer.
 Section - E

31 A young child is diagnosed with Adenosine Deaminase (ADA) deficiency, a 5

genetic disorder that severely weakens the immune system. This condition is
caused by a mutation in the gene responsible for producing the ADA enzyme,
which helps in the breakdown of toxic substances in the body. Without
treatment, the child's immune system cannot function properly, making them
susceptible to infections. The family is exploring treatment options that involve
gene therapy.
(i)Explain how ADA deficiency affects the immune system and the body’s ability
to fight infections.
(ii)Describe the principle of gene therapy and how it can be used to treat ADA
deficiency. What steps are involved in the gene therapy process for this
condition?
(iii)Analyse the long-term impact of gene therapy for ADA deficiency and how
this biotechnology application represents a breakthrough in treating genetic
disorders. Discuss any ethical concerns associated with this treatment.
(1+2+2=5)
OR
(i) Bacillus thuringiensis (Bt) has played a significant role in agricultural
biotechnology. Explain why it is considered suitable for the development of
genetically modified (GM) plants. Discuss the benefits that Bt provides to these
crops.
(ii) Describe the process through which Bacillus thuringiensis has been used to
develop genetically modified (GM) crops.
32 (a) Biodiversity plays a crucial role in maintaining the stability and functionality 5
of ecosystems. Understanding its importance and the factors contributing to its
depletion is essential for effective conservation strategies.
Based on your understanding of biodiversity, propose three actionable strategies
that could be implemented to conserve biodiversity in your local ecosystem.
Justify why these strategies would be effective.
(b) Describe two main reasons for depletion of Biodiversity.
OR
(a)Describe the in situ and ex situ methods used for biodiversity conservation in
India.
(b)Provide examples of each approach to highlight how they contribute to
preserving the country’s biodiversity.

33 (a)Why is Saheli considered an effective contraceptive for women to 5

space children?
(b)Briefly give an account of any two intra uterine contraceptive
measures. State two advantages? How do they function?
OR
(a)Identify A, B, C and D with reference to gametogenesis in humans, in
the flow chart given below.

(b) In which part of the human female reproductive system do the

following events take place?
I- Release of 1st polar body.

II-Release of 2nd polar body.

III-Fertilisation,

For visually impaired students

Describe the stages of spermatogenesis, focusing on the transformation of
spermatogonia into mature sperm cells.

***************