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    S2 Review | Unit 4 Central Dogma

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    S2 Review | Unit 4 Central Dogma

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    ednaramarao
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    S2 Review | Unit 4 Central Dogma

    Uploaded by

    ednaramarao

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    © All Rights Reserved
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    Central Dogma

    Unit 4 Review

    Overarching Concepts

    1. DNA holds the code of life. Identify what, exactly, it encodes.

    2. Identify the segment of DNA that holds a particular code.

    3. Predict might be the end result of changes to the DNA code.

    4. Describe the term gene expression.

    5. Explain why the expression of genes must be controlled (turned on/off).

    4.1 | Protein Synthesis

    1. Explain how is the DNA code read during Transcription,

    2. Explain how a protein is constructed during Translation.

    3. Describe or draw & label the structural components of an amino acid.

    4. Explain how the DNA code eventually affects the 3-Dimensional shape of a protein.

    5. Describe two causes of protein denaturation.


    4.2 | Mutations
    1. Describe the difference between a point mutation and a frameshift mutation.

    2. In the table below, model transcription and translation.

    1 2 3 4 5 6 7 8

    DNA TAC GCT GCG CGA GCC AGC TTA ATC

    mRNA

    Amino Acid

    3. Imagine that the 1st base of the 3rd DNA triplet experiences a substitution mutation: the 1st G -> C. List the
    resulting amino acid sequence and identify the type of mutation (silent, missense, nonsense) that occurred.

    4. Imagine that the 7th DNA triplet experiences a deletion of its first T nucleotide. Explain how this mutation
    would effect the resulting protein’s structure AND function.

    4.3 | Control of Gene Expression


    1. Explain why gene expression is regulated differently in eukaryotes and prokaryotes.

    2. Explain how eukaryotic gene regulation & cell differentiation during development (Unit 1!) are related.

    3. Identify all parts of the OPERON, which is the


    main source of regulation of gene expression
    in prokaryotes. —------------------------->

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