W1 L1 Pituitary Gland ICA

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Level 2

Semester 4
Module (endocrine)
Pituitary gland
And
Internal carotid artery
PITUITARY GLAND
(HYPOPHYSIS CEREBRI)
It is referred to as the master of endocrine
glands.
It is a small oval structure 1 cm in diameter.
It doubles its size during pregnancy.

• Endocrine gland

• lies in the hypophyseal (pituitary) fossa

• Consists of 2 lobes (large anterior lobe and


small posterior lobe).
POSITION
It lies in the middle cranial
fossa It is well protected in sella turcica
(hypophyseal fossa) of body of sphenoid

Sella turcica
Optic chiasma
Mamillary body

Body of sphenoid

 it lies between Optic chiasma (anteriorly) & Mamillary


bodies (posteriorly).
IMPORTANT RELATIONS

SUPERIOR: Diaphragma sellae


INFERIOR: Sphenoidal air sinuses
LATERAL: Cavernous sinuses
Diaphragma sellae : A fold of dura mater covers the pituitary
gland & has an opening for passage of infundibulum (pituitary
stalk) connecting the gland to hypothalamus.
Summary of pituitary relations:
1. Superior : Diaphragma sellae , Optic chiasma and
infundibulum connecting the pituitary gland to
hypothalamus.

2. Below: Body of sphenoid & Sphenoidal air sinuses.

3. Posterior : Dorsum sellae and brain stem.

4.Anterior : Tuberculum sellae is the anterior wall of the


pituitary fossa.

5.On each side: Cavernous sinus containing internal


carotid artery and abducent nerve.
SUBDIVISIONS OF PITUITARY GLAND

Hypothalamo-hypophyseal
tract

The gland is subdivided into:


Anterior Lobe (Adenohypophysis): it is the True gland, Secretes
hormones
Posterior Lobe (Neurohypophysis): connected to hypothalamus
through hypothalamo-hypophyseal tract, Stores hormones secreted
by hypothalamic nuclei
BLOOD SUPPLY OF PITUITARY GLAND

ARTERIES: Superior & Inferior hypophyseal arteries (branches


from Internal Carotid artery)
VEINS: Hypophyseal veins drain into Cavernous Sinuses.
DISTRIBUTION OF ARTERIES

a hypothalamo-
hypophseal
portal vessel

Superior hypophyseal: supplies infundibulum & forms a capillary network from


which vessels pass downward & form sinusoids into the anterior lobe of pituitary
gland (hypophyseal portal system).
Inferior hypophyseal: supplies posterior lobe of pituitary gland.
ANTERIOR LOBE
Hormone-releasing & inhibiting
factors produced by hypothalamus
use Hypophyseal Portal System of
vessels to reach the Anterior lobe of
pituitary gland
POSTERIOR LOBE
The Neurohypophysis receives a nerve
supply from some of the hypothalamic
nuclei (supraoptic & paraventricular)
The axons of these nuclei convey their
neurosecretion to the Posterior lobe of
pituitary gland through Hypothalamo-
Hypophyseal tract from where it passes
into the blood stream.
Internal carotid artery
INTERNAL CAROTID ARTERY
Origin & termination:
• Arises from CCA opposite the upper
border of thyroid cartilage
• and ends at the base of brain, lateral to
the optic chisma by dividing into
anterior and middle cerebral arteries.
• At its beginning it shows a localized
dilatation called the carotid sinus.
Internal carotid artery

 Course:
• 1) cervical part: Ascends in the neck embedded in the
carotid sheath with the internal jugular vein and
vagus nerve.
• At first it lies superficially; it then passes deep to the
parotid salivary gland

• 2) intrapetrous part: Leaves the neck by passing into


the cranial cavity through the carotid canal in the
petrous part of the temporal bone. Passing upwards,
forwards and medially
• Finally reaches the cranial cavity through the foramen
lacerum
Internal carotid artery
3-Intercavernous part: at the upper end of
f.lacerum ,
I.C.A pierce the post wall of the cavernous sinus
,then it run inside the cavity of the sinus
,then it curves upwards to pierce the roof of the
sinus

4-Intercranial part: after emerging from the roof


of the cavernous sinus ,I.C.A bends upward above
the sinus ,below the optic nerve .till it reaches
the ant.perforated substance of the brain
where it ends by dividing into its two terminal
branches.
Relations:
• (a)cervical part:
• Anterolaterally:
• Below the digastric : skin, fascia, anterior border of the
sternomastoid, and hypoglossal nerve
• Above the digastric: stylohyoid and stylopharyngeus muscles,
glossopharyngeal nerve, pharyngeal branch of vagus, parotid
gland, and external carotid artery
• Posteriorly: sympathetic trunk , longus capitis muscle, and
transverse processes of upper three cervical vertebrae
• Medially: pharyngeal wall and superior laryngeal nerve
• Laterally: internal jugular vein and vagus nerve
Relations:
• (b)Intra petrous part:
 The ICA lies infront of the middle& internal ear
cavities.
 It is surrounded by 2 plexuses:
• (a) venous plexus.
• (b) plexus of symp.fibers derived
from
• internal carotid nerve.
Relations:

• (C) intracavernous part:

 Medially: body of sphenoid(contaning


sph.air.sinuses)
• &Pituitary gland.
 Laterally: Abducent nerve.

occlumotor,trochlear,opthalamic&maxillary
nn.
• (embded in the lat.wall)
 Antrosuperiorly: optic n.
Relations:

• (d) Intra cranial part:


• After emerging from the cavernous sinus ,
passes upward again medial to the anterior
clinoid process of the sphenoid bone.
• Inclines backward, lateral to the optic
chiasma, and terminates by dividing into the
anterior and the middle cerebral arteries.
Branches of ICA:
• 1) cervical part:
• It gives off no branches in the neck
(boy)
• 2) intrapetrous part:
• 1-2 caroticotympanic arteries to the
middle ear cavity
• Small branch to the pterygoid canal
• 3) cavernous part:
• Superior and inferior hypophyseal
arteries
• Meningeal branches
Branches of ICA:

• 4) intracranial part:

• Ophthalmic artery.
• Posterior communicating artery.
• Anterior choroidal artery.
• Anterior cerebral artery.
• Middle cerebral artery.

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