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    Hepatitis e Virus 1

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    nadianajatnajat

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    © All Rights Reserved
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    Hepatitis e Virus 1

    Uploaded by

    nadianajatnajat
    2 views7 pages

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    2 views7 pages

    Hepatitis e Virus 1

    Uploaded by

    nadianajatnajat

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 7

    HEPATITIS E VIRUS

    BY- DR ISRAT JAHAN DINA


    HEPATITIS E VIRUS
    • HEV is a major cause of hepatitis
    transmitted by the fecal-oral
    route.
    • It is thought to be more common
    than HAV in many developing
    countries.
    • .
    • Properties:HEV is a
    nonenveloped, single-stranded
    RNA virus classified as a
    member of the hepevirus
    family.
    • Clinical features: Clinically, the
    disease resembles hepatitis A,
    with the exception of a high
    mortality rate in pregnant
    women. Most cases resolve
    without sequelae.
    • Chronic infection resulting in chronic
    hepatitis and cirrhosis, but not HCC,
    occurs in immunocompromised
    individuals such as HIV-infected
    patients, those who are receiving
    cancer chemotherapy, and patients
    who are receiving immuno-
    suppressive drugs to prevent rejection
    of solid organ transplants.
    • Diagnosis:The diagnosis is
    typically made by detecting
    IgM antibody to HEV. A PCR
    assay that detects HEV RNA in
    patient specimens is available.
    • Prevention and Treatment :
    There is no antiviral drug
    available for acute infection in
    immunocompetent patients. In
    immunocompromised patients,
    ribavirin cleared HEV viremia in
    solid organ transplant
    recipients. There is no vaccine

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